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Doctor insights on: Bupropion Hydrochloride Extended Release Side Effects

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On viibryd (vilazodone hydrochloride) for about a month now, at a 20mg dose with wellbutrin. The side effects haven't lessened. What meds other than Lexapro should I try?

On viibryd (vilazodone hydrochloride) for about a month now, at a 20mg dose with wellbutrin. The side effects haven't  lessened. What meds other than Lexapro should I try?

Small suggestion: Many of my psychiatric colleagues have shared experiences with a medical food deplin, which when added to antidepressants improves the effects and does not add side effects. Discuss this with your doctor. ...Read more

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Dr. Alan Ali
781 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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How to deal with the side-effects of zyban (bupropion)?

How to deal with the side-effects of zyban (bupropion)?

Fairly mild: The side effects of zyban (bupropion) are fairly mild. Most common are a bit of dry mouth, blurry vision or constipation. You may get a little anxious early on. These mostly go away within 2-3 weeks. In high doses, it can cause seizures, though this is fairly rare (i haven't seen a case in 20+ years of using it). It can also, over months time slightly increase blood pressure & heart rate. ...Read more

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What are some common side effects from zyban (bupropion)?

What are some common side effects from zyban (bupropion)?

Fairly mild: The side effects of zyban (bupropion) are fairly mild. Most common are a bit of dry mouth, blurry vision or constipation. You may get a little anxious early on. These mostly go away within 2-3 weeks. In high doses, it can cause seizures, though this is fairly rare (i haven't seen a case in 20+ years of using it). It can also, over months time slightly increase blood pressure & heart rate. ...Read more

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What are the side effects of zyban (bupropion) one should look for?

What are the side effects of zyban (bupropion) one should look for?

See below: Mainly funky dreams and irritability. Also nausea. The depression and other stomach symptoms are from not smoking but cannot be overcome while on Chantix as this blocks nicotine. ...Read more

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What side-effects might you have when you start wellbutrin (bupropion) sr?

What side-effects might you have when you start wellbutrin (bupropion) sr?

Several possible: With wellbutrin (bupropion) sr you might experience dry mouth, nausea, headache, flushing, sweating, loss of appetite, difficulty sleeping, dizziness, strange taste in mouth, etc. You could also have ringing in the ears, fast heartbeat, agitation, and in rare cases, confusion. You should tell your physician about any of these side effects. Taken as prescribed, it should be a safe medication. ...Read more

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Took bupropion today for the first time, what are side effects i can expect?

Bupropion: You may not have any side effects at all. :-) however, possible ones include anxiety, dry mouth, irritability, restlessness, shaking, insomnia, headache. At high doses, susceptible people may expereince seizures. Your doctor will have assessed your history beforehand, and would not have prescribed it if seizures were likely. ...Read more

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Wellbutrin XL vs bupropion sr side effects?

Buproprion: Bupropion sr and wellbutrin (bupropion) xl are two different products with the same active antidepressant drug (buproprion) but they differ in the delivery rate in our system: the sr (slow release) and the xl (extra long). In my clinical experience, they are very similar, and the difference in side effect is the sleeplessness that could result from taking the xl formulation. ...Read more

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Does wellbutrin (bupropion) have fewer side effects than lexapro?

Different: Wellbutrin (bupropion) does not cause weight gain and it does not have sexual side effects. It does carry a small but increased risk for seizures and may be more likely to make anxiety worse among other side effects. ...Read more

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What are the side effects on wellbutrin and topamax (topiramate).?

What are the side effects on wellbutrin and topamax (topiramate).?

THE CORRECT ANSWER: Dr. Stein is correct in the adverse effects he lists. He is totally wrong in saying topamax (topiramate) is a mad drug, it has changed the lives of many of my patients with neuropathic pain and migraine headache. He also misstates what an ssri does...It prevents the reuptake of serotonin from the synapse, it does not deplete body levels of serotonin. ...Read more

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What's the differentiating side effects between Paxil and Wellbutrin?

Serotonin vs dopamin: Paxil, a serotonin med, will have more GI side effects- nausea, cramping, Bowel changes, since it has a short half life, if not taken regularly some ppl report 'withdrawals' that feel like electric impulses on the nerves. Wellbutrin, a dopamine med, will have more central/autonomic nervous system SE like headaches, bp changes, insomnia, moodiness. ...Read more

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Is it possible to feel the side effects of buproprion (wellbutrin, zyban) on the 1st day?

Yes, it is: It is not uncommon to experience drug effect on first day. Keep in mind that often early effects that you "feel" will change or go away as you continue to take the medication. Of course, allergic reactions (eg rash) is in a different category. If you experience allergic reaction, you should call / show your doctor. ...Read more

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I accidentally missed my dose of wellbutrin (bupropion) (150 mg). Any side effects from this?

Wellbutrin (bupropion): Depends on how long u have been on it, & what other medicines u take, but generally speaking, u should be just fine if you resume your daily dose. Missing just 1 dose is of no concern, but please do let your doc. Know. ...Read more

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Could someone possibly feel (side)effects of buproprion (aka wellbutrin/zyban) on the 1st day?

Yes: You may experience side effects right away. Therapeutic effects may take a while. ...Read more

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What happens when people occasionally drink too much alchohol on wellbutrin (bupropion)? Serious side effects? Thanks

What happens when people occasionally drink too much alchohol on wellbutrin (bupropion)?  Serious side effects?  Thanks

Seizures: It is not good idea to drink alcohol in excess with any medication meaning more than 1 or 2 drinks at a time.. One of the potential side effects of wellbutrin (bupropion) is seizures. Alcohol particularly alcohol withdrawal also can cause seizures. The potential for seizures is additive. ...Read more

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Is name brand wellbutrin XL more effective than generic (bupropion)? Taking generic but too many side effects and little effect on mood after 4 weeks.

Is name brand wellbutrin XL more effective than generic (bupropion)? Taking generic but too many side effects and little effect on mood after 4 weeks.

For some, yes: For all medicines sold in the us, the fda requires that the active ingredient in wellbutrin (bupropion) be equally present in brand name and generic products. However, each generic manufacturer might use different fillers or dyes in its formulation. Pharmacies buy generics in quantity, and might change suppliers from month to month. Some (not all) patients notice differences in their results. ...Read more

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I'm having strange side effects on wellbutrin (bupropion) xl, should I tell my doc?

I'm having strange side effects on wellbutrin (bupropion) xl, should I tell my doc?

Yes: Please contact your prescribing provider to address any reactions you might be having toward medication. Good luck! ...Read more

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Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more


Dr. Sandra Lora Cremers
182 doctors shared insights

Zyban (Definition)

Zyban is an addiction reducing agent which is a ...Read more