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Doctor insights on: Bunion Ankles Joint Pain Elevated Sed Rate

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Sedimentation Rate (Definition)

Is the rate at which red blood cells sediment in a period of 1 hour. It is non-specific measure of inflammation. It is performed by placing anticoagulated blood sample in an upright tube (westergren tube) then measuring the rate at which red blood cells fall (in mm per hour). It is useful in diagnosis of some diseases, such as autoimmune diseases, for assessment of severity of ...Read more


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What can causs knee heel ankle toe pain fatigue headaches bloodwork fine except 7.5 CRP 320 pos ANA?

What can causs knee heel ankle toe pain fatigue headaches  bloodwork fine except 7.5 CRP 320 pos ANA?

Several things: There are several issues that can cause these symptoms. The ANA is a screening test for lupus but can be positive in numerous other diseases. See a rheumatologist to establish a diagnosis and determine an appropriate treatment. ...Read more

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Joint pain And high CRP What are some possibilities? Neg rf factor and normal ESR rate

Joint pain
And high CRP   What are some possibilities? Neg rf factor and normal ESR rate

? finding: Both CRP and ESR reflect inflammation but ESR is subject to more variations since it is affected by anemia , estrogen treatment etc. These two values usually correlate to each other and thus the discrepancy is puzzling. Talk to your rheumatologist about it. ...Read more

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Severe joint pain in hips feet toes hands fingers knees elbows morning stiffness daily 20 mg prednisone no help MRI no inflam ANA 1:320 help?

Severe joint pain in hips feet toes hands fingers knees elbows morning stiffness daily 20 mg prednisone no help MRI no inflam ANA 1:320 help?

Try DMSO: DMSO (dimethylsulfoxide)--aka horse liniment--is available at a health food store or feed/veterinary supply. For systemic inflammatory conditions as you apparently have, I suggest one tsp per day orally. It tastes terrible. Mix with a small amount of water, and chase it with something else to kill the taste. Major adverse effect is that you will "off-gas" the DMSO in your breath and sweat. ...Read more

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Chronic joint pain swelling. Ra factor 11.9, sed rate 7, ANA positive and high 1:160, ccp antibodies high 250, CRP 0.4, any ideas drs? Thanks.

Chronic joint pain swelling. Ra factor 11.9, sed rate 7, ANA positive and high 1:160, ccp antibodies high 250, CRP 0.4, any ideas drs? Thanks.

RAc: Joint pains and swelling with elevated anti ccp is suggestive of rheumatoid arthritis . Diagnosis can be substantiated by thorough clinical exam and x-rays .Ra responds well if caught early. ...Read more

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What conditions may cause backpain, shoulder pain, ankle pain, joint pain along with weight gain, an elevated ALT (75 U/L), and ANA positive once.

What conditions may cause backpain, shoulder pain, ankle pain, joint pain along with weight gain, an elevated ALT (75 U/L), and ANA positive once.

Many explanations: This constellation of symptoms is very non specific and could be due to one of several processes. Inflammation/autoimmune disease, infection, trauma or overuse, obesity, metabolic problems, medication induced,genetic disorders, excessive alcohol intake, vitamin deficiency, particularly vitamin D. The best course of action is to see or talk with a doctor to explore possibilities. Wishing you well! ...Read more

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Joint pain in hands hgb is 8.9 ESR 36, no RA factor. Pain under ribs on both sides, prolactin serum 45 pain in legs, knees nd soles aftr restng, what?

Joint pain in hands hgb is 8.9 ESR 36, no RA factor. Pain under ribs on both sides, prolactin serum 45 pain in legs, knees nd soles aftr restng, what?

Inflammation: Elevated ESR is a nonspecific indicator of inflammation. You are anemic, have multiple joint pains. Just because RA is negative does not mean you do not have some other type of arthritis or possible infection. You need to follow up with your doctor for further testing. ...Read more

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Bone pain ( hip, groin, knee, and now heel, both wrists, right shoulder) . Elevated pth, calcium in 24 hour urine, negative scan, normal calcium blood?

Rheumatologist : I recommend you see a rheumatologist for evaluation of tour joint complaints. A rheumatologist will review your history and perform a physical exam. Most likely, further testing would be done to help come up with a diagnosis. Once an accurate diagnosis is established, appropriate treatment would be initiated. ...Read more

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Can Lyme cause sinus tachycardia? Experiencing groin pain, joint pain, particularly hands & feet. RA screen pos, all other RA tests in normal range.

Can Lyme cause sinus tachycardia?  Experiencing groin pain, joint pain, particularly hands & feet.  RA screen pos, all other RA tests in normal range.

Lyme disease: Lyme disease especially when chronic may affect the heart. Patients can also have neurologic involvement such as a facial nerve or facial droop. Patient is may develop a chronic arthritis. It is reassuring that the test for rheumatoid arthritis is negative. There are newer tests that may be used to rule out any rheumatologic condition. I recommend that you see a rheumatologist. ...Read more

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Joint pain in knees,left ankle & left elbow. I'm 32 & my c-reactive was 1.4, RA factor <10, uric acid 4.7, sed rate 6, pos ANA 1:40 homogeneous. Clue?

Joint pain in knees,left ankle & left elbow. I'm 32 & my c-reactive was 1.4, RA factor <10, uric acid 4.7, sed rate 6, pos ANA 1:40 homogeneous. Clue?

Pain : It may be minor inflammation of the jts. Which does not produce positive blood tests. I would try an anti-inflammatory, Aleeve 400mg daily with food for 10 days. If this does not help I would see your physician again ...Read more

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Does low bone density causes joint pain all joints Rh ANA factor thyroid are normal?

Does low bone density causes joint pain all joints Rh ANA factor thyroid are normal?

Not bone density: Low bone density does not cause any symptoms unless you have a fracture due to osteoporosis, then there is pain. Pain in joints can be from osteoarthritis or other forms of arthritis. See your doctor or a rheumatologist for diagnosis and treatment of joint pain. ...Read more

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Could plantar faciitis, knees that hurt going down stairs or up, trigger fingers in both hands w/ swollen lumps in palms be related? Crp elev sed low

Could plantar faciitis, knees that hurt going down stairs or up, trigger fingers in both hands w/ swollen lumps in palms be related? Crp elev sed low

Plantar fasciitis : Is a common diagnosis for heel pain. When one combines the other conditions mentioned, there are autoimmune dissorders that come to mind. A very common autoimmune condition inclueds RA (rheumatoid arthritis) and the panus that could associated with it. Additional tests are indicated. See you physician for other tests. ...Read more

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What autoimmune diseases may cause raised ALT, ankle pain, chest pain, spine & shoulder pain without ANA, HLA B27 being positive?

What autoimmune diseases may cause raised  ALT, ankle pain, chest pain, spine & shoulder pain without ANA, HLA B27 being positive?

Not many: Sounds like you have already had a "work-up" for your symptoms (ANA. HLA B27 are not :common" tests The raised ALT may or may not be associated with your other symptoms. Do you have a liver problem? Hepatitis B, C often cause associated joint problems. Get this checked out by the same Health Care Provider who obtained the blood tests you mention Hope this helps Dr Z ...Read more

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Can osteoarthritis, rhematoid arthritis and fibromyalgia cause elevated CRP levels?

Can osteoarthritis, rhematoid arthritis and fibromyalgia cause elevated CRP levels?

Not so! Fibromyalgia: Fibro and osteoarthritis are non inflammatory! CRP is not elevated with these. If CRP is elevated, look elsewhere! ...Read more

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Joint pain/aches, tendonitis, mouth ulcers, hair loss, fatigue, swollen fingers, finger rash in summer. neg ANA slightly elevated RF. very frustrating?

Joint pain/aches, tendonitis, mouth ulcers, hair loss, fatigue, swollen fingers, finger rash in summer. neg ANA slightly elevated RF. very frustrating?

Understanding: These symptoms certainly seen in many rheumatic disease with lupus on the list. Many immune symptoms are frustrating but also can be treated. I certainly rec seeing a rheumatologist for a full evaluation and treatment if you have not gone yet. Please try to have patience since medications may take a few weeks to a couple months to be quite helpful but you will feel better. ...Read more

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ANA+, RF 18.4, norm sed rate, mildly achy/weak joints but no stiffness in a.m. H/o neck pain improved with chiro and PT. Any insight?

Need more informatio: your physician will need to do more testing and have you see a Rheumatology physician. the blood tests alone are not enough the make a diagnosis ...Read more

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Finger joint swelling/redness,fever,fatigue,back shoulder hip pain/stiff and muscle aches. ANA pos,RF neg,other tests normal. Possibilities?

Finger joint swelling/redness,fever,fatigue,back shoulder hip pain/stiff and muscle aches. ANA pos,RF neg,other tests normal. Possibilities?

Several things: In young women finger swelling,fever,stiffness,muscle aches ,other joint pain can be the onset of lupus,Rheumatoid arthritis (RA test does not have to be positive). Other less common connective tissue diseases and even some infections can do this. A Rheumatologist should be able to work this out.Not all tests are positive early. ...Read more

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Sir, my ESR is 34, rf, aso, ANA tests al are -ve. I ve joint pain in finger, knee & toe. Mild swelling in 3 fingers at distal proximal joint. Pls help?

Sir, my ESR is 34, rf, aso, ANA tests al are -ve. I ve joint pain in finger, knee & toe. Mild swelling in 3 fingers at distal proximal joint. Pls help?

?Psoriatic Arthritis: Do you have a history of psoriasis? The dip inflammation may be consistent with psoriatic arthritis. Sometime the joint swelling can precede any evidence of the skin disease. See a rheumatologist if you have not done so already. ...Read more

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Can untreated hypothyroidism cause excruciating joint pain, especially in the ankles. Can it cause sed rate and CRP to be high.

Can untreated hypothyroidism cause excruciating joint pain, especially in the ankles. Can it cause sed rate and CRP to be high.

No: It will not elevate the sed rate and crp. The joint pain of severe hypothyroidism is low grade and not excruciating. There is another cause and it isn't thyroid. See a rheumatologist. The one exception is an increased risk of pseudogout which can cause major pain but is unlikely to involve the ankles. ...Read more

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Joint pain in knees,left ankle & left elbow. I'm 32 & my c-reactive was 1.4, RA factor <10, uric acid 4.7, sed rate 6, pos ANA 1:40 homogeneous. Clue?

Pain : It may be minor inflammation of the jts. Which does not produce positive blood tests. I would try an anti-inflammatory, Aleeve 400mg daily with food for 10 days. If this does not help I would see your physician again ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Sed rate 65, anemeic, recently panic attacks, and lupus anticoluglant elevated ( 8.2) also severe joint pain?

Dr. Alan Ali Dr. Ali
2 doctors agreed:

Abnormal labs: Best to review results of lab with the physician that ordered them. ...Read more

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Why do I feel joint pain if my sed rate is normal?

Why do I feel joint pain if my sed rate is normal?

It is not specific: The erythrocyte sedimentation is a measure inflammation that is not specific to joint pain, so it is possible to have a normal "sed rate" and still have joint pain. Secondly, the sed rate is not the most sensitive measure of inflammation. The c-reactive protein is a measure that responds more readily to the presence and absence of inflammation for any reason. ...Read more

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I am 49 and found out my sed rate is 39. I have joint pain and swelling. I also have small fiber neuropathy. Is this something to worry about?

I am 49 and found out my sed rate is 39. I have joint pain and swelling. I also have small fiber neuropathy. Is this something to worry about?

See a Doctor: Joint pain and swelling is something that you should check with your doctor esp when the ESR is elevated as well. There are many details I do not know here -- which joint is one example... See your doctor or a rheumatologist. ...Read more

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What about a low sed rate? Lots of chronic fatigue, high hemoglobin and hemacrit, confusion, memory loss and now stiff body and joint pain.

What about a low sed rate? Lots of chronic fatigue, high hemoglobin and hemacrit,  confusion,  memory loss and now stiff body and joint pain.

Not a problem : There is no disease associated with a low ESR. An elevated ESR is a nonspecific indicator of inflammation. There are many possible of a high ESR--infection, malignancy, or autoimmune disease. ...Read more

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Ra for 13yr controlled w/methotrexate 25mg weekly since may 2005. Diffuse joint pain since aug., sed rate/crp normal, no swelling, ruled out neuropat

Ra for 13yr controlled w/methotrexate 25mg weekly since may 2005.  Diffuse joint pain since aug., sed rate/crp normal, no swelling, ruled out neuropat

Not clear yet.: A complete history and physical examination are appropriate for all patients presenting with polyarticular joint pain since this symptom may be the initial manifestation of a systemic illness. ...Read more

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Severe joint pain in hands and feet and morning stiffness. Sed rate is norm. So no inflammation. So why do they hurt?

Severe joint pain in hands and feet and morning stiffness. Sed rate is norm. So no inflammation. So why do they hurt?

Don't assume ...: That there is no joint inflammation because sed rate is normal. It's unclear from your note how long you have been experiencing severe joint pain; in the early stages of joint inflammation the sed rate may be normal and even the finding of joint swelling can be subtle. You are in the age group in which Rheumatoid Arthritis may occur. A more sensitive marker for inflammation is the CRP; ask MD. ...Read more

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Chronic joint pain swelling. Ra factor 11.9, sed rate 7, ANA positive and high 1:160, ccp antibodies high 250, CRP 0.4, any ideas drs? Thanks.

RAc: Joint pains and swelling with elevated anti ccp is suggestive of rheumatoid arthritis . Diagnosis can be substantiated by thorough clinical exam and x-rays .Ra responds well if caught early. ...Read more

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Penny has RA and is on Orencia (abatacept) and methotrexate. Recent increase in joint pain along with low energy. Blood work says high WBC and high SED rate of 50?

Penny has RA and is on Orencia (abatacept) and methotrexate. Recent increase in joint pain along with low energy. Blood work says high WBC and high SED rate of 50?

Rheumatoid Arthritis: can sometimes be a tough condition to treat. Methotrexate is an excellent medication for RA but sometimes may need dose adjustments or adjunct treatment. Increasing joint pain and low energy are possible signs that the rheumatoid is not under control. A visit to the rheumatologist or treating physician is needed. ...Read more

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I have been having lots of joint pain, tingling, and ringing in ears. Sed rate 30, CRP 2.5, cardio CRP 32.3, ANA negative. Could it be lupus or?

I have been having lots of joint pain, tingling, and ringing in ears.  Sed rate 30, CRP 2.5, cardio CRP 32.3, ANA negative.  Could it be lupus or?

Lab data: Cannot comment on lab tests removed from the clinical assessment of a patient have no access to examine and extract full medical history. Lupus is less likely with negative ana, but not impossible. See a rheumatologist. ...Read more

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What can cause low vitamin d , high sed rate positve ANA daily headaches fatigue joint pain slight vision chance and loss of balance?

What can cause low vitamin d , high sed rate positve ANA  daily headaches fatigue joint pain slight vision chance and loss of balance?

Make diagnosis: Those are a lot of things and they may or may not all be connected. Certainly with an elevated sed rate and a positiveana test are concerning for an autoimmune condition, such as lupus, would be a concern. I would encourage you to continue work up with a rheumatologist and ultimately the single or multiple diagnosis made will aid in treatment and prognosis discussions. Thank you. ...Read more

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Is there a neurological condition that causes joint pain? I have ra, pain in multiple joints since mid-aug. Sed rate/crp nml. Per RA md pain is "neuropathic, " prescribed neurontin-not working.

Is there a neurological condition that causes joint pain? I have ra, pain in multiple joints since mid-aug.  Sed rate/crp nml.  Per RA md pain is "neuropathic, " prescribed neurontin-not working.

Rhematoid arthritis: As an orthopedic surgeon who treats R.A. Patients( end stage usually for joint replacement ), i would say that by definition R.A. Pts . Have joint pain because of the very nature of their diagnosis; generally not neuropathic( diabetic , for example). In my experience a negative rf, ana, etc. Early on is more common than not... Prob. A good phy. Exam to confirm dx. And nsaids would be most helpful. ...Read more

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Dr. Stratos Christianakis
1,189 doctors shared insights

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