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Doctor insights on: Bone Marrow Diseases Organ Donation Programs

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Will a bone marrow transplant cure bone marrow cancer?

Will a bone marrow transplant cure bone marrow cancer?

Yes: However it depends on the type of cancer, if it is in remission or not ,age of the patient and the type of donor. It also depends on the type of transplant, from self or another donor ...Read more

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Dr. Ralph Layman
89 doctors shared insights

Organ Donation (Definition)

Organ donation requires surgical techniques that preserve the blood vessels and vital structures (e.g., ureter-kidney, bile duct - liver) and keeps the cells of the organ happy enough to function after blood flow is stopped and the transplant conducted. A living person may choose to gift an organ (or piece of an organ) through such an operation. A deceased person may gift multiple ...Read more


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Can bone marrow transplant affect fertility?

Can bone marrow transplant affect fertility?

Yes: Both male and female fertility can be affected with either temporary or permanent infertility resulting. Many patients undergoing transplant are already infertile due to the treatment already given for their cancers. There are strategies to preserve sperm or eggs before transplant if desired. ...Read more

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Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

One of the other: Stem cells can be obtained from 3 different sources: from Bone marrow of the Donor, blood of the donor or stem cells from umbilical cord. But we have to give an adequate number(Dose) of stem cells in order to have full protection. So combining them may only be needed because of inadequate number of stem cells from one of the sources ...Read more

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What are complications post- bone marrow transplant?

What are complications post- bone marrow transplant?

Many!: Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. ...Read more

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Why can't people with sjogren's donate organs, blood or bone marrow?

Why can't people with sjogren's donate organs, blood or bone marrow?

Autoimmune disease: Sjogren's is one of many autoimmune diseases. Organ donation would be very ill-advised since the likelihood that multiple organs are involved with autoimmune disorders is great. They also travel in clusters; for instance, where you have one autoimmune disorder, you are more likely to have another. While it's always awesome to want to donate organs and blood, donating disease is way less awesome :). ...Read more

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How is bone marrow donated?

How is bone marrow donated?

Under gen anesthesia: Donating bone marrow for transplantation entails a procedure called bone marrow harvesting. The donor is placed under general anesthesia and turned over to lie on his/her belly to expose the hip bones on the back. Multiple aspirations of bone marrow are collected (average about 1 liter) at adjacent sites on the hip bone on both sides until a particular number of cells are reached. ...Read more

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What lethal diseases are treated with bone marrow or stem cell transplants?

What lethal diseases are treated with bone marrow or stem cell transplants?

Many: The main lethal disease treated with stem cell transplants are hematologic malignancies such as leukemia, lymphoma and myeloma. Bone marrow failure (aplastic anemia) is also treated with stem cell transplants. Some life-threatening genetic disease can also be treated with a transplant. ...Read more

Dr. Liawaty Ho Dr. Ho
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How does aplastic anemia and bone marrow transplant relate?

Dr. Liawaty Ho Dr. Ho
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Aplastic anemia: Aplastic anemia is a condition where for some unclear reason the bone marrow fails to produce normal blood cells. It could be due to underlying genetic mutation plus environmental -i.e. Drugs, chemical agent, infection, etc. Immunosupressant agent has been used to treat aplastic anemia with some response. Allogeneic bone marrow transplant will be the treatment of choice to cure the disease. ...Read more

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What are risks of bone marrow donation?

What are risks of bone marrow donation?

Stem cell collection: Some times stem cells for transplant can be collected from an IV in your arm. This process involves a medication, g-csf, which increases the stem cells. This medication can cause flu-like symptoms and bone pain. Then the cells are taken, similar to giving blood or platelets. ...Read more

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How are organ transplants done?

How are organ transplants done?

See:: http://www.webmd.com/a-to-z-guides/organ-donation-facts

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How is a bone marrow transplant done?

Let me explain: 1-we have to have a donor who donate that, we do collect the bone marrow from him we call this step (harvesting) 2-we have to transplant this marrow to the recipient (patient receiving the bone marrow). 3-both involve special collecting method and method of delivery , done under anesthesia use some big needles to harvest. Some time require small surgery under anesthesia. ...Read more

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What's allogeneic bone marrow transplantation like?

What's allogeneic bone marrow transplantation like?

BMT from a donor: Allogeneic bone marrow transplantation (bmt) uses another person as the source of stem cells (bone marrow) as opposed to autologous bmt which uses the patient's own cells (usually frozen). Syngeneic bmt uses an identical twin for the donor. Allogeneic donors can be relatives (usually siblings) or totally unrelated. For more info on bmt check out: http://marrow.Org/. ...Read more

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Can someone with type 1 diabetes donate bone marrow or stem cells?

Can someone with type 1 diabetes donate bone marrow or stem cells?

Yes: The potential donor would have to be screened based on the entire health picture. Diabetes is not a contraindication to stem cell donation. ...Read more

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Sickle cell disease bone marrow transplant. Is that working out or not?

Sickle cell disease bone marrow transplant. Is that working out or not?

No clear results.: There is not level 1 evidence to show bone marrow transplant increases survival in patients with sickle cell disease. Although there are several reports with success a systematic randomized trial remains to be done. Bone marrow transplant is a procedure with multiple complications. After the procedure the recipient has to take meds for life. Cost/effective therapy analyses are not present. ...Read more

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Are bone marrow transplants painful?

Are bone marrow transplants painful?

Side effects: There are many effects which can be unpleasant like nausea, vomiting, diarrhea amd mouth sores. Depending on how the transplant is done the mouth sores can be severe and painful. There can be abdominal pain or bone pain in some patients. ...Read more

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How are recipients and donors matched for organ donation?

How are recipients and donors matched for organ donation?

Depends: Some are based on a combination of blood and tissue typing others are based primarily on tissue typing. Size of the individual's is also matched especially for pediatric patients. ...Read more

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Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more


Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more