Doctor insights on:
Bun And Creatinine Levels In Dehydration
Concentration: Simplest way, if you have lets say 100 particles in 5 liter of fluid, the concentration is 20 per liter. If you now have only 3 liter of fluid, the concentration is now 33.3.
BUN/Cr > 20:1: Urea (BUN) is reabsorbed by the kidney; creatinine is not. In dehydration, as water decreases and urea is reabsorbed, the BUN rises. Eventually, the cr will rise, too (if dehydration continues), but it doesn't increase in magnitude as fast as the bun. The bun/cr ration is usually ~10:1...When it's greater than 20:1, this suggests dehydration.
May be helpful: There are many causes of an elevated BUN or elevated creatinine, and the ratio between them must be interpreted in the clinical context of each specific patient. What is commonly referred to as "dehydration" usually causes an increase in the BUN to creatinine ratio, but other significant conditions may cause a similar rise and need to be considered, especially if there is an acute illness involved.
See below: An elevated BUN with normal creatinine and a ratio of [generally more than 18-20] occurs most commonly in dehydrated individuals and is not a sign of kidney damage.It may also occur in in certain other conditions like bleeding in the intestines, artificial nutrition intravenously of Amino Acids and use of steroids.
BUN/Creatinine ratio: Blood urea nitrogen (BUN) is the breakdown of protein excreted via kidney. Creatinine is the muscle breakdown product also excreted by the kidney. BUN and creatinine can be measured by lab tests. Usually the BUN / creatinine ratio has to to be over 20 for a patient to be considered dehydrated or in "pre renal kidney failure.
CKD CHF patient on fluid 1L restriction BUN 53, Creatinine 2, going worse when on lasix (furosemide). at what BUN am I too dehydrated/cause for high BUN/C ratio?
My potassium is high but I'm not dehydrated. Bun/creatinine ratio is high and other electrolytes are borderline. What could be wrong?
Dehydration: Yes your potassium and your bun/creatnine ratio could be affected.
What does it mean if your creatinine level is too high 1.16 and your bun/creatinine ratio is very low at a 5?
Why do you ask?: Labs mean nothing in the absence of a clinical history. You might be a vegan bodybuilder. When I was lifting weights every day, my creatinine ran 1.6-1.8. The fellow-pathologists with whom I've discussed it think that reports generated by labs are causing overdiagnosis of renal disease (it's subscience -- "there's an adjustment for race because black people are more muscular.")See 2 more doctor answers
What is a bun/creatinine ratio? How is it calculated and if mine is 22 but my other levels are fine what should I do?
What are the actual: Numbers? BUN number divided by creatinine number. Normal range is 10-20. 22 may not be abnormal if individual levels of BUN and creatinine are normal. Discuss the numbers with your doctor at the next visit.
Healthy 35 yr old female w B/C ratio elevated at 23 with normal Bun and creatinine level of 16 (ref range 7-18) and 0.7. I did not drink much that day?
Tests, tests, tests: Tests results always have to be interpreted in a context. When they measure the temperature of the winner of the Boston Marathon 2 yrs ago it was over106 F. Was he very ill? NO! He had been using his bodies muscles at full output for over 2 hrs straight. The heat generated raised his body temp a lot and he soon cooled off. You hv to talk with yr doc or make a virtual consult.
Co-tango usually: The BUN is usually 10 times the creatinine. When the creatinine goes up, the BUN goes up similarly to roughly keep this proportion, in most kidney disease states. The notable exception is when the creatinine goes up say by 20% to 1.2, but the BUN goes up *5 to 50. This strongly suggests a pre-renal state, commonly dehydration. Mild elevations of BUN with normal creatinines aren't of concern.
Monitor for now: Normal levels for females range from 0.5 - 1.1. However, as we get older, our kidney function does decline and creatinine levels increase. Dehydration and certain medications/procedures may also cause a bump in creatinine levels. I'd recommend a medication review and follow up labs in 1-3 months to monitor your creatinine levels, unless you notice changes in your urine in the interim.
Actual values: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, if both creatinine and BUN are normal you do not need to worry about the ratio.
Need numbers: It would help to have the actual numbers. The doctor who ordered these tests would be in a better position to advise as s/he knows your health status.
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