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Usually: Most people with demyelinating disease of the brain (ms) do experience any of a wide variety of neurologic symptoms (e.g., visual changes, numbness/tingling, weakness), these may be intermittent. There are certainly cases in which a person has convincing MRI findings of ms but has no objective clinical signs or symptoms, though even these people are likely to develop symptoms at some point. ...Read more
Nerve fibers have a central axon insulated by myelin covering. Demyelination is damage to the myelin, and typically experienced in multiple sclerosis due to an autoimmune attack by lymphocytes, but may be seen also in hereditary leukodystrophies, acute encephalomyelitis, ...Read more
Several: There are hereditary problems called leukodystrophies, toxins such as glue sniffing can damage brain myelin, paraneoplastic events associated with cancers can have some effect, and of course ms as the best known cause. But sometimes, other disorders seem similar and can masquerade. ...Read more
No: No, Hashimoto's does not cause brain demyelinations. Hashimoto's is an autoimmune thyroid dysfunction which will eventually cause hypothyroidism. During initial stage of Hashimoto's, thyroid function may remain normal or transiently elevated with self resolution. But in long term, most patient with Hashimoto's will develop hypothyroidism requiring thyroid hormone replacement ...Read more
Undiagnosed nerve pain in both arms, legs, hands and feet. Lesions on brain, demyelination. All testing shows nothing?
Yes they can: More important than the number of lesions is what causes the demyelinating lesions. As an example, multiple sclerosis can cause symptoms from old lesions that remain even after the acute inflammatory attack ends. Talk with your neurologist about what to expect with CNS demyelinating disease. Good luck! ...Read more
In 2008 i was diagnosis with demyelination dz it had effected my brain @3%. Now as of my last set of tests in feb. 2013 the demyelination dz is at 27%. Why?
Need diagnosis: Not knowing much about you, i would guess that you could possess a form of multiple sclerosis, which is progressing, and you should be taking a specific medication. Do not understand the % terminology, but nonetheless, find a local neurologist, and confirm the etiology, and if indeed ms, this can be well controlled with newer potent agents. You should not delay. Let us know if we can help. ...Read more
Anywhere.: It can occur wherever you have nerves, so both in your brain, spinal cord, and your body. ...Read more
I have 13 small inactive demyelinations in the brain.Ms was excluded by a few neurologists. What could have caused them ?
Tests to exclude MS?: Tests that should be done to exclude ms include evoked potentials (visual, auditory, brainstem), MRI of the neuraxis (cervical and thoracic spine), and if unrevealing then a lumbar puncture to look for oligoclonal bands in the CSF but not in the serum. Only after those measures have been completed does one explore the more unusual causes. Good luck and well wishes. ...Read moreSee 1 more doctor answer
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