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Doctor insights on: Braf Melanoma

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What causes a BRAF mutation in melanoma patients? Is it UV or is it family genetics?

What causes a BRAF mutation in melanoma patients?  Is it UV or is it family genetics?

Probably both: UV radiation and family genetics probably both play a role in BRAF genetics. To lower your risk of developing melanoma, it is best to limit your exposure to UV radiation and to know your family history. If your family history increases your risk, you should see your dermatologist a few times a year for skin cancer screening. Melanoma that is caught early is highly treatable. ...Read more

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Dr. Mike Bowman
905 doctors shared insights

Skin Cancer (Definition)

Skin is the largest and one of the most complex organs in the body composed of hundreds of different structures. Nearly any of these elements can degenerate into cancer. However the three most common are: basal cell, squamous cell and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use & ...Read more


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What is a melanoma?

What is a melanoma?

A type of skin cance: Melanoma is a type of skin cancer that arises from the pigmented cells (melanocytes) in the skin. In general, it is more malignant than the other two common skin cancer types (basal cell and squamous cell), but early melanoma has a good prognosis. Look online for the abcde for diagnosing melanoma. If you have a suspicious mole - have it checked out by a deramatologist. It could save your life! ...Read more

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How is melanoma diagnosed?

How is melanoma diagnosed?

Learn your ABCD's: Definitive diagnosis is made by biopsy. Melanomas are screened by the abcd's: a-asymmetry; b-irregular borders; c-different colors; d-diameber >6mm (size of pencil eraser). If you notice a mole with these characteristics, get it checked out asap. If you have a skin lesion which is growing, ulcerating, bleeding, or otherwise changing, get it seen as well for evaluation and possible biopsy. ...Read more

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What exactly is a melanoma?

Cancer of melanocyte: Melanoma is cancer of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. These cells predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can originate in any part of the body that contains melanocytes. ...Read more

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Is melanoma hereditary? How?

Is melanoma hereditary? How?

IN A SENSE: A positive family history of melanoma is a risk factor. So is hair-blonde or red-color and eye-blue or green-color, which of course you inherit. The biggest risk factor, though, is sun exposure. ...Read more

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How often is melanoma 1-2 mm?

Quite common: Most melanomas in the US are diagnosed when they have thickness of 1mm to 3mm) are diagnosed in about 30% of patients and carry an intermediate prognosis with a risk of recurrence between 15-30%. ...Read more

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Which symptom did you have of melanoma?

Which symptom did you have of melanoma?

Use ABCDE RULE: It's best to see a dermatologist but a good rule of thumb is the abcd guidelines a=asymmetry of lesion b=border is irregular c=colors are multiple and not consistent d=diameter is greater than 6mm e=evolution of lesion with changes and enlargement. ...Read more

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How should you know if you have melanoma?

How should you know if you have melanoma?

Skin cancer : Most skin cancers are the result of excessive sun exposure/tanning. Genetics play a strong role too. Any skin lesion that is changing size, color, shape or an area that does not heal is suspicious for skin cancer and should be evaluated by a dermatologist. ...Read more

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Is there any therepies available for melanoma ?

Is there any therepies available for melanoma ?

Yes: In addition to the surgery mentioned, there are new drugs for melanoma. One, called ipilumimab, is not chemotherapy. It is an immunologic therapy that was approved for use in 2011. It is the first drug to improve survival in stage IV melanoma, and some patients are alive 5-6 years after diagnosis with stage IV melanoma while on the drug. Have hope! ...Read more

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Dr. Travis Kidner
2,579 doctors shared insights

Melanoma (Definition)

Melanoma is a cancer of the melanocyte cells. Melanocyte cells determine the color of your skin. Although these cells are primarily found in your skin, they can also be found in the bowel ...Read more