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Doctor insights on: C1q Complement Component

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I have anemia, vitamin d deficient, positive ANA test, high sed rate, body aches, complement component c3c is 220, c4c is 51, c-reactive is .97explain?

I have anemia, vitamin d deficient, positive ANA test, high sed rate, body aches, complement component c3c is 220, c4c is 51, c-reactive is .97explain?

More than one issue: You did not state your age or gender and it is difficult to tie all the findings together without a physical examination. Vitamin d is the easiest to deal with, about 1/3 of the population has low vit d levels, and you can correct that with an over the counter supplement. Rest of the finding suggest and autoimmune process, but you need to consult a physician for a thorough evaluation. ...Read more

Complement (Definition)

The complement system is an important effector mechanism of both humoral and innate immunity. Its functions are to promote phagocytosis of microbes, to stimulate inflammation, and to induce lysis of these organisms. The system is highly complex and comprised of over 50 effector and regulatory molecules. It is activated via one of three pathways: antibody, lectin, or by ...Read more


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I have anemia, vitamin d deficient, positive ANA test, high sed rate, body aches, complement component c3c is 220, c4c is 51, c-reactive is .97explain?

More than one issue: You did not state your age or gender and it is difficult to tie all the findings together without a physical examination. Vitamin d is the easiest to deal with, about 1/3 of the population has low vit d levels, and you can correct that with an over the counter supplement. Rest of the finding suggest and autoimmune process, but you need to consult a physician for a thorough evaluation. ...Read more

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Can you tell me about immunobiology - complement cascade?

Can you tell me about immunobiology - complement cascade?

Textbook: This is a subject which should be studied with a textbook. Briefly complement is a system whereby the body kills off offenders. However there are check-and-balance system to make sure that it does not go too far leading to unwanted tissue damages. ...Read more

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What does high hemolytic complement mean?

What does high hemolytic complement mean?

Likely response to: Inflammation. Complement is one of the acute phase reactants that increase in response to inflammation in the body. All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. ...Read more

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What would having low complement levels indicate?

What would having low complement levels indicate?

Low complement: Low levels of complement are seen in persons with complement deficiency who are prone to recurrent infections as well as in certain autoimmune conditions, inherited angioedema conditions, and hives associated with vasculitis (inflammed blood vessels). These can all be serious. Collection of blood to measure complement is tricky and needs to be done right or low level could occur. ...Read more

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What do low complement levels indicate is going on?

What do low complement levels indicate is going on?

Some things: To consider: 1) autoimmunity (particularly sle) 2) immunodeficiency 3) blood dyscrasia or cancer. ...Read more

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What does complement alternative pathway test show?

Mechanism for diseas: If you have a disease compatible with a complemented activated disorder, this test may be performed. It is an attempt to detect a mechanism for your disease condition. ...Read more

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What does high immunoglobulin IG m and complement mean?

What does high immunoglobulin IG m and complement mean?

Depends: The "normal ranges" for all lab tests include 95% of the "normal" population; thus, 2.5% of people are above the upper limit, and 2.5% are below the lower limit. There's nothing to worry about if your values are a little bit above the normal range, but a very elevated IgM could be a sign of a problem. You need to check with the physician who ordered the tests to interpret your results. ...Read more

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I have type 1 obesity. What is the best pill to complement my diet?

I have type 1 obesity. What is the best pill to complement my diet?

Weight loss diet: If you are on a weight loss diet, you may be at risk for vitamin deficiencies, especially if you are avoiding fruits, which you should, if you want to lose efficiently. A good multivitamin may be your best friend in this situation. I have my weight loss patients take multivitamins, calcium, potassium, and fish oil. They are on a very low carb, medically supervised diet and they lose quickly. ...Read more

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Can someone please explain what "complement" is in your immune system?

Can someone please explain what "complement" is in your immune system?

Immune swat team: Antibodies are like folks in line at the post office studying the wanted posters. Later they spot a felon (bacteria), grab 'em by the arm & summon the complement swat team. Complement is a group of proteins circulating in extracellular fluid. The team arrives on the scene, assembles in a specific sequence & then punches holes in the bacteria killing it. Antibodies identify; complement rubs 'em out. ...Read more