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Doctor insights on: Brittle Bone Disease

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Dr. Linda DiMeglio
71 doctors shared insights

Brittle Bone Disease (Overview)

Typical brittle bone disease is due to loss of mineralization of normal bone and can be diagnosed by regular x-rays. It is uncommon in men , in which case other diseases and conditions may be suspected, such as malabsorption, or other systemic disease. In women, it is common after menopause.


Dr. Linda DiMeglio
71 doctors shared insights

Brittle Bone Disease (Overview)

Typical brittle bone disease is due to loss of mineralization of normal bone and can be diagnosed by regular x-rays. It is uncommon in men , in which case other diseases and conditions may be suspected, such as malabsorption, or other systemic disease. In women, it is common after menopause.


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Living with Sickle Cell Disease (Checklist)

Keep doctor's appointments
Once
Go to lab appointments
Once
Keep oxygen up by maintaining low weight, no smoking
Once
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Hypermobile, poor healing, broken bones from cycle accidents. Need tests for brittle bone disease?

Hypermobile, poor healing, broken bones from cycle accidents. Need tests for brittle bone disease?

Collagen issue: Sounds more like a collagen issue. Unfortunately there not a treatment for poor collagen like there is for osteo-porosis. Still worth getting bone density, electrolytes, and hormones checked. (thyroid, para thyroid). ...Read more

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Living with Celiac Disease (Checklist)

Schedule a visit with a dietitian
Once
When eating out, inform your waitstaff you are intolerant of gluten
Once
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Can you tell me how is brittle bone disease being treated with stem cells?

Can you tell me how is brittle bone disease being treated with stem cells?

Clinical trials: Mesenchymal stem cells which can be isolated from bone marrow and other tissues are being infused into patients with osteogenesis imperfecta (oi) to see if they can cause normal bone growth. Active clinical trial here: http://clinicaltrials.Gov/ct2/show/nct01061099?Cond=%22osteogenesis+imperfecta%22;rank=1 more general info here: http://ghr.Nlm.Nih.Gov/condition/osteogenesis-imperfecta. ...Read more

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What is the treatment for brittle bone disease?

What is the treatment for brittle bone disease?

Symtomtic treatment: We have to treat people according the fractures they have. ...Read more

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Living with Crohn's Disease (Checklist)

Find a gastroenterologist and follow their treatment regiment
Once
Stop smoking
Once
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Is brittle bone disease genetic?

Usually: Osteogenesis imperfecta is a disorder of brittle bones. There is an abnormality in collagen 1 function, and so you are not able to make bones or other connective tissue structures correctly. This is why people often have "blue sclera" because the collagen is abnormal. Most cases are genetic, but a new mutation (not inherited) can be seen (about 35%). ...Read more

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Brittle bone disease ..Advice any treatment?

Brittle bone disease ..Advice any treatment?

Symptom relief: There is no cure since it is a genetic disease, but regular weight-bearing exercise to prevent bone loss, a diet rich in calcium and vitamin d, and sometimes even vitamin supplements will help. Bisphosphonates are a group of drungs that can increase bone density, but they have side effects. ...Read more

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Getting tested for brittle bone disease?

Getting tested for brittle bone disease?

Should be done: Osteogenesis imperfecta is an abnormality in collagen 1 function, and so you are not able to make bones or other connective tissue structures correctly. This is why people often have "blue sclera" because the collagen is abnormal. Most cases are genetic, but a new mutation (not inherited) can be seen (about 35%). There are 8 major types, and these can be tested for. ...Read more

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Will you grow out of brittle bone disease?

??: Not really sure what you mean if it is osteogenesis imperfecta the answer is no if it osteoporosis or it's lesser cousin osteopenia the answer is no so looks like the answer is no. ...Read more

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Living with Coronary Artery Disease (Checklist)

Take meds as prescribed
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Exercise daily as recommended by your doctor or trainer
daily
Limit meat, dairy, and fats as much as possible
Once
Eat whole grains only - not white bread
Once
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Can I get my baby tested for brittle bone disease?

Can I get my baby tested for brittle bone disease?

Severe cases evident: The more severe cases are evident before birth by ultrasound & or neonatal x-rays.Classification of lesser forms are based on age of first symptoms or specialized testing. My last case involved a skin biopsy and analysis of enzyme production in a specialty lab. Have your dr locate a genetics department at a med school or children's hospital if you want to pursue this testing. They can set it up. ...Read more

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What is the medical name for brittle bone disease?

What is the medical name for brittle bone disease?

Osteoporosis: In the elderly (mainly) we refer to loss of bone structure as osteoporosis. Untreated hypothyroidism can lead to bad bone issues. Vitamin d deficiency and calcium defiency can lead to a problem called rickets which is associated with weakened bones, rare in the usa, but common in some developing countries. Other disorders can be listed as well. ...Read more

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Treating Pelvic Inflammatory Disease (Checklist)

Ask for STD testing
Once
Have your partner get STD testing
Once
Take all of your medication exactly as prescribed
Once
Use condoms when having intercourse to prevent STD transmission
Once
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How is one tested for brittle bone disease and what is it?

Osteogenesis OI: There are at least eight recognized forms of osteogenesis imperfecta, check with your medical doctor he will guide though that for that. ...Read more

Dr. James Lin
97 doctors shared insights

Osteogenesis Imperfecta (Definition)

A condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more


Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more