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Doctor insights on: Bonemarrow Biopsy

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Is a bone marrow biopsy painful?

Is a bone marrow biopsy painful?

Yes and no: Any biopsy will be painful but in the hands of an experienced doctor and proper sedation (local novocaine) it can be a much more tolerable process. Pain killers such as tylenol (acetaminophen) afterwards for 24-58 hours can be a help too. ...Read more

Dr. John DeWolf
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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Can bone biopsy diagnose cancer?

Can bone biopsy diagnose cancer?

Usually a bone: Biopsy is done on a a bone with a symptom (pain) and an x-ray abnormalitity (dissolved bone. Lytic; sclerotic, bone, blastic) indicating metastasis or fracture. The biopsy can obtain tissue if the source is occult. A bone marrow biopsy is done to assess anemia, look for leukemia, and sometimes another marrow disorder. ...Read more

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Is bone marrow biopsy done without anesthesia?

Is bone marrow biopsy done without anesthesia?

Just for children: Young children will generally be put to sleep. The rest will at least get local anesthesia which is like novacaine over the hip. ...Read more

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4%plasma cells in bone marrow biopsy-how serious is it?

4%plasma cells in bone marrow biopsy-how serious is it?

Can be normal.: Up to 5% is normal as long as they are not "monoclonal" meaning derived from a cell. If monoclonal then a bone cancer called myeloma needs to be ruled out. If no bone disease, anemia, high calcium or kidney disease answer is MGUS, a pre-cancerous condition with low risk of progression (less than 1% per year). ...Read more

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What tests should be done frm bone marrow biopsy n aspiration slides?

What tests should be done frm bone marrow biopsy n aspiration slides?

Depends on purpose: How many tests can be done from blood? Millions. How many tests can be done from a bone marrow biopsy (BMB) specimen? Many? What tests should be done? It depends on 1) purpose for performing the BMB and 2) the findings the pathologist sees on morphologic examination of the aspirate & biopsy. Tests may include stains for iron or congo red (amyloidosis) as well as flow cytometry, cytogenetics, FISH. ...Read more

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What makes an a bone marrow biopsy abnormal?

Change in components: A bone marrow biopsy in a normal person will find the pattern of cells most often seen in a healthy person of that age.This would include red cells and their precursers (builders), white cells & precursers, platelet precursers & others. In illness, the pattern changes, and some or all may be abnormal. Tumor cells may take over every space& or few if any normal cells may be seen. ...Read more

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What is a bone marrow biopsy done for ?

Bone marrow biopsy: Hi, Bone Marrow biopsy is usually performed when a blood cell disorder is suspected, blood cell disorders are: Leukemia, aplastic anemia, multiple mylemoa and etc and some infectious processes. ...Read more

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What is lymph node excisional biopsy?

Sample lymph node: A surgeon cuts out the entire lymph node for pathological and sometimes microbiological examination. ...Read more

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Bone marrow test shows reactive erythroid hyperplasia .Does it indicate cancer?

No: Did you have a recent blood loss? Are you being treated for anemia? Reactive erythroid hyperplasia means the body is making more red cells because if perceived a lack of red cells. ...Read more

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Endometrial sqamous metaplastic cells endo biopsy has been done?

Endometrial sqamous metaplastic cells endo biopsy  has been done?

Please clarify: Pap smears and biopsies often show both squamous metaplastic endocervical cels and endometrial cells. Beyond a heads-up that hpv may be present, squamous metaplasia isn't a great concern. If you can rephrase what you are asking, someone here will be glad to help. ...Read more

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Will a bone marrow transplant cure bone marrow cancer?

Will a bone marrow transplant cure bone marrow cancer?

Yes: However it depends on the type of cancer, if it is in remission or not ,age of the patient and the type of donor. It also depends on the type of transplant, from self or another donor ...Read more

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Is liver biopsy painful?

Is liver biopsy painful?

It's not a bee sting: Despite using a local anesthetic, a liver biopsy is at best uncomfortable. A rather large gauge needle is used. Goes through the skin and muscle on the side of your abdomen and into the liver. Once there, the worse is over, pain wise. ...Read more

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Do bone marrow aspirations mean leukemia?

Do bone marrow aspirations  mean leukemia?

No: We do them for several reasons including evaluation for an abnormal cbc. Sometimes we are concerned about leukemia but the other reasons include the following: anemia, low platelets, staging of lymphoma, monitoring therapy. Hope this helps. ...Read more

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Can you tell me about bone marrow biopsy/aspiration report shows hypocellular marrow?

Can you tell me about  bone marrow biopsy/aspiration report shows hypocellular marrow?

Talk to doctor: This is a complicated issue to address in this forum. You should discuss it with your doctor and the two of you may wish to involve the pathologist who signed out the bone marrow report. ...Read more

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Are bone marrow biopsies ever false?

Are bone marrow biopsies ever false?

Rarely: Keep in mind that there is no such thing as 100% in life or in medicine. For every test we do, there is some chance (which may be very, very small) that the result will be incorrect. ...Read more

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Fnac report negative, but biopsy shows burkins lymphoma.Is it possible?Why?

Sampling error: Fine needle aspirate of lymph nodes are not ideal for ruling out abnormal findings. Especially, with lymphomas there may be areas within the ln that are not involved and sampling of these areas may be misleading. Excisional biopsy is the gold standard, as it allows for assessment of individual cells and architecture of lymph node and adequate tissue for specialty workup. ...Read more

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What does it mean if a bone marrow biopsy/aspiration report shows hypocellular marrow?

What does it mean if a bone marrow biopsy/aspiration report shows hypocellular marrow?

Hypocellular marrow: The normal bone marrow is a mixture of cells and fat. Hypocellular marrow means the marrow has fewer cells in the bone marrow space that is expected for that patient's age. There are many causes for this including nutritional deficiencies, bone marrow failure syndomes, pre-leukemia (myelodysplasia), prior chemotherapy, toxins and medications. ...Read more

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Hows stereotactic biopsy procedure done?

Hows stereotactic biopsy procedure done?

Computerized locati: The suspicious density, seen in x-ray but can not be felt , this area is located in two or more planes, marked, computer guided needle enters, at the marked site and takes biopsy, radio opaque, marker is placed for future reference, that biopsy was taken from correct location , then simple small dressing will be applied. ...Read more

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How are bone marrow biopsy and chromosome analysis different?

There is big differe: Bone marrow biopsy is done to obtain a pice of tissue to look under the microscope and find out if the blood formation is normal or abnormal. Chromosomes are not visible in the standard bone marrow biopsy. For this we need to culture the blood cells and capture the chromosomes when they are well formed just before the cells divide. This test takes a laboratory which can culture blood cells to see. ...Read more

Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more