Doctor insights on:
Borderline Lupus Anticoagulant
Clotting antibody: The lupus anticoagulant is a phospholipid antibody that can bind to cell membranes to make them sticky and increase the risk of blood clotting. It can occur transiently as the result of infections or medicines, or it can occur as spontaneous auto-antibodies or with autoimmune diseases. It may increase the risk of infertility or recurrent miscarriages. ...Read more
Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more
Part of lupus: You produce antibodies that can interact with the process of blood clotting to cause the blood to clot more easily than normal. This is part of the immunologic abnormalities associated with lupus in some affected individuals. ...Read more
Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more
None.: Lac is a laboratory finding of uncertain clinical significance. It predisposes to the development of autoimmune diseases such as lupus erythematosus, vitiligo, pernicious anemia, thyroiditis, inflammatory bowel disease, type I diabetes mellitus and addison's disease. If your rheumatologist has diagnosed you with a particular disorder, medications may be warranted on a clinical basis - not for lac. ...Read more
Blood test: Lupus anticoagulant is a blood test.Get a more detailed answer ›
Lupus anticoagulant: Yes, Discuss with your Dr and go to upgtodate. Com for review. ...Read more
Poorly Named Test: If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune disease should have done. ...Read more
No: No and it also occurs in people without lupus. ...Read more
Most, not all.: Lac is common in sle, but not universal. ...Read more
Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more
No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more
I have lupus anticoagulant and dr. Is wanting to put me on xorelto! I've read mixed reviews mostly against, & cost is a factor? What is your opinion?
Use caution: Xarelto is awesome if you listen to the manufacturer. Unlike coumadin, (warfarin) you do not require regular blood draws to evaluate effect. However, there is also no clear reversal agent if one does sustain a bleed. It can be a terrible situation when someone has a brain hemorrhage, etc, from relatively trivial fall. ...Read more
Impossible to say: It depends on many factors, not just on a diagnosis. If you are able to work, you are not disabled no matter what the underlying medical issues. ...Read more
No big deal usually.: Depending on whether you have a diagnosis of lupus or prior clotting problems, this may or may not be significant for your pregnancy. Studies show that most women with lac have normal pregnancies. Lupus anticoagulant (lac) is a laboratory finding and in and of itself not significant for predicting clinical outcomes. If you have systemic lupus erythematosus the plot thickens and you need to see mfm. ...Read more
Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more
Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more
I have lupus anticoagulant coagulopathy will it make your body hurt all over or is it something else.?
Hi Dr, I did lupus anticoagulant test. It shows appt (test)-ls 41.7 observed value. Lupus anticoagulant absent means? I have recurrent two abortion
Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. Thanks ...Read more
In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?
I tested positive for lupus anticoagulant when I was pregnant but do not now. My brother has as and my son is + for hlab27. Should I get tested again?
Different things: The + hal b-27 not related to lupus anticoagulant (la). The la needs to confirmed, especially if you have a history of clinical problems related to the la like blood clots in the legs, emboli to the lung, strokes, misscarriages, etc. Depending on the clinical picture you may need therapy - many only Aspirin for its anticlotting ability or stronger blood thinners. ...Read more
Lupus and pregnanacy: Sle or lupus is less likely to cause serious problems in pregnanacy if the disease is well controlled before conception, especially if you are cared for by both a rheumatologist and "high risk" ob. Also presence of lupus anticoagulant can be managed suceesfully. ...Read more
Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more
If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more
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