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Doctor insights on: Bsn Cell Mass

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Hodgkin lymphoma,stage IIb, bulky. 130mm,after 8 cycle of ABVD, PET + , hypermetabolic mass and increase its size to 141mm! Why?Is Stanford V helpful?

Hodgkin lymphoma,stage IIb, bulky. 130mm,after 8 cycle of ABVD, PET + , hypermetabolic mass and increase its size to 141mm! Why?Is Stanford V helpful?

Jury not out: There is ongoing trial to answer your question but previous studies suggest ABVD superior. That said, factors such as radiotx and personal immune response to Hodgkin D need to be considered. Fail cases to conventional chemoradiotx appear to respond to immune therapy, ie. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma N Engl J Med 2015; 372:311-319. Confirm ur dx 1st step ...Read more

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Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Mesothelioma biopsy says 'portions of fibrous tissue infiltrated by malignant cells forming nests. tumor cells +'ve for CK7 and calretinin. prognosis?

Marker not prognosis: CK7 and calretinin are used to verify that the tumor is mesothelial in origin (versus adenocarcinoma of the lung). It does not provide information about prognosis. Factors associated with pleural mesothelioma prognosis include: functional status, blood counts, histology (epithelial best vs fibrosarcomatous poorest), and tumor size (degree of involvement of pleural cavity). Several new trials. ...Read more

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Is chemo required for an invasive carsinoma in situ stage 1b grade 2, 0.8 CM in size mastec done, fibroadipose and breast tissue, sentinel lymph clear?

Is chemo required for an invasive carsinoma in situ stage 1b grade 2, 0.8 CM in size mastec done, fibroadipose and breast tissue, sentinel lymph clear?

Maybe: With a node negative cancer. { i don't understand the invasive and in situ as they are apposite. } current recommendations are for genomic testing to see if the tumor has a high or low risk of recurrence. ...Read more

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Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more

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1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

Now benign: From your information it isa benign adenoma , hurthle cell are little larger pinkish cell , but have higher incidence of malignant transformation than follicular , to hurthle cell carcinoma , unlike follicular , it will spread to lung , bone etc, follow your doctor's advice. ...Read more

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Age 76, stg IV ovarian cancer, debulking surgery, 3 chemos. Ca 125 normal. Is lymphnode dissection advisable? Comment on quality vs quantity of life?

Age 76, stg IV ovarian cancer, debulking surgery, 3 chemos. Ca 125 normal. Is lymphnode dissection advisable? Comment on quality vs quantity of life?

Quality of life: In end stage cancer quality of life is essential but patient 's decision is equally important. 76 yr old could be very healthy 76 , in stage IV some do respond well to chemo, will have quality & comfortable , remaining part of life , so choice should be left to the person. Also to follow the advice of doctors , if unsure to take a second opinion , treating md will be glad to refer. ...Read more

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Marrow aspirate flow cytometry. Whats importance of the dominant markers in lymphocyte vs. blast gates? Eg. Lymph CD2~5~7~38 Blast 22~34~45~117~hladr

Marrow aspirate flow cytometry. Whats importance of the dominant markers in lymphocyte vs. blast gates? Eg. Lymph CD2~5~7~38 Blast 22~34~45~117~hladr

Exactly400Characters: I'm not here to answer.This is beyond my expertise. But I would like to remind you,& others,that we are restricted to 400 characters(not words,but individual letters,etc).I would suspect that a question like this would require some more information before someone would want to commit to an answer and,anyways,the person who ordered and/or did the aspirate should be consulted for definitive answers. ...Read more

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Mom diagnosed wi/stage IV non small cell lung cancer its mets to bones, a lymph node, pancreas. What is her chances of survival?

Mom diagnosed wi/stage IV non small cell lung cancer its mets to bones, a lymph node, pancreas. What is her chances of survival?

Tough: Not curable but treatable. Survival depends on several factors, performance status-meaning how she is doing and how many side effects. Also depends on how well and if she responds to chemotherapy. Hope this helps. ...Read more

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What are the chances of metastatic renal cell cancer in a nephrectomised patient with clear cell carcinoma (fuhrman grade 2)?

What are the chances of metastatic renal cell cancer in a nephrectomised patient with clear cell carcinoma (fuhrman grade 2)?

Need more info: Stage and grade are needed to estimate this risk. One can check nomograms dot org where a number of such risk calculators can be accessed. ...Read more

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Hi, What chances of cancer by doing Autologous Adipose derived stem cell treatment.Pls help.thanks?

Hi, What chances of cancer by doing Autologous Adipose  derived stem cell treatment.Pls help.thanks?

Not much: There isnt much but this depends on the context of why there is the transplant. It is used either in cancer http://www.wjgnet.com/1948-9366/full/v8/i2/161.htm or reconstructive surgery. In someone without cancer, they dont even do studies to evaluate risk since the risk is assumed zero. ...Read more

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A 14x6x6mm non-enhancing signal abnormality inferior to the basal ganglia, no high rcbv, te 135ms cho/naa ratio - 1.3: heterotopia? Low grade?

A 14x6x6mm non-enhancing signal abnormality inferior to the basal ganglia, no high rcbv, te 135ms cho/naa ratio - 1.3:  heterotopia? Low grade?

Serial Imaging : Your MRI could be consistent with low grade neoplasm or a benign finding. The best option in these cases where it is unclear is to follow the area closely with repeat MRI at say 3 month intervals. If this is benign it will stay the same. If it grows it is likely a neoplasm. ...Read more

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Enhanced CT kidney 2.7x2cm homogeneous mass arising close hilum left kidney predominantly low density rising from 33HU to 62 on enhancement. Cancer?

Enhanced CT kidney 2.7x2cm homogeneous mass arising close hilum left kidney predominantly low density rising from 33HU to 62 on enhancement. Cancer?

See Nephrology: The information given is from part of a CT scan. There is more information needed to answer your question. See the ordering physician for next steps in your medical care. The specialist that works in this area is called a Nephrologist. Or Kidney doctor. ...Read more

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What is cure rate for testicular mixed (ec + yolk) cancer stage iiia (few enlarged retroperit. Lymph nodes max 2.5 CM and two small lung nodes <6mm)?

What is cure rate for testicular mixed (ec + yolk) cancer stage iiia (few enlarged retroperit. Lymph nodes max 2.5 CM and two small lung nodes <6mm)?

Improving: Over all prognosis is pretty good due recent advances in chemotherapy used to be decimal couple of decades ago., approaching 90% . You have to speak to the oncologist , as the statistics constantly changing to better .Good luck. ...Read more