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Doctor insights on: C1q Complement Component

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I have anemia, vitamin d deficient, positive ANA test, high sed rate, body aches, complement component c3c is 220, c4c is 51, c-reactive is. 97explain?

I have anemia, vitamin d deficient, positive ANA test, high sed rate, body aches, complement component c3c is 220, c4c is 51, c-reactive is. 97explain?

More than one issue: You did not state your age or gender and it is difficult to tie all the findings together without a physical examination. Vitamin d is the easiest to deal with, about 1/3 of the population has low vit d levels, and you can correct that with an over the counter supplement. Rest of the finding suggest and autoimmune process, but you need to consult a physician for a thorough evaluation. ...Read more

Complement (Definition)

The complement system is an important effector mechanism of both humoral and innate immunity. Its functions are to promote phagocytosis of microbes, to stimulate inflammation, and to induce lysis of these organisms. The system is highly complex and comprised of over 50 effector and regulatory molecules. It is activated via one of three pathways: antibody, lectin, or by ...Read more


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I have anemia, vitamin d deficient, positive ANA test, high sed rate, body aches, complement component c3c is 220, c4c is 51, c-reactive is. 97explain?

More than one issue: You did not state your age or gender and it is difficult to tie all the findings together without a physical examination. Vitamin d is the easiest to deal with, about 1/3 of the population has low vit d levels, and you can correct that with an over the counter supplement. Rest of the finding suggest and autoimmune process, but you need to consult a physician for a thorough evaluation. ...Read more

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Can you tell me about immunobiology - complement cascade?

Can you tell me about immunobiology - complement cascade?

Textbook: This is a subject which should be studied with a textbook. Briefly complement is a system whereby the body kills off offenders. However there are check-and-balance system to make sure that it does not go too far leading to unwanted tissue damages. ...Read more

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What does high hemolytic complement mean?

What does high hemolytic complement mean?

Likely response to: Inflammation. Complement is one of the acute phase reactants that increase in response to inflammation in the body. All lab results need to be interpreted in the clinical context and the doctor who ordered the test is usually in the best position to do that. ...Read more

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What would having low complement levels indicate?

What would having low complement levels indicate?

Low complement: Low levels of complement are seen in persons with complement deficiency who are prone to recurrent infections as well as in certain autoimmune conditions, inherited angioedema conditions, and hives associated with vasculitis (inflammed blood vessels). These can all be serious. Collection of blood to measure complement is tricky and needs to be done right or low level could occur. ...Read more

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What do low complement levels indicate is going on?

What do low complement levels indicate is going on?

Some things: To consider:
1) autoimmunity (particularly sle)
2) immunodeficiency
3) blood dyscrasia or cancer. ...Read more

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What does complement alternative pathway test show?

Mechanism for diseas: If you have a disease compatible with a complemented activated disorder, this test may be performed. It is an attempt to detect a mechanism for your disease condition. ...Read more

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What does high immunoglobulin IG m and complement mean?

What does high immunoglobulin IG m and complement mean?

Depends: The "normal ranges" for all lab tests include 95% of the "normal" population; thus, 2.5% of people are above the upper limit, and 2.5% are below the lower limit. There's nothing to worry about if your values are a little bit above the normal range, but a very elevated IgM could be a sign of a problem. You need to check with the physician who ordered the tests to interpret your results. ...Read more

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I have type 1 obesity. What is the best pill to complement my diet?

I have type 1 obesity. What is the best pill to complement my diet?

Weight loss diet: If you are on a weight loss diet, you may be at risk for vitamin deficiencies, especially if you are avoiding fruits, which you should, if you want to lose efficiently. A good multivitamin may be your best friend in this situation. I have my weight loss patients take multivitamins, calcium, potassium, and fish oil. They are on a very low carb, medically supervised diet and they lose quickly. ...Read more

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Can someone please explain what "complement" is in your immune system?

Can someone please explain what "complement" is in your immune system?

Immune swat team: Antibodies are like folks in line at the post office studying the wanted posters. Later they spot a felon (bacteria), grab 'em by the arm & summon the complement swat team. Complement is a group of proteins circulating in extracellular fluid. The team arrives on the scene, assembles in a specific sequence & then punches holes in the bacteria killing it. Antibodies identify; complement rubs 'em out. ...Read more

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Does the human body even use the complement system at all to fight-off viruses?

Does the human body even use the complement system at all to fight-off viruses?

Yes: If viral antigens or epitopes are expressed on the surface of the infected cell, then yes. They may "fix complement" leading to lysis. ...Read more

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I am complement deficient without an autoimmune disorder. What is making me sick?

I am complement deficient without an autoimmune disorder. What is making me sick?

See rheumatologist: Something is eating up your complement and you may need a very good rheumatologist to find why whether there is an autoimmune process going on since negative ANA and RF do not rule out all autoimmune processes. If no cause can be found by your local MD, consider going to an university center. ...Read more

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Why are some complement fragments called opsonins, anaphylatoxins or chemotactic factors?

Why are some complement fragments called opsonins, anaphylatoxins or chemotactic factors?

Related to function: Opsonins bind microbes, particles and cell fragments flagging them for uptake/engulfment by macrophages or neutrophils. Anaphylatoxins, when released, bind to their receptors on macrophages and mast cells to activate the cells. Subsequently, the activated cells release mediators (eg histamine) involved in anaphylaxis and/or inflammation. Chemotactic factors guide WBCs to site of inflammation ...Read more

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What might a slightly elevated total hemolytic complement mean? (ref. Range 52-128, mine-131). Any need for concern?

No: Reference ranges are established so that 95% of healthy couch potatoes fall into them. If your physician is not concerned, I would not be either. ...Read more

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Does hgb A1c test complement a glycomark test?

Yes: Each test has its own utility and measures different mechanism of abnormal glucose metabolism. I would also add a fasting Insulin level and a GGT level into the panel for optimal understanding of what is really going on with the sugar in your body. ...Read more

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What could high immunoglobulin IG m and complement C4 mean?

What could high immunoglobulin IG m and complement C4 mean?

May be significant: Immunogloblin m (igm) is one of the 5 classes of proteins that have antibodies. C4 is part of the complement cascade, a series of proteins that are important in immunity and inflammation. Elevation of both may occur in various diseases. The significance of the specific values for you depends on what your clinical problem is. Therefore, I can not be more specific as to what it means for you. ...Read more

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What foods complement each other well nutritionally?

What foods complement each other well nutritionally?

Whole foods: If you want the best nutritionally rich diet, stick with whole foods, fruits, vegetables, nuts, seeds, and grain. Avoid animal protein and dairy. ...Read more

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What is the definition or description of: complement?

Complement System: The complement system is an important effector mechanism of both humoral and innate immunity. Its functions are to promote phagocytosis of microbes, to stimulate inflammation, and to induce lysis of these organisms. The system is highly complex and comprised of over 50 effector and regulatory molecules. It is activated via one of three pathways: antibody, lectin, or by natural "tick-over" of C3. ...Read more

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What is complement c3?

What is complement c3?

Complement C3: Complement C3 is a blood test that measures the activity of a certain protein that is part of the complement system. The complement system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation. This test is usually elevated in immune diseases or infections. ...Read more

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What does it mean by complement activation?

Complement: Is a series of immune proteins that are usually cause a "chain reaction" of events that lead to inflammation and when activated by infection, hormonal changes, etc., it will cause this chain reaction to start aka complement activation. ...Read more

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What does the complement receptor type 1 do?

CR1: There is some controversy here, but it seems to mainly act through binding of C1q upon forming complexes with antibody in the bloodstream. CR1 is highly expressed on red blood cells, so these cells carry immune complexes away from the site of attachment to the spleen where the immune complexes are destroyed. An "immune complex" is a cluster of antibodies and there antigen targets (like a virus). ...Read more

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How is complement involved in immune responses?

Complement: The complement system helps antibodies and phagocytic cells clear pathogens. It is part of the immune system called the innate immune system that is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system. Generally synthesized by the liver. Stimulated by one of several triggers....Etc. ...Read more

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I am feeling like a failure, complementing suicide each day?

I am feeling like a failure, complementing suicide each day?

Time 2 get support: You can find a local psychologist here http://locator. Apa. Org/. Often medication can help during a time like this. Your psychologist or physician can recommend a psychiatrist, if you’re interested in exploring medication options. If you feel like you are in crisis, please go to the nearest er or call 911. Suicide hotline 800-273-talk. ...Read more

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Can different types of health practitioners complement each other?

Should be a team: For many patients with multiple or complex medical problems several specialist may be indicated to work with the patient and their primary care physician for optimal diagnosis and treatment. Physicians of different specialties most certainly can and should complement each other as long as they stay within the scope of their expertise. ...Read more

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Complement C4 is. 12 (normal is. 14 -.54) is it worth getting repeated.

Complement C4 is. 12 (normal is. 14 -.54) is it worth getting repeated.

Depends: Complement C4 being low could indicate an issue with activation of the complement system such as after infection. It could also be related to liver disease, genetic deficiency of complement, vasculitis, lupus, or even could possibly just be a low-normal value for you. So I would repeat testing only if you have other medical concerns that are currently being evaluated. ...Read more

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What is complement total (ch50) elevated over 60 mean? Any significance?

Basically no: It's more worrisome if it's low. Lab reference ranges are set so that maybe 5% of healthies fall outside on either end. Don't worry. ...Read more

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What is the average weight to complement a person with the height of 5'9"?

What is the average weight to complement a person with the height of 5'9"?

155 pounds!: Good morning,
at 5'9 you are at the 50th percentile (average) height for us men; the corresponding weight for will be 155 pounds. ...Read more

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What food to eat before/after training or competing to help me complement my exercise and lose weight?

What food to eat before/after training or competing to help me complement my exercise and lose weight?

Chocolate milk after: For average person, what to eat, whether before/after exercise, and at what time of day (AM/PM) is really immaterial. Instead, we should be just focusing on exercising. Period. Unless we're an elite athlete, in which case, our coach will set up strict programs & times for both nutrition & exercise. But if you want to obsess over this, check out menshealth. Com, mensfitness. Com & mensjournal. Com. ...Read more