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Doctor insights on: Borderline Lupus Anticoagulant

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What is the lupus anticoagulant?

What is the lupus anticoagulant?

Clotting antibody: The lupus anticoagulant is a phospholipid antibody that can bind to cell membranes to make them sticky and increase the risk of blood clotting. It can occur transiently as the result of infections or medicines, or it can occur as spontaneous auto-antibodies or with autoimmune diseases. It may increase the risk of infertility or recurrent miscarriages. ...Read more

Dr. Boris Aronzon
533 Doctors shared insights

Blood Thinners (Definition)

Agents which slow ;/or break down blood clot formation in up to 3 different ways (they do not decrease blood viscosity; thickness.) (1) some inhibit platelet function (e.g. Aspirin, clopidogrel, etc.). (2) others interfere with some of the clot forming proteins (warfarin, dabigatran, rivaroxaban, etc.), (3) others stimulate the blood clot destruction ...Read more


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How does someone get lupus anticoagulant?

How does someone get lupus anticoagulant?

Part of lupus: You produce antibodies that can interact with the process of blood clotting to cause the blood to clot more easily than normal. This is part of the immunologic abnormalities associated with lupus in some affected individuals. ...Read more

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How many lupus anticoagulant tests are there?

How many lupus anticoagulant tests are there?

Many: There are tests for 3 forms of anticardiolipin antibodies, 3 forms of antiphospholipid antibodies, russell viper coagulation test and tests for specific components of coagulation and general tests (e.g., prothrombin time). ...Read more

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Do people with lupus have the lupus anticoagulant?

Do people with lupus have the lupus anticoagulant?

Not necessarily: Although many people with lupus have lupus anticoagulant not all do. And most people with lupus anticoagulant do not have lupus. Patients with lupus are more likely to develop the lupus anticoagulant than the general population so it is one "marker" for the disease. ...Read more

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What medicine do I take for the lupus anticoagulant?

None.: Lac is a laboratory finding of uncertain clinical significance. It predisposes to the development of autoimmune diseases such as lupus erythematosus, vitiligo, pernicious anemia, thyroiditis, inflammatory bowel disease, type I diabetes mellitus and addison's disease. If your rheumatologist has diagnosed you with a particular disorder, medications may be warranted on a clinical basis - not for lac. ...Read more

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What is the definition or description of: lupus anticoagulant?

Poorly Named Test: If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune disease should have done. ...Read more

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Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

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I was recently tested for lupus anticoagulant and it was postitive. Does that mean I have lupus?

No: Having a "lupus anticoagulant" just means there is an abnormality in your clotting mechanism that may make you m, ore easily bleed and, conversely slightly more likely to clot. While this feature may be seen in the disease lupus it does not mean that everyone with this factor has the disease lupus/ there are msany other features of the disease to look for. ...Read more

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I have lupus anticoagulant and dr. Is wanting to put me on xorelto! I've read mixed reviews mostly against, & cost is a factor? What is your opinion?

I have lupus anticoagulant and dr. Is wanting to put me on xorelto! I've read mixed reviews mostly against, & cost is a factor? What is your opinion?

Use caution: Xarelto is awesome if you listen to the manufacturer. Unlike coumadin, (warfarin) you do not require regular blood draws to evaluate effect. However, there is also no clear reversal agent if one does sustain a bleed. It can be a terrible situation when someone has a brain hemorrhage, etc, from relatively trivial fall. ...Read more

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Need information on circulatory lupus anticoagulant?

Need information on circulatory lupus anticoagulant?

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane. In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin! ...Read more

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Can I get disability for lupus anticoagulant disorder.

Can I get disability for lupus anticoagulant disorder.

Impossible to say: It depends on many factors, not just on a diagnosis. If you are able to work, you are not disabled no matter what the underlying medical issues. ...Read more

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What are dangers of conceiving if one has lupus anticoagulant and pcos?

Danger small but. ..: Pcos makes becoming pregnant difficult without treatment; pregnancy is usually ok though excess weight raises risk mildly; lupus anticoagulant requires careful study and may raise the risk of late miscarriage and require special treatment throughout pregnancy. ...Read more

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What nsaids can I take if I have the lupus anticoagulant?

What nsaids can I take if I have the lupus anticoagulant?

COX-1 active: Cox-1 active such as naprosyn, (naproxen) diclofenac, but avoid ibuprofen, as it reverses the benefit of aspirin. ...Read more

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How risky is it to get pregnant with lupus anticoagulant?

No big deal usually.: Depending on whether you have a diagnosis of lupus or prior clotting problems, this may or may not be significant for your pregnancy. Studies show that most women with lac have normal pregnancies. Lupus anticoagulant (lac) is a laboratory finding and in and of itself not significant for predicting clinical outcomes. If you have systemic lupus erythematosus the plot thickens and you need to see mfm. ...Read more

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Can you explain what a positive test for lupus anticoagulant means?

Can you explain what a positive test for lupus anticoagulant means?

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes. ...Read more

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What is the significance of a positive test for lupus anticoagulant?

Blood clots: You are paradoxically at increased risk of having blood clots. Discuss with your doctor. ...Read more

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Had a stroke due to lupus anticoagulant. How do I prevent another one?

Blood thinner: If it is confirmed that antiphospholipid syndrome (lupus anticoagulant is part of it) caused your stroke, then blood thinner such as warfarin (coumadin) may be of benefit. You need to consult a neurologist to make sure it is a right choice. ...Read more

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I have lupus anticoagulant coagulopathy will it make your body hurt all over or is it something else.?

I have lupus anticoagulant coagulopathy will it make your body hurt all over or is it something else.?

Something Else: Most likely it is something else other than the lupus anticoagulant causing your symptoms.....Such as the "common cold" or allergies instead of placing blame and focusing attention on something likely unrelated. ...Read more

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I recently had the test for lupus anticoagulant and it was postitive. What are the implications of this?

Depends on history: This test should always be confirmed by repeat and other related tests a prior history of multiple late pregnancy losses and /or unexplained clots make the test more ominous. ...Read more

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Hi Dr, I did lupus anticoagulant test. It shows appt (test)-ls 41.7 observed value. Lupus anticoagulant absent means? I have recurrent two abortion

Hi Dr, I did lupus anticoagulant test. It shows appt (test)-ls 41.7 observed value. Lupus anticoagulant absent means? I have recurrent two abortion

Lupus anti coag: Hello ~ people who have recurrent blood clots to the limbs can in some cases be lupus anti-coagulant positive as a cause and there is increased incidence of natural abortion or miscarriage in those cases. You are lupus anticoagulant negative so its irrelevant as a cause to any clotting disorder. Thanks ...Read more

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In 11/2014 I was hospitalized with bilateral PE. 3 lupus anticoagulant tests have come back positive, and he said it's primary. Does that mean APS?

Almost...: In my experience it can be primary, but other autoimmune disease must be excluded. IgM, followed by IgG anti -cardiolipin antibodies are the most problematic! This is important, since apart from anticoagulants, other drugs may be needed. ...Read more

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I tested positive for lupus anticoagulant when I was pregnant but do not now. My brother has as and my son is + for hlab27. Should I get tested again?

Different things: The + hal b-27 not related to lupus anticoagulant (la). The la needs to confirmed, especially if you have a history of clinical problems related to the la like blood clots in the legs, emboli to the lung, strokes, misscarriages, etc. Depending on the clinical picture you may need therapy - many only Aspirin for its anticlotting ability or stronger blood thinners. ...Read more

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Chance of conceiving if one has lupus anticoagulant?

Issue is safety: Issue is safety. Conception should not be an issue as long as the anticoagulant effect controlled and warfarin/coumadin not used. ...Read more

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What to expect with a diagnosis of purpura fulmicans and lupus anticoagulant?

What to expect with a diagnosis of purpura fulmicans and lupus anticoagulant?

Catastrophic APS Syn: You must get the full panel exam for an antiphospholipid syndrome like labs and good history and physical.
Aps can lead to arterial and venous thrombosis, frequent miscarriages and may need Coumadin (warfarin) - blood thinner. ...Read more

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Is it sle or lupus anticoagulant that causes pregnancy problems?

Lupus and pregnanacy: Sle or lupus is less likely to cause serious problems in pregnanacy if the disease is well controlled before conception, especially if you are cared for by both a rheumatologist and "high risk" ob. Also presence of lupus anticoagulant can be managed suceesfully. ...Read more

Anticoagulant (Definition)

Anticoagulants are any of a variety of drugs which decrease the body's ability to make or sustain blood clots. They fall, generally, into two categories. Drugs like Aspirin and clopidogrel (plavix) prevent platelets from forming the initial stages of a clot. Drugs like warfarin (coumadin) and dabigatran (pradaxa) block the later process ...Read more


Lupus Anticoagulant (Definition)

If your "lupus anticoagulant" test is positive, it indicates that your blood may clot more easily than it should (long story on the reason for the backwards name). It is important to know that this is only one of several tests for abnormal clotting that a person with an autoimmune ...Read more