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Doctor insights on: Brca Gene For Breast Cancer

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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Dr. Barry Rosen
4,358 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is breast cancer inherited?

Is breast cancer inherited?

Sometimes.: It is estimated that approximately 10-15% of all breast cancers in the US are of the hereditary type. These genes can be inherited from either your father or your mother. If a woman inherits this gene, they have a 50-75% chance of developing breast cancer in their lifetime. These cancers tend to occur at any earlier age and may occur in both breasts. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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What is brac analysis for breast cancer?

What is brac analysis for breast cancer?

Genetic blood test.: As many as 10-15% of breast cancers in the US are believed to be hereditary. These are linked to mutations of a particular group of genes called the BRCA genes. There is a simple blood test to check to see if someone has a BRCA mutation. I advise my interested patients to see a genetic counselor to fully understand the ramifications of this test before having it done. ...Read more

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Is breast cancer hereditary?

Is breast cancer hereditary?

Sometimes.: It is estimated that 10-15% of all breast cancer cases in the us occur due to hereditary factors. This risk may be identified by doing a simple blood test to check for brca mutations. We generally advise testing family members with known breast cancers first before checking unaffected family. ...Read more

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Can all breast cancer patients carry the brca genes?

Can all breast cancer patients carry the brca genes?

No!: Many patients with breast cancer have no genetic predisposition or risk for breast cancer. However, there are several genetic markers which increase the risk of developing breast cancer over a person's lifetime. ...Read more

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Who should get breast cancer genetic testing?

Who should get breast cancer genetic testing?

Start w/affected pt: Pesonal and family risk factors assoc w/brca mutation: muliple fam members, bil breast cancer, male breast cancer, ovarian cancer, ashkenazi jewish heritage (specific founder mutations), diagnosis age <50 (dx age < 60 if er/pr/her2 - or triple negative). Both maternal and paternal history is important. ...Read more

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Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes. Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but quoting wikipedia: http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

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Are breast cancer and colon cancer linked?

Are breast cancer and colon cancer linked?

Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read more

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Is breast cancer autosomal dominant?

Is breast cancer autosomal dominant?

Well...: ...most breast cancers (80-90%) are not related to inherited traits so in those cases your question does not apply. However, the majority of high risk genes that cause breast and other cancers (like BRCA) are indeed transmitted as autosomal dominant traits. ...Read more

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Is ovarian cancer genetic?

Is ovarian cancer genetic?

Sometimes: Certain genotypes such as the brca mutations have a higher incidence of ovarian cancer. ...Read more

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Can breast cancer be inherited?

Can breast cancer be inherited?

The risk can: Breast cancer itself is not passed down, but the risk for developing breast cancer can be inherited. Mutations in genes called brca1 and brca2 can be passed from a parent to a child. These inherited mutations increase the risk of developing breast cancer dramatically. A person with a brca mutation may have a 50% or higher chance of developing breast cancer, but it's not 100%. ...Read more

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Are breast cancer and leukemia hereditary?

Some : Some cases of breast cancer genetic mutations brca i and ii , her 2 some breast cancer run in families. In leukemias not enough proof of genetic mutations as in breast cancer ( I do not know ) how ever leukemias run in family members, especially cll and AML , may not be genetic, could be environmental. ...Read more

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Family history of breast cancer. Should i get brca testing?

Depends: Many people have a distant relative who had breast cancer late in life and that is not an indication for brca testing. There are certain criteria like very young breast cancer, male breast cancer, triple negative breast cancer before age 60, and others. Visit your family doc or gyn to see if you need a referral to a genetics health professional for testing. ...Read more

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What is the hereditary breast cancer gene?

What is the hereditary breast cancer gene?

Mutations to: Brca1 and brca2 is associated with the most common inheritable breast cancer. ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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Who should undergo genetic counseling for hereditary non-polyposis colorectal cancer (hnpcc)?

Who should undergo genetic counseling for hereditary non-polyposis colorectal cancer (hnpcc)?

Family history: There are a number of different inherited defects that cause hnpcc. A person with strong family history of colon cancer, occurring at a young age should seek counseling. ...Read more

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
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Does breast cancer run in families?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Does breast cancer run in families?

It does in about 15%: Hereditary breast cancer occurs approximately in about 15% of cases. Majority of breast cancer occurs sporadically. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Is breast density a risk factor for breast cancer? Mammogram noted "extremely dense breasts".

Yes, breast density: is a risk factor for breast cancer. The relative risk for extremely dense breasts is about 4x the relative risk of patients with almost entirely fatty breasts, and about 1.6x the RR for "average" density breasts. Find out all you need to know at http://www.breastdensity.info/ ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


Dr. Mark Hoepfner
1,064 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more