Doctor insights on:
Bristol Myers Squibb Clinical Trials
American heart association medical journal just posted an article - small research study states that they have found new autoantibodys that are specific 2 pots patients, :) more research being done :)?
Research POTS: Yes more research is being done.Get a more detailed answer ›
Science is a method using simplicity, theories and then tests to see if the theory works; always. Clinical trials involve comparing one approach/choice/treatment option with another & checking outcomes. Key methodology is double blind & ideally cross-over design with outcome measures to be used determined in advance. Double blind: neither participants or people near them know ...Read more
Some crossover: Biotech companies mostly concentrate on biological molecules like antibodies as products for disease modification. Pharmaceutical companies mostly concentrate on chemicals that can be made in a laboratory. But pharm companies are constantly on the look for promising biotech companies to work with or buy to increase their product line. ...Read more
If tested for, yes: Paxil (paroxetine) is not typically tested for in general physiological screenings like cbc, blood chemistry, urinalysis, etc. However, if they're looking for specific drugs or medications they may do a screen focused on finding these. If involved in a clinical trial, it's very important to inform the staff of other drugs you're taking, since these may invalidate the results! ...Read more
I'm researching a medical condition. (worster drought)Are NIH & The Oxford Journal considered reliable sources?? Are there others worth looking into.,
Is there any clinical evidence showing euphorbia peplus (petty spurge, radium weed, milkweed) has any helpful effects treating basal cell carcinoma?
Milkweed for BCC: Basal cell carcinoma (bcc) is primarily treated surgically. When caught and treated early, it is almost always cured, and recurrence rates should be very low. If you have been diagnosed with a bcc, get it treated by your local surgeon or dermatologist. Don't risk a recurrence or growth of the tumor. ...Read moreSee 1 more doctor answer
Benicar/hct drug info sheet shows little differences in antihypertensive effect between dosages 40/12.5=16/10 while 20/12.5 =17/8. Would 20/12.5 be ok?
Response: Your BP goal should be <140/90. If you have heart disease, diabetes or kidney disease then it should be <130/80. Please go by response and use the smallest dose required to achieve the goals. Lifestyle modification with achieving ideal body weight, increasing exercise, watching salt intake, dash diet and moderation in alcohol intake will help decrease BP and minimize medication usage. ...Read more
In clinical report of LIPID PROFILE TEST i (male-31)have CHOLESTROL-195,Triglycerides is 478 and sr vldl - 95.6, sr hdl -28 ,tc/hdl - 6.9 , SSR L?
Hi risk pancreatitis: & cardiovascular disease. Big driver of Hi-Trigs is carbs/sugars in food: http://goo.gl/uDGIwD. Typical Chol. prior to 1st major heart attack in US is 170 mg/dL, yet Chol. is the wrong issue, commonly misleading. Get NMR lipoprotein test & optimize to abnormally healthy values for both LDL 9 ?mol/L, Trig to ...Read more
MGUS iggLambda .19 for 1yr. FLC lambda8.04 stable. Kappa drop<1 from 4.2 no ratio calculable.IGM 27 SPEPGammaGlob .63 Doc not avail SLE tooThoughts?
MGUS: There are multiple issues regarding your health. MGUS is actually the simplest. With spike at a concentration of 0.19 and stable, you are at no immediate risk. The risk of myeloma is about 1%/year, but it does require regular follow-up. See this site for info. http://www.mayoclinic.org/diseases-conditions/mgus/basics/definition/CON-20026422 ...Read more
Parkinson. Slowness movement, beginning state. 2 guide fr 2 doctors: 1st: sifrol 250; 2nd: trivastal 50mg, lioresal (baclofen) 10mg, artane 2mg. Which one better?
Critique: Trivastal, a newer Dopamine agonist, is not available in the usa, but might be a choice. Sifrol, pramipexole, is likely your safest and best starting drug. There is no role for lioresal, (baclofen) and Artane is literally "poison" and is not used in the usa. Choose the doc who recommended sifrol. ...Read more
What changes were made since 2008 in terms of medicare, medicaid & hmo/ppo insurance reimbursements of dme, mobility, bath safety & orthopedic items?
This is a great: Question and ive tried to do some searching to give a concise answer but i cannot find a study that isolates this data. If you go to cms website and drill down to search the term dme http://www.Cms.Gov/site-search/search-results.Html?Q=dme you see how hard it is to give a quick answer, ( have you read an article in hfn or elsewhere that gives this data? If so please share. ...Read more
Lower LDL-C goal: Wow! that's a pretty deep/involved question. Treating to new targets (tnt) was announced/published in 2005. The idea was to see if more aggressive treatment of cholesterol (aiming for lower goals) would improve outcomes. Indeed it appears that aiming for goal LDL <70mg/dl leads to lower risk of cardiac events in stable heart disease. Read more at http://www.Theheart.Org/article/399675.Do. ...Read more
A lab reported my ANA test result -ve, cut off rate: 1.117, sample rate: 0.198. They used immulite 2000 rai analyzer. Is it standard, reliable report?
It's just a lab: As a pathologist, i'm well-acquainted with the pitfalls of all ANA testing. The real decision is whether to treat your joint pain as lupus or one of its ana-positive variants. Many healthy folks have some ANA on board. The value that's returned from the lab is only one piece of the puzzle in working up rheumatologic disease. ...Read more
Below: Yes: There have been numerous studies over the years, that the dosage of vaccine in Pentaxim against Pertussis is low, that it is not able to protect humans from infection in the long run. A recent study by WHO also states that pertussis (respiratory disease, which spreads through contact) is on the rise again & is prevalent among 5+ years old children in the United States & Europe, where this vaccine has been adopted as part of the national immunization schedule. This vaccine has already been banned in developed countries, on WHO’s recommendation. ...Read more
Ok, except sometimes: Medicare part d drugs must be approved by the fda for sale in the us and available only by prescription, so are generally safe. Pharmacists get their meds from a network of distributors, so sometimes counterfeit or lower-quality meds illegally enter the supply chain. It is more likely to happen from asian factories, but counterfeiters are clever and can disguise where meds are originating from. ...Read moreSee 1 more doctor answer
Great question.: This is a complicated subject that people spend their entire careers on - what makes a good study/clinical trial? It depends on many things: what type of study is done, funding source, if the results are clinically significant or just statistically sig, how is the data analyzed, etc. If there's a particular study you see in the news, your doctor might be able to help clarify the take home points. ...Read more
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