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Bone Marrow Transplant Side Effects
In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more
We have a patient suffering from secondary myelofibrosis requiring bone marrow transplant. Donor is refusing on accounts of side effects ?
What is the question: Can you rephrase your question? What kind of side effects that the donor is afraid of. Perhaps, better understanding and communication about the procedure, the possible aes to the donor and answering the question will help the donor understand the situation. However, if the donor does not want to help- then nobody can force the donor. Other option is to use mud (matched unrelated donor) or cord blood.. Meanwhile, jakafi (ruxolitinib) can be considered for symptoms relief. ...Read more
Many possible: Possible side effects from a bone marrow transplant include: rejection of the donor marrow, graft vs. Host disease (donor cells attack the recipient), infections (bacterial, viral, fungal, etc...), mouth sores, stomach ulcers, diarrhea, liver disease, seizures, nerve pain, lung inflammation, hormonal deficiencies, osteoporosis, future cancers, etc... ...Read moreSee 1 more doctor answer
Bone marrow : The actual infusion of the cells does not hurt. The side effects of the chemotherapy and/or radiation therapy that are part of the preparative regimen of the transplant can be unpleasant. This can include nausea, vomiting, diarrhea, mouth sores, infections. ...Read moreSee 1 more doctor answer
No: A bone marrow or peripheral blood (pb) stem cell transplant (sct) is not painful. There are various "induction" treatments that depend on the type of cancer or disease to "condition" or get rid of the cancer (& normal) cells. A sct then "rescues" the bone marrow by returning self (autologous sct) cells or cells from another (allogeneic sct). The sct itself is similar to a blood infusion. ...Read moreSee 2 more doctor answers
Let me explain: 1-we have to have a donor who donate that, we do collect the bone marrow from him we call this step (harvesting) 2-we have to transplant this marrow to the recipient (patient receiving the bone marrow). 3-both involve special collecting method and method of delivery , done under anesthesia use some big needles to harvest. Some time require small surgery under anesthesia. ...Read moreSee 2 more doctor answers
Variable: The actual transplant which is the reinfusion of the bone marrow or stem cells is not painful. However there can be side effects to the radiation and/or chemotherapy used to treat the patient before the stem cell infusion. Depending on how the transplant is done those treatments can cause some unpleasant side effects including nausea, vomiting, abdominal pain and mouth sores among other things. ...Read more
Risky Business: Bone marrow transplantation (or stem cell transplantation) carries a less than 5% chance of mortality from complications when done in the autologous (self) setting. Allogeneic (from another donor) bmt however is riskier with about a mortality rate of 10-20% using related donors and up to 30% using unrelated donors because of graft-versus-host disease. ...Read moreSee 1 more doctor answer
Many!: Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. ...Read more
This refers to using chemotherapy and/or radiation therapy to treat patients and then replacing their bone marrow cells with their own stem cells (autologous transplant) or a donors stem cells (allogeneic transplant). Bone marrow transplant generally refers to using bone marrow cells but is often used when using stem cells collected ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
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