Doctor insights on:
Usually: Most people with demyelinating disease of the brain (ms) do experience any of a wide variety of neurologic symptoms (e.g., visual changes, numbness/tingling, weakness), these may be intermittent. There are certainly cases in which a person has convincing MRI findings of ms but has no objective clinical signs or symptoms, though even these people are likely to develop symptoms at some point. ...Read more
Nerve fibers have a central axon insulated by myelin covering. Demyelination is damage to the myelin, and typically experienced in multiple sclerosis due to an autoimmune attack by lymphocytes, but may be seen also in hereditary leukodystrophies, acute encephalomyelitis, ...Read more
Several: There are hereditary problems called leukodystrophies, toxins such as glue sniffing can damage brain myelin, paraneoplastic events associated with cancers can have some effect, and of course ms as the best known cause. But sometimes, other disorders seem similar and can masquerade. ...Read more
No: No, Hashimoto's does not cause brain demyelinations. Hashimoto's is an autoimmune thyroid dysfunction which will eventually cause hypothyroidism. During initial stage of Hashimoto's, thyroid function may remain normal or transiently elevated with self resolution. But in long term, most patient with Hashimoto's will develop hypothyroidism requiring thyroid hormone replacement ...Read more
Undiagnosed nerve pain in both arms, legs, hands and feet. Lesions on brain, demyelination. All testing shows nothing?
Yes they can: More important than the number of lesions is what causes the demyelinating lesions. As an example, multiple sclerosis can cause symptoms from old lesions that remain even after the acute inflammatory attack ends. Talk with your neurologist about what to expect with CNS demyelinating disease. Good luck! ...Read more
In 2008 i was diagnosis with demyelination dz it had effected my brain @3%. Now as of my last set of tests in feb. 2013 the demyelination dz is at 27%. Why?
Need diagnosis: Not knowing much about you, i would guess that you could possess a form of multiple sclerosis, which is progressing, and you should be taking a specific medication. Do not understand the % terminology, but nonetheless, find a local neurologist, and confirm the etiology, and if indeed ms, this can be well controlled with newer potent agents. You should not delay. Let us know if we can help. ...Read more
Anywhere.: It can occur wherever you have nerves, so both in your brain, spinal cord, and your body. ...Read more
I have 13 small inactive demyelinations in the brain.Ms was excluded by a few neurologists. What could have caused them ?
Tests to exclude MS?: Tests that should be done to exclude ms include evoked potentials (visual, auditory, brainstem), MRI of the neuraxis (cervical and thoracic spine), and if unrevealing then a lumbar puncture to look for oligoclonal bands in the CSF but not in the serum. Only after those measures have been completed does one explore the more unusual causes. Good luck and well wishes. ...Read moreSee 1 more doctor answer
Can having nephrotic syndrome aged 2-9 years old & relapse 12-14 or steroids, cause demyelination in the brain? If so, how?
Can having a ventricular septal defect correction operation (patch applied) in 1989, cause demyelination in my brain after? If so, how does it?
Separate problems: If you had successful vsd surgery and no problems afterwards, then this is unrelated. Brain injury can occur during surgery with cardiopulmonary bypass but typically these effects present differently than you describe and are not typical after vsd surgery. ...Read moreSee 1 more doctor answer
Got13small inactive demyelinations in the brain.Neurologists said not ms-demyelinations disposed different.Is pet scan enough to confirm or infirm ms?
MRI brain results Impression- there is cerebral atrophy with subcortical WMC, consistent wit microangiopathic disease, demyelination, or giliosis?
Covering the bases: That signal that is seen in patients who age is seen very frequently. Most of the time it is what has become known as microangiopathic disease or small vessel disease. Demyelination and gliosis come with a more notable history. Gliosis or scarring and demyelination also produces symptoms that MRI is useful for. Depends on why you had the MRI in the first place. The first entity more common than 2 ...Read more
Brain mri... I am 49 yrs old and i had an MRI and it shows enlarged opthalmic veins & foci demyelination. I also have punctate white matter. Help?
May not be related: The dilated opthalmic vein could be due to a cavernous sinus fistula among other possibilities and should be worked up further. This may not be related to the white matter hyperintensities. The other findings you describe could be due to multiple sclerosis and should be correlated with your clinical findings. ...Read moreSee 2 more doctor answers
Abnormalities in deep white matter regions. Is non specific & can be seen in the setting of demyelination migraine or vasculities MRI report, explain?
GENERIC ANSWER: I have no indication as to why your doctor ordered the mri, so my answer is general. The reading of the films lists a variety of possible explanations for the white matter lesions, including blood vessel problems, multiple sclerosis, and migraine, but could also include prior head trauma, smoking, and hypertension. Suggest a conference with your doctor to discuss relevance. ...Read moreSee 2 more doctor answers
MRI white matter disease in bilateral cerebral hemisphere; this may be seen with moderate chronic ischaemia versus inflammation/demylination. Worried.
Loss of nerve cover: Myelin acts as an insulation and covers nerves both in central and peripheral nervous systems, and the above term implies loss of myelin. This is often a description of multiple sclerosis, but is seen in the periphery in guillain-barre syndrome and chronic demyelinating immune neuropathies. ...Read more
Characteristic: Demyelination refers to damage to the coverings of the nerves in the brain and spinal cord, and is very characteristic of the inflammatory process that occurs in ms. This can also occur in children with hereditary leukodystrophies, and can be associated with acquired neurological disorders. The disease modifying drugs in MS are designed to control demyelination and many work well. ...Read moreSee 1 more doctor answer
I have been diagnosed with widespread axonal degeneration without demyelination, is this my fault?
Why?: I am sorry but i don't understand why you might blame yourself? Have you mistreated yourself or your body? ...Read more
Following a recent episode of a grey out in my vision I was given an mri, there is evidence of demyelination. What is that?
Wb-band 41 positive, dfm showed spirochetes and gemmas.Syphilis-negative.Can it be Lyme with only band 41 positive?Got inactive demyelination lessions
Possibly- more tests: A 41 band alone could signify lyme but is not enough to make the diagnosis. Unfortunately most labs don't do an adequate WB test- it's crucial to test the highly specific 31 & 34 bands & most labs don't. Ignenex does the best test. See http://www.Ilads.Org/lyme_disease/about_lyme.Html consider the controversial culture from advanced laboratory services: http://www.Medscape.Com/viewarticle/778482. ...Read more
Loss of insulation: Nerve fibers have a central axon insulated by myelin covering. Demyelination is damage to the myelin, and typically experienced in multiple sclerosis due to an autoimmune attack by lymphocytes, but may be seen also in hereditary leukodystrophies, acute encephalomyelitis, and inflam. Nerve disorders. ...Read more