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Doctor insights on: Bupropion Medication

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Please describe the medication: bupropion?

Please describe the medication: bupropion?

Bupropion: Also, called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, & elevate blood pressure. ...Read more

Dr. Alan Ali
792 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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Please describe the medication: wellbutrin (bupropion)?

Please describe the medication: wellbutrin (bupropion)?

Major depression: Wellbutrin (bupropion) is used for the management of major depression and seasonal affective disorder (depression that occurs primarily during the fall and winter). Interestingly, it can also be used to help people stop smoking by reducing cravings and other symptoms of withdrawal. Do not take if you have seizures or an eating disorder or if you have suddenly stopped using alcohol or sedatives. ...Read more

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What can I do for anxiety being caused by wellbutrin? Never had until started the medication last year

What can I do for anxiety being caused by wellbutrin? Never had until started the medication last year

Wellbutrin Anxiety: Desist taking it and talk to your doctor. Remind yourself that it is the likely reason for the anxiety. Breathing is vastly underestimated as a good answer in situations like this. Try to sit and breath deeply and make and keep your breath slow and methodical in and out for five minutes. Stop anytime you need to. Even when I am under a lot of stress I will stop frequently to do so if nec. ...Read more

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I have been taking 150 mg of Wellbutrin (bupropion) XL for one month. What would be the safe way to discontinue this medication?

Wellbutrinmonitoring: Your Emotional Health is Precious!
Please not to go off Wellbutrin (bupropion) abruptly.
If you are not depressed, discuss with Psychiatrist :
• To decrease the dose, • Have Therapy; and • Follow through if any withdrawal symptoms occur. ...Read more

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With all the medications I'm prescribed if you look on my profile, don't you think it's possibly the Wellbutrin that I should ween off?

Discontinuing Meds: Your profile does not include a list of the medications you are prescribed. It poses ethical issues for a doctor who is not the prescribing physician to recommend stopping a med. Wellbutrin is a widely prescribed antidepressant that helps addictive and compulsive behaviors like smoking and overeating with few sexual side effects. About 40% of patients lose weight on it in contrast with SSRI's. ...Read more

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I'm changing my medication from Effexor (venlafaxine) 300mgs to wellbutrin 150mgs. How long before I notice a change in my mood?

I'm changing my medication from Effexor (venlafaxine) 300mgs to wellbutrin 150mgs. How long before I notice a change in my mood?

Many Variables: When switching from one antidepressant to another it is difficult to predict how quickly the new medication will take effect. Generally one expects an antidepressant to begin to work after two weeks with the maximum benefit at six weeks. One should taper slowly off Effexor (venlafaxine) due to discontinuation symptoms. These would include anxiety and flu-like aches and pains. Work closely with your md. ...Read more

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How long does it take a prescription medication like wellbutrin (bupropion) to start working?

How long does it take a prescription medication like wellbutrin (bupropion) to start working?

Can be very fast: Within a few days to weeks, but full effect will take many weeks to manifest. Keep in mind also dose adjustment is usually necessary to get to the right dose. Not being at the right dose can mean no effect at all. Don't give up too soon. ...Read more

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Is there any medication I could take daily to battle anxiety that will not counteract the energy boosting properties of Wellbutrin (bupropion)?

Is there any medication I could take daily to battle anxiety that will not counteract the energy boosting properties of Wellbutrin (bupropion)?

Anxiety: A side effect of many medications for anxiety is sedation, but different people respond differently to different medications. SSRI medications are good for anxiety and can be given with bupropion (Wellbutrin). Sertraline (Zoloft) is approved for anxiety disorders such as panic disorder, and 85% to 98% do not report sedation with it. Exercise, deep breathing exercises, & CBT are VERY helpful also ...Read more

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What medication can be combined with wellbutrin (bupropion) to treat ocd and anxiety?

What medication can be combined with wellbutrin (bupropion) to treat ocd and anxiety?

Quite a few: There are quite a few medicines across multiple classes (SSRI, SNRI, TCA, etc.) that can be added however Rx choice really depends on what symptoms need the "extra help." The goal is to reduce the risk of side effects as much as possible and a lot is dependent on your history/response and prescriber preference. Also, combining psychotherapy + meds helps ensure a better outcome. Hope that helps! ...Read more

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3rd week on bupropion sr 300mg. Depression is getting much worse. Is it typical for the medication to make things get worse before it gets better?

3rd week on bupropion sr 300mg. Depression is getting much worse. Is it typical for the medication to make things get worse before it gets better?

Talk with prescriber: There are many reasons why depression can get worse at the start of therapy. This sort of question really is best addressed one on one with the prescriber. I am concerned that more support is indicated particularly now that you state the depression is even worse than when treatment was started! Effective care is out there but one has to be assertive. Hard when one is depressed. ...Read more

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I'm taking Topamax (topiramate) 200mg and wellbutrin 400mg will they both help me lose weight I'm trying to lose 20 I take for psychotropic medications?

I'm taking Topamax (topiramate) 200mg and wellbutrin 400mg will they both help me lose weight I'm trying to lose 20 I take for psychotropic medications?

Maybe: The manufacturers of Topamax (topiramate) suggest that it can control binge eating, and welbutrin is somewaht activating so they may help. However, the best way to look at these meds is that they are prescribed to treat your psychiatric condition and that at least they are not know for causing weight gain and do not stand in your way. Topamax (topiramate) is a serious medication and needs to be taken exactly as prescribed. ...Read more

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I stopped taking my medications over a month ago and have had no relapse, withdrawals, or any symptoms. How long until I can switch medications? I was previously on abilify, (aripiprazole) wellbutrin, and straterra.

I stopped taking my medications over a month ago and have had no relapse, withdrawals, or any symptoms. How long until I can switch medications? I was previously on abilify, (aripiprazole) wellbutrin, and straterra.

It depends: If you stopped taking your medications a month ago, I hope this was a mutual decision between you and your physician. I don't know what conditions you were being treated for, since these medicines could be used in different ways. Conditions do not have to relapse immediately for you to be in danger of that possibility. Your doctor is the best person to answer your question. ...Read more

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I take both Prozac and wellbutrin (bupropion) daily — what will happen if I do cocaine while taking these medications?

I take both Prozac and wellbutrin (bupropion) daily — what will happen if I do cocaine while taking these medications?

Meds & street drugs: Use of any illicit drug its self damaging to brain system makes life long irreversible changes in the neuronal circuitry. Combining with meds is never a good idea and can cause opposing effects that can be making mood and anxiety symptoms worse and at times difficult to treat. If you still need to use a substance to covet for mood and anxiety meds your current meds are not well talk to psychiayrst. ...Read more

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Smoking cessation I've heard that wellbutrin (bupropion) is used to help one quit smoking. How long is one generally on the medication?

Bupropion : Bupropion (wellbutrin) was developed and initially introduced in the United States as an antidepressant but was subsequently noted to reduce the desire to smoke cigarettes and shown in clinical trials to be effective in smoking cessation. It works best along with intensive behavioral support. Approximately 1 week of treatment is required to achieve steady-state blood levels of bupropion and treatment is typically continued for anywhere between 8 – 12 weeks. If you have not made significant progress towards abstinence by the seventh or eighth week of therapy, treatment should probably be discontinued. ...Read more

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I take Effexor (venlafaxine) and wellbutrin for panic disorder. What other treatments are best besides medications?

Talk therapy: Even with medication, I think it is a very goo idea to do some cbt talk therapy. That can help you feel more skilled (less helpless) in moderating or avoiding attacks. You may not need the meds if you are successful. Also, meditation and certain exercise programs can be a good support for correcting this disorder. I'm impressed by your interest in self-management. I bet you'll do well. ...Read more

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I am currently taking lexapro Wellbutrin (bupropion) and alprazolam. Is it safe to take vyvanse with these medications?

I am currently taking lexapro Wellbutrin (bupropion) and alprazolam. Is it safe to take vyvanse with these medications?

It may not be: Wellbutrin (bupropion) has a well-known potential side effect of producing seizures (usually in higher doses like 450mg/day and in seizure-prone individuals) and Vyvanse may compound that risk. I am not a fan of alprazolam use in most people, particularly those with depression. Sounds like your depression has been significant, and perhaps you should consider a second opinion from another psychiatrist. ...Read more

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What's the best medication for extreme snappiness, and extremely tired very irritable. I've tried Prozac, Wellbutrin etc.?

What's the best medication for extreme snappiness, and extremely tired very irritable. I've tried Prozac, Wellbutrin etc.?

Irritable: A medication is not the only way to fix this. Please think holistically. See doc to make sure you do not have medical issues such as thyroid or other hormone imbalances. How is your diet and exercise level? Are there decisions you need to make? Consider seeing a mental health pro for support and clarification. Peace and good health. ...Read more

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I'm taking lexapro Wellbutrin (bupropion) and alprazolam. Is it safe to take a vyvanse with these medications in my system?

I'm taking lexapro Wellbutrin (bupropion) and alprazolam. Is it safe to take a vyvanse with these medications in my system?

Caution: You already have significant drug interactions with the 3 meds listed. Adding Vyvanse plus Wellbutrin (bupropion) increases risk for seizures. Vyvanse plus Lexapro increases side effects of Vyvanse and risk for serotonin syndrome. Review these meds with prescribing doctor. You need close medical supervision to take these medications. I hope this helps. ...Read more

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I am on Wellbutrin (bupropion) and it was working really well, but this past month I've felt really horrible. Can anxiety/depression medications stop working?

I am on Wellbutrin (bupropion) and it was working really well, but this past month I've felt really horrible. Can anxiety/depression medications stop working?

See doctor: I'm sorry you're feeling worse. "Horrible" can't be assessed in this format. Does this mean feeling worse emotionally, have some recent upsetting events happened, do you have any physical symptoms as well? Best to review with prescribing doctor to reassess Wellbutrin (bupropion) dose or alternative med and consider seeing a mental health professional for support and guidance during this tough time. Take care. ...Read more

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Will a rash from wellbutrin (bupropion) go away? As my body gets used to the medication? Rash is minor and I started about a month ago drug is helping depression

Will a rash from wellbutrin (bupropion) go away? As my body gets used to the medication? Rash is minor and I started about a month ago drug is helping depression

Wellbutrin (bupropion) rash: Please tell your doctor immediately about the rash -- it may be an allergic response that will not go away. If there's any possibility other factors are involved (new laundry detergent? Exposure to other allergens? Etc) it can be confusing. I would call my doctor today and not repeat wellbutrin (bupropion) dosing until you speak with your doctor or the on-call physician. ...Read more

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My medication dosages were upped 24 hours ago and I have had a migraine ever since. Can these medications be causing it? Wellbutrin 100mg->150mg Abilify 5mg->15mg Vistaril 10mg->25mg

My medication dosages were upped 24 hours ago and I have had a migraine ever since. Can these medications be causing it?
Wellbutrin 100mg->150mg
Abilify 5mg->15mg
Vistaril 10mg->25mg

Side effects: Headache is a reported side effect of all of these medications. Suggest informing your prescribing doctor about your headache. You and your doctor can discuss a plan to address the problem. ...Read more

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Is there any new medications for depression that are not SSRIs or Wellbutrin, or Effexor (venlafaxine). Is there anything new? I feel like I've tried every med.

TheQuestionDepresses: Boy, that's a big question. First you say you've tried everything, but that must mean your doctor(s) have tried many prescription medications. Sorry about that. It's really tough to stay motivated, but you have to! There's a world of alternative therapies and approaches for this. Google it! Right now you have to stay active. It's always the next necessary thing to do. It's documented that exercise helps. ...Read more

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Is it true viibryd (vilazodone hydrochloride) causes seizures like wellbutrin does? I never had seizures bit don't want a medication that can cause one. How about brintellix?

Is it true viibryd (vilazodone hydrochloride) causes seizures like wellbutrin does?  I never had seizures bit don't want a medication that can cause one.  How about brintellix?

Viibryd (vilazodone hydrochloride) & seizures?: It's probably an oversimplification to say that viibryd (vilazodone hydrochloride) "causes" seizures. In some small percentage of the population, it can decrease seizure threshold. Although, it should be noted that most anti-depressants, albeit to widely varying degrees, decrease seizure threshold. The best thing to do is discuss your particular concerns & your risk/ benefit & side effect profile with your prescribing MD. ...Read more

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I am talking wellbutrin (bupropion) XL 150 mg for anxiety (gad) is this a good medication for anxiety also on therapy?

Wellbutrin (bupropion) is a: Great medicine for atypical depression. However, selective serotonin reuptake inhibitors are often the first go -to medications for anxiety disorders. ...Read more

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I'm concern for my 5 month unborn child I'm pregnant with. I've been constantly stress medication which is 40 milligram of Celexa (citalopram) and 250 milligrams of bupropion and in at night 50 milligram trazodone?

I'm concern for my 5 month unborn child I'm pregnant with. I've been constantly stress medication which is 40 milligram of Celexa (citalopram) and 250 milligrams of bupropion and in at night 50 milligram trazodone?

Concerned about you: The combination of these 3 medications is kind of risky, they can interact together causing irregular heart beats, you are almost maxed out on doses, why on bupropion? Is it for smoke cessation? If you are worried about your baby you shouldn't smoke to start with or be around smokers, I know it's hard to quit but much harder on your unborn child, celexa (citalopram) is cautioned in last trimester, c ur MD ...Read more

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Adding a dopamine medication such as latuda/wellbutrin to an ocd/bipolar patient--wouldn't this make the OCD worse?

Not really.: Latuda (lurasidone) is an antipsychotic. Sometimes ocd is so severe that it reaches psychotic proportions, that Latuda (lurasidone) can help. But it is not indicated for ocd itself. Wellbutrin is an antidepressant of the aminoketone group, a Dopamine agonist and norepinephrine reuptake inhibitor. It is not indicated for ocd but may help the depression in ocd. Neither drug can make ocd worse. ...Read more

Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more


Dr. Sanjiv Kaul
188 doctors shared insights

Zyban (Definition)

Zyban is an addiction reducing agent which is a ...Read more