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Doctor insights on: Brca 2 Pos Age 68 Is Mastectomy Recommened

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Brca 2 pos. Age 68 is mastectomy recommened?

Brca 2 pos. Age 68 is mastectomy recommened?

It is an option...: ...But not the only one. Any person with an inherited cancer trait or a strong family history of cancer should discuss their management with a specialist in cancer genetics. No such thing as one size fits all. Good news is that by knowing you have a mutation, you have the tactical advantage. Best to you. ...Read more

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Brca2 Gene (Definition)

This is a normal gene that makes a protein for basic cell functions. It was the second gene discovered that is often mutated in people at extra risk for breast cancer, and depending on the mutation these people often have increased risk of ovarian cancer as well. A person with a family history may be tested for the mutation and make ...Read more


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38 yo very strong FH breast ca, BRCA neg, Stage 2 IDC, 18 mo. s/p bilat radical mastectomy. No chemo. What is best f/u imaging/testing? Chemo?

38 yo very strong FH breast ca, BRCA neg, Stage 2 IDC, 18 mo. s/p bilat radical mastectomy. No chemo. What is best f/u imaging/testing?  Chemo?

Breast ca f/u: No follow-up imaging is indicated. History and physical is all that is required. imaging and blood test would be indicated if you were concerned for metastatic disease or a local recurrence. The additional of chemotherapy depends of pathologic stage including lymph node status, tumor biology and possibly the result of Oncotype testing. ...Read more

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32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy. What is survival rate?

32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy.  What is survival rate?

Need Clarification!: Are you sure your breast cancer was triple positive(or was it triple Negative)??? TCH is commonly used chemotherapy for triple negative, so please double check and let us know. Then we can give you survival figures. In general, small tumors(Stage 1 and stage 2) have very good survival rate and high cure rates. ...Read more

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What is considered psa recurrence? dad had <0.04 for 3.5 years after surgery, now has .13 psa. Gleason 6, pT2c N0 Mx. 10% prostate involved by tumor

What is considered psa recurrence? dad had <0.04 for 3.5 years after surgery, now has .13 psa. Gleason 6, pT2c N0 Mx. 10% prostate involved by tumor

Rising PSA is of con: His urologist can explain it best. Ask him if your father has not already been told what this means. Rising PSA in future check ups to be done every 6 months may confirm that he has PSA recurrence which is an early indicator that he has a few prostate cancer cells in his body producing PSA. He may need treatment if the next 2-3 PSA levels are higher and keeping rising higher. ...Read more

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Grade 1 invasive ductal carcinoma, 2 spots, family history, 47 years of age, small breasts. should I get double mastectomy?

Grade 1 invasive ductal carcinoma,  2 spots, family history, 47 years of age, small breasts. should I get double mastectomy?

It is your choice: Breast cancer can be adequately treated with a lumpectomy in most cases. So a mastectomy is not really necessary. But based on your breast size, your doctor can guide you best. Many women opt for reconstructive surgery at the same time as removal of your breast cancer. ...Read more

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Breast cancer, 2 tumors, one 1.4x1.7, the other .5. Biopsy states IDC, ER+, PR- and HER2 neg. Ki67 score 50 Treatment mastectomy, chemo and tamoxifen. What are your thoughs on treatment??? Patient is 32 years old

Breast cancer, 2 tumors, one 1.4x1.7, the other .5.   Biopsy states IDC, ER+, PR- and HER2 neg.  
Ki67 score 50

Treatment mastectomy, chemo and tamoxifen.  

What are your thoughs on treatment???  Patient is 32 years old

Curative: At 32, you have a long life ahead of you. By removing the breast with multiple tumors, you are saving yourself a lot of aggravation. There is nothing to keep a cancer from reoccurring in that breast! You did the right thing. Do not look back. You need to move forward! You are getting good treatment from your Provider! ...Read more

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Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more

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43 yo female 1.5 CM stage 1 breast ca, idc, er/pr+, node neg, lumpectomy with neg margins, no lvi, oncotype score 11. Chemo+rt+tamoxifen or no chemo?

43 yo female 1.5 CM stage 1 breast ca, idc, er/pr+, node neg, lumpectomy with neg margins, no lvi, oncotype score 11. Chemo+rt+tamoxifen or no chemo?

ARR - non-binary: Using adjvuant online! and making some assumptions for missing data: there is a 25% risk of relapse, tamoxifen absolute risk reduction (arr) is 9%, chemo arr 14%, combo (chemo+tam) is 18% arr. Combo-chemo is 18-14% is 4% absolute benefit from chemo. This low benefit is confirmed with oncotype DX recurrence score (low risk). So, the decision is non-binary, but rather about the arr benefit. ...Read more

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What are statistical odds for cancer returning in a 63 yr old woman 20 yrs after treatment for stage 1 breast cancer (lumpectomy, chemo, & radiation)?

What are statistical odds for cancer returning in a 63 yr old woman 20 yrs after treatment for stage 1 breast cancer (lumpectomy, chemo, & radiation)?

Low, but not zero.: First of all, congratulations on being a 20-yr survivor! it is impossible to give you a number or even a range without knowing more specifics about your cancer, however, the fact that it hasn't returned in 20 years certainly puts you in favorable statistical category. I suggest that you meet with your medical oncologist to discuss this, as well as any measures you can take to prevent a recurrence. ...Read more

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Is nipple sparing mastectomy safe for brca 2?

Is nipple sparing mastectomy safe for brca 2?

Yes: Many studies have been published demonstrating this option to be safe, both for treatment of breast cancer and prevention in women with brca mutations. No surgery will take the risk of subsequent breast cancer down to zero--there is always some breast tissue left behind, albeit microscopic. Therefore, it stands to reason that the more left behind, the higher the risk; yet, it remains quite low. ...Read more

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Fibroadenoma in 33 y old. report: oval, well circumscribed lesion 0.4 inch wide. birad 3. follow up 3 mths. no biopsy done. chance of being cancer?

Fibroadenoma in 33 y old. report: oval, well circumscribed lesion 0.4 inch wide. birad 3. follow up 3 mths. no biopsy done. chance of being cancer?

It is a benign tumor: Fibroadenoma is a common condition among the young females. The diagnosis is frequently made on physical examination and confirmed with a mammogram. A biopsy is not required unless it starts to grow and increase in size. So you can watch it for 6 months up to one year and note any change in size and have a follow up visit with your doctor at least once yearly. ...Read more

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Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done

Survival rate for triple neg receptors for early stage breast cancer after chemo treatment?  No lymph nodes involve, stage 1b, grade 2, mastec done

Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read more

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What are statistical odds of cancer coming back? 42 yrs old. Trip neg breast cancer, stage 3 C , axil & supra clav dist Mets. Dx last year, now NED?

What are statistical odds of cancer coming back? 42 yrs old. Trip neg breast cancer, stage 3 C , axil & supra clav dist Mets. Dx last year, now NED?

Very possible: Triple neg makes the lesion more aggressive and obviously not too responsive to hormonal therapy. Nodal disease extending to supraclavicular area is extent to which axilla can spread. No mets to occur from this site. Usually surgery, RT utilized. If NED, recurrence can only come from cells that might have spread from primary and now reside in marrow. If recurrence then chemo will be needed. ...Read more

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Success rate for mastectomy retaining flap and nipple no sentinel node invasion stage 1b measures 8mm, margins good except anterior 1.5mm? Must chemo?

Success rate for mastectomy retaining flap and nipple no sentinel node invasion stage 1b measures 8mm, margins good except anterior 1.5mm? Must chemo?

Tumor genetics: You could request a recurrence score which is a genomic evaluation of tumor cell gene s. 2 common tests in U.S. Are oncotype DX and mammaprint. ...Read more

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Is mastectomy good for an invasive & in situ lobular carcinoma, stage 1b, sbr grade 2, 8 mm in size with good margins except anterior margin 1.5mm ?

Concern: The 1.5mm margin anteriorly is the only margin that gives me concern. For patients undergoing lumpectomy, obtaining at least a 2mm margin is associated with a decreased risk of recurrence. It would not be usual practice to take you back to surgery for a re-excision of this margin, however. ...Read more

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Stage 1b IDC, grade 3 with 1 lymph node 1.9 mm (micrometastasis) and had mastectomy. Age 32, would u recommend radiation?

Stage 1b IDC, grade 3 with 1 lymph node 1.9 mm (micrometastasis) and had mastectomy. Age 32, would u recommend radiation?

Discuss: With your radiation oncologist and medical oncologist. Many people with micrometastases will benefit from radiaition. The also benefit from hormonal therapy if receptor positive. Good luck ...Read more

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Is chemo required for an invasive carsinoma in situ stage 1b grade 2, 0.8 CM in size mastec done, fibroadipose and breast tissue, sentinel lymph clear?

Is chemo required for an invasive carsinoma in situ stage 1b grade 2, 0.8 CM in size mastec done, fibroadipose and breast tissue, sentinel lymph clear?

Maybe: With a node negative cancer. { i don't understand the invasive and in situ as they are apposite. } current recommendations are for genomic testing to see if the tumor has a high or low risk of recurrence. ...Read more

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Is mastectomy really necessary for a stage 2 breast cancer patient?

Is mastectomy really necessary for a stage 2 breast cancer patient?

Depends: The choice between mastectomy (either one or both breasts) and lumpectomy depends on many factors including genetic issues, size of the cancer and of the breast, location, and many others. It is a choice to be made by both the surgeon and the patient after a thorough discussion. ...Read more

Dr. Barry Rosen
985 doctors shared insights

Mastectomy (Definition)

A mastectomy is complete removal of all visible breast tissue. Different variations exist, some of which spare some or all of ...Read more