Doctor insights on:
Bone Marrow Trilineage
Home of blood cells: The cells in your blood are born and reach maturity in the bone marrow. This is the very protected space in the middle of your large bones like your arms, legs, hips and back. Once the cells are mature, they are released into the blood stream where they travel throughout the body preventing infection (granulocytes, lymphocytes), supply oxygen (red cells) and prevent bleeding (platelets). ...Read moreSee 1 more doctor answer
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
HLA type: Every cell in your body has human leukocyte antigens (hlas) on the surface that act like a cell i.D. These allow your immune cells to recognize your cells as part of you and not foreign cells that need to be attacked. The bone marrow donor's hlas should match the patient's hlas as closely as possible so the donor's immune system doesn't attack the patient! hla is determined by a blood test. ...Read moreSee 1 more doctor answer
Tricky: Without an actual examination, I cannot give specific medical advice on your particular health, but an increased number of plasma cells in theory means a cancer of the bone marrow. There would be a LOT of other information you'd have to have before you could say that though. (appearance, activity of the plasma cells, what proteins they put out, genetics maybe, and many other features). ...Read moreSee 1 more doctor answer
Detecting diseases: Bone marrow tests are performed for many reasons, but the commonest ones are: detecting bone marrow involvement by a cancer - many cancers, notably lymphomas spread from their primary site to different organs of the body, including the bone marrow detecting cancers of the blood leukemias finding the cause of anemia. Bone marrow infiltration by other diseases ...Read more
See below: Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately 2.6 kilograms (5.7 lb). ...Read more
It is not too bad: There are 2 different ways bone marrow(stem cells) can be given to someone. One is quite simple and has literally no pain(it is called peripheral stem cell collection by apheresis). The other, more commonly used in the past, is true bone marrow donation which requires general anesthesia in order to draw the bone marrow from the hip bones and does cause more discomfort than the blood stem cell coll. ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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