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Doctor insights on: Burr Cells

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What is burr cell?

What is burr cell?

A burr cell: Is a red blood cell with an irregular cellular membrane. It is associated with a change in the lipid (fat) content of the membrane, often in the setting of liver disease. ...Read more

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What causes burr cells?

What causes burr cells?

Disease and artifact: Burr cells are red cells with abnormal shape and may be due to kidney failure or enzyme deficiency. These may also be artifacts. See this site for more info. http://www.medialabinc.net/spg28876/burr_cells_echinocytes.aspx. ...Read more

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What is 2+ burr cell but Cbc for little girl was normal ?

What is 2+ burr cell but Cbc for little girl was normal ?

Means nothing: Burr cells are an artifact of how the smear was pushed when it was made. It is simply a technical note for the lab folks. If she is otherwise healthy, ignore it. ...Read more

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Is it normal for a 2.5 YO to have results of Anisocytosis: Rare Burr Cells: Slight, Microcytes: Rare, Polychromasia: Rare on a morphology Report?


Is it normal for a 2.5 YO to have results of Anisocytosis: Rare Burr Cells: Slight, Microcytes: Rare, Polychromasia: Rare on a morphology Report?

2.5 YO: No, your comments are not "normal". If your child has the issues you report you must continue to see a specialist. If you are not satisfied with the doctor you take tour child, have one of your friends refer you to a doctor with whom you will be more satisfied. Wish the baby well - please keep me posted; we can all learn something. ...Read more

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3 yr old. Very poor growth. Calprotectin 165, ESR 30, burr cells 1+. Very high IGA. Could this be normal or is something definitely wrong? GI related?

3 yr old. Very poor growth. Calprotectin 165, ESR 30, burr cells 1+. Very high IGA. Could this be normal or is something definitely wrong? GI related?

Not normal: Both calprotectin and ESR are measures of inflammation. Since your child's doctor has already started some testing, I encourage you to continue the evaluation. It sounds like your child has been quite ill, and I hope she improves soon. ...Read more

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3yr old. Calprotectin 165. ESR Sed rate 26, Immunoglobulin A 183. Burr cells 1+. Poor weight gain. Could this be normal? GI related?

3yr old. Calprotectin 165. ESR Sed rate 26, Immunoglobulin A 183. Burr cells 1+. Poor weight gain. Could this be normal? GI related?

Not normal: Elevated CRP and ESR suggest an inflammatory process. With a history of pneumonia and adenoidectomy, it sounds like your child has had sigificant illness. With poor weight gain, both GI and Immune dysfunction should be evaluiated by your child's doctor. ...Read more

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3yr old h/O failure to thrive/poor growth. Ped GI found IgA 183, ESR 26, calprotectin 165, burr cells 1+. Plan is to repeat labs & if unchanged colonoscopy. food allergy??? Maybe see allergist too????

3yr old h/O failure to thrive/poor growth. Ped GI found IgA 183, ESR 26, calprotectin 165, burr cells 1+. Plan is to repeat labs & if unchanged colonoscopy. food allergy??? Maybe see allergist too????

Failure to thrive : I think your GI doctor suggested an upper endoscopy with possible sigmoidoscopy. Eosinophilic gastroenteropathy Is a possible reason which is evaluated by biopsies. If the biopsies are consistent with above then next step is an allergist but make sure you see a pediatric allergist who is familiar with this condition. There are other reasons for failure to thrive as well so follow your GI rec's ...Read more

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Does the oldest child decide on a parents burial and medical decisions?

Does the oldest child decide on a parents burial and medical decisions?

Not necessarily: Hopefully this has been decided by your parents before it is necessary . That is what a will is for. Parents usually choose the child who they feel should be in charge and that may or may not be the oldest. Being firstborn doesn't rest that responsibility on one just by virtue of birth order...Unless you are an only child. ...Read more

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Can my untreated teeth be detrimental to my health? I have over $8000 worth of work to get done. With $0 i'm afraid my health will start deteriorating i'm only 25 years old. Should i start making my burial arrangements? Or are there any dentists that do

Can my untreated teeth be detrimental to my health? I have over $8000 worth of work to get done. With $0 i'm afraid my health will start deteriorating i'm only 25 years old. Should i start making my burial arrangements? 

Or are there any dentists that do

Yes, detrimental: See if there is a dental school near you . The treatment is much less expensive -- what you save in money, you pay in time. It takes longer for treatment. You also might find a clinic at a hospital that has a teaching program for postdoctoral dental training. (gpr or aegd). Good luck -- no burial yet ! ...Read more

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Read this in wikipedia: "when a cell s telomeres shorten to critical lengths, the cell senesces" is that how we age?

Read this in wikipedia: "when a cell s telomeres shorten to critical lengths, the cell senesces" is that how we age?

One theory: This one biomarker of aging. Other theories include oxidative stress, and other environmental stressors, genetics, etc. Nature(genetic longevity) and nurture(environmental, how we treat ourselves, medical care) all contribute to the longevity of the human race. ...Read more

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What is/are the best test(s) for detecting a monoclonal plasma cell disorder? How sensitive are these tests? Which types of mpcds can they detect?

What is/are the best test(s) for detecting a monoclonal plasma cell disorder? How sensitive are these tests? Which types of mpcds can they detect?

SPEP: The best test is a serum protein electrophoresis. It is very sensitive and specific. The disease is rare in anyone under the age of 40. For the vast majority of people the disease does not progress for many years 10-20+ so there is no role for screening. ...Read more

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What are LE cells?

What are LE cells?

LE Cells: A neutrophil or macrophage (type of white blood cell) that has been engulfed the denatured nuclear material of another cell. The denatured material is an absorbed hematoxylin body (also called an LE body). They are a characteristic of lupus erythematosus, but also found in similar connective tissue disorders. LE Test for lupus: positive when 10 or more of these cells are seen under microscope ...Read more

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What are b-cells and its functions?

What are b-cells and its functions?

Antibodies: B cells are immune cells that develop in the Bone marrow and mature in the lymphoid organs. They make antibodies that protect our bodies from foreign invaders such as viruses. Most vaccines work by stimulating our body's B cells to make antibodies so that they can already be present to protect us when we are exposed to an actual viral infection. ...Read more

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What is langerhans cell histiocytotis?

What is langerhans cell histiocytotis?

Abnormal cells: Langerhans cell histiocytosis (lch) involves abnormal cells developing from bone marrow which can migrate to different parts of the body. ...Read more

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What are T cells?

What are T cells?

Type of lymphocyte: When lymphocytes were first recognized as a small population of the white blood cells, Bob Good divided them into T and B cells. The T cells were matured in the Thymus and the B cells in the Bursa of Fabricius found in the chicken. The B cells produce antibody andthe T cells contain cells ie. Th 1, making IL2 and the Th2 IL 10. The TH 1 targets bacteria and viruses. ...Read more

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What do T cells do?

What do T cells do?

Lymphocytes: T cells, different types, master the specific immune system, while B cells mainly produce different types of antibodies, under the the control T cells, to fight invading microorganisms and/or invading antigens, just simply put for a very complex system (the immune system) ...Read more

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Abnormal cell growth

Abnormal cell growth

See below: These are symptoms that could be potentially serious. Yous should discuss these with your physician. He/she will thoroughly evaluate you and let you know what's going on. ...Read more

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Helper t cells do what?

Helper t cells do what?

Manage immunity: Helper T cells are unit commanders that instruct soldiers on the front lines. They help B cells secrete protective antibodies. They help "killer" T cells attack infected cells. They also influence the "flavor" of the immune response to favor more of an allergic-type response versus more of a flu-like response. They are CD4 positive cells that are destroyed in HIV/AIDS leading to immunodeficiency. ...Read more

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