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Doctor insights on: Brca Positive Breast Cancer

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Family history of breast cancer. Should i get brca testing?

Family history of breast cancer. Should i get brca testing?

Depends: Many people have a distant relative who had breast cancer late in life and that is not an indication for brca testing. There are certain criteria like very young breast cancer, male breast cancer, triple negative breast cancer before age 60, and others. Visit your family doc or gyn to see if you need a referral to a genetics health professional for testing. ...Read more

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Dr. Barry Rosen
1,336 doctors shared insights

Breast Cancer (Female) (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more


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Can all breast cancer patients carry the brca genes?

Can all breast cancer patients carry the brca genes?

No!: Many patients with breast cancer have no genetic predisposition or risk for breast cancer. However, there are several genetic markers which increase the risk of developing breast cancer over a person's lifetime. ...Read more

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What are the statistics of the brca/breast cancer gene?

Low incidence: Approximately 1 in 40 ashkenazi jewish women have a brca mutation. It also is seen in other isolated populations. A brca1 mutation can be inherited from a mother or father and is associated with up to a 80% lifetime risk of breast cancer and a 40 % risk of ovarian cancer options include increased surveillance chemo prevention or risk reduction surgery. ...Read more

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No one on family has any type of cancer except one great aunt breast cancer @ 71 I am Ashkenazic Jew should I get brca test?

No one on family has any type of cancer except one great aunt breast cancer @ 71 I am Ashkenazic Jew should I get brca test?

What will do with: the result? Given your family history, you are not likely to have BRCA gene. However, before getting tested, you need to ask yourself, what will you do with the results? Will you get bilateral mastectomy if it is positive? For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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My mom had lobular breast cancer at 54 and her paternal cousin had breast cancer at 48. Everyone is brca negative. Is this likely hereditary?

My mom had lobular breast cancer at 54 and her paternal cousin had breast cancer at 48. Everyone is brca negative. Is this likely hereditary?

Hard to tell...: ...without more info. BRCA 1 and 2 are not the only genes known to increase the risk for cancer and there are probably others we do not know anything about. Someone in the family (preferably your mom or her cousin) should visit a genetic counselor (if they have not yet done so) to see what other genes need to be tested if necessary and what else they can do to reduce their risk. ...Read more

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At what age should you be screened for breast cancer or cervical cancer if grandmother and aunt had each at early age in 30s/40s? Brca testing?;

At what age should you be screened for breast cancer or cervical cancer if grandmother and aunt had each at early age in 30s/40s? Brca testing?;

See genetics: Early age breast cancer might signal an inherited gene mutation such as the BRCA1 or BRCA2 gene, for which screening would begin around the age of 25. See a geneticist to assess risk for an inherited cancer syndrome. Cervical cancer screening begins by age 21. Family history may be a sign of shared environmental or lifestyle factors but inherited risk unlikely; tell your GYN the family history. ...Read more

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I have a history of breast cancer ...and am BRCA + i Recently noticed a dark brown spot on my upper gum it is irregular in shape. 1/4in..?ideas?

I have a history of breast cancer ...and am BRCA + i  Recently noticed a dark brown spot on my upper gum it  is irregular in shape. 1/4in..?ideas?

Yes! Get checked!: Anyone with a BRCA mutation is at risk for cancer, including melanoma. This can occur on the gums as well as the skin. The irregular shape and size of 1/4 inch makes your lesion suspicious and worthy of a biopsy, especially because you are BRCA positive. Don't wait... get checked! Hope that helps! ...Read more

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My grandmother had breast cancer and my grandfather passed from sarcoma both before the age of 40 (both dad's side) Would I benefit from BRCA testing?

My grandmother had breast cancer and my grandfather passed from sarcoma both before the age of 40 (both dad's side) Would I benefit from BRCA testing?

Yes: Having a second degree relative like a grandmother with breast cancer before the age of 40 is a red flag for possible BRCA. If your grandmother is living then she could be tested. If not, then your mother or father could be tested depending on which side of the family. If they do not have the gene then they cannot pass it on to you. Hope this helps. ...Read more

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If two members of my immediate family developed breast cancer, should I get tested for the brca gene?

If two members of my immediate family developed breast cancer, should I get tested for the brca gene?

Possibly: It's always better to test the family members who have breast cancer if possible. If they are first degree relatives (mother, daughter or sister) and one was under age 50 at diagnosis, you might meet criteria for brca testing. It's best to meet with a genetic counselor who can help guide you and your family so the correct people are tested. There are non-brca mutations as well. ...Read more

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My mother had breast cancer at 54, does this mean i'll get it? Is it still more likely i won't? Brca negative.

My mother had breast cancer at 54, does this mean i'll get it? Is it still more likely i won't? Brca negative.

Increased Risk: Having a mother with breast cancer doesn't mean that you will get breast cancer for sure. It does put you at increased risk of developing breast cancer. ...Read more

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Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Mark Hoepfner
1,028 doctors shared insights

Breast Carcinoma (Definition)

Breast carcinoma is a type of cancer where this uncontrolled growth of breast cells. Symptoms can include breast lumps, pain, and weight ...Read more