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Doctor insights on: Bupropion H Cl Side Effects

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Is bupropion HCl more effective than budeprion sr?

Is bupropion HCl more effective than budeprion sr?

Wellbutrin (bupropion): Same medicine except that the slow-release is longer-acting formulation. ...Read more

Dr. Alan Ali
757 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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What is the difference between budeprion XL and bupropion HCl XL?

What is the difference between budeprion XL and bupropion HCl XL?

Wellbutrin (bupropion): They are the same medicine, brand name called Wellbutrin (bupropion). There are the Slow release form (SR) & the Extended release form (XL). ...Read more

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How to wean off bupropion HCl XL 150?

Drop the dose : Tapering down simply means reducing the dose - so cutting to 100 mgm/day for a few days, then 50 mgm for a few days and then stopping but speak to your doctor about coming off. ...Read more

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Would sudden stop of bupropion HCl XL be bad?

Possible: All changes in use of meds should be carried out with your md's input and guidance. Sudden stopping of antidepressants can cause withdrawal symptoms especially if you are on a high dose. Stopping an antidepressant prematurely may trigger a relapse. Thank you for asking this important question. ...Read more

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How long does it take for bupropion HCl to start to work ?

How long does it take for bupropion HCl to start to work ?

Generally 3-4 weeks: Most antidepressants take 3-4 weeks to show an effect. The best results usually come with a combination of psychotherapy and medication, rather than just using the medication alone. ...Read more

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Is it actually true that changing from bupropion sr to bupropion HCl XL will cause me to gain weight?

Probably not: Weight gain in this transition is not commonly encountered by prescribers who have familiarity with both preparations of bupropion. Stay safe! ...Read more

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Hi I'm prescribed " Bupropion HCL XL 300" and wonder if it will show up positive for amphetamine?

Hi I'm prescribed " Bupropion HCL XL 300" and wonder if it will show up positive for amphetamine?

Yes, with some tests: Buproprion can show up as methamphetamine on routine drug screens. Tell the agency/person/department doing it that you are on it and they can do a more specific test that won't confuse the two. This works, unless you are on methamphetamines too! See http://www.ncbi.nlm.nih.gov/pubmed/21191682 where Gas chromatography could differentiate between the two. ...Read more

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I just had a severe reaction to bupropion HCl 300mg which required a visit to emergency room. I only took 1. Should I just stop taking it?

Bupropion AE: You don't mention what the reaction was or what you were prescribed bupropion to treat (smoking cessation? -- usually is XL 150mg. Depression?), or what the adverse effect you experienced was. Check the instructions provided to you by the ER. They should indicate what meds to stop or continue, and when you should see ur prescribing doc. If you can't find these, ring the ER & your doc. Be Well! ...Read more

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My arnp has me on 20 mg of Lexapro (escitalopram) 1x daily as well as bupropion HCl sr 150mg 2x daily. I'm reading they don't mix well? Should i wean off lexapro (escitalopram)?

My arnp has me on 20 mg of Lexapro (escitalopram) 1x daily as well as bupropion HCl sr 150mg 2x daily. I'm reading they don't mix well? Should i wean off lexapro (escitalopram)?

Not sure where : You read that. Lexapro or other ssri's are often combined with wellbutrin (bupropion) to help people who have combination of atypical depressive symptoms ; typical depressive sxs or anxiety disorders. This is usually a well tolerated combination. I would not recommend coming off of this type of medication without discussing with the provider. ...Read more

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Started taking bupropion hcl, have black tar stools, dirahia, and blood now when I go too bathroom, what could it be?

Not likely: While there are not enough data to know for sure, it appears that some SSRIs may be more likely to cause bleeding than others, but bupropion is not one of them. Bupropion can sometimes cause severe constipation and inflamed hemorrhoids what can lead to bleeding. ...Read more

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Wellbutrin (Definition)

Bupropion is an addiction reducing agent and an antidepressant which are both a ...Read more


Dr. James Krick
175 doctors shared insights

Zyban (Definition)

Zyban is an addiction reducing agent which is a ...Read more