Doctor insights on:
Bone Marrow Diseases Low Blood Count Anemia
Complex problem: It appears that your bone marrow is not making new blood, so you have anemia due to the failure of production. If you have pancytopenia then the problem is much more than anemia alone. Such situation are either due to leukemia or preleukemic conditions like Myelodysplastic syndrome(MDS). You need a blood specialist to help you sort it out and guide you further. ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
Check : With your arrow bank about their qualifications ...Read more
Leukopenia: Recent infection such as flu, chemotherapy, radiation therapy, aplastic anemia, hiv, lupus, hodgkin's lymphoma, cancer, typhoid, malaria, tb, sepsis, folate deficiency, copper & zinc deficiency, medications such as wellbutrin, (bupropion) depakote, lamictal, clozapine, minocycline, flagyl, interferone, arsenic toxicity. ...Read more
Aplastic anemia: Aplastic anemia is a condition where for some unclear reason the bone marrow fails to produce normal blood cells. It could be due to underlying genetic mutation plus environmental -i.e. Drugs, chemical agent, infection, etc. Immunosupressant agent has been used to treat aplastic anemia with some response. Allogeneic bone marrow transplant will be the treatment of choice to cure the disease. ...Read moreSee 1 more doctor answer
What causes Low Immature Granulocyte, High Neutrophil. High Hematocrit, High White Blood Cell Count? Have bone pain but rf factor shows normal.
See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual results. Why were the tests done? What symptoms do you have? It would require taking history, physical examination and may be more tests to settle the issue. Please see your doc. ...Read more
What could cause abnormally low levels of rbc, wbc, and platelets? Aplastic anemia, mds, leukemia have been ruled out via bm biopsy.
Infections-- but---: Much more detail is needed about your case. What's the age of the patient, comorbid states, medications, family history, environmental exposures, etc. This question is too important to have it answered correctly online- discuss it with your doctor who has all the facts in hand. ...Read moreSee 2 more doctor answers
Many: Depends on how low the count is and what other symptoms and signs are associated with it and what caused the low count. A common risk is propensity to infections. See this site for more info. http://www.mayoclinic.com/health/low-white-blood-cell-count/my00162. ...Read more
Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?
At least 2 problems: You realize that we can't diagnose you. With the very high serum ferritin and up-there serum iron, assuming the blood was not drawn during an acute illness, you have hemochromatosis until proved otherwise. How anemic you are, whether this is real macrocytosis, what your physical findings and other labs are are best known to your hematology consultation. Hope nobody gave you iron supplements. ...Read more
Unexplained high platelets (572), WBC (17.2), leukocytes, neutrophils, low hemaglobin. Bone marrow, jak2 and lupus test negative, ANA positive. Help?!
Reactive/ autoimmune: Discuss further with your hematologist. Certain conditions like iron deficiency , infection /inflammation vs autoimmune vs. Other solid tumor need to be ruled out. Need to check iron level, bcr/abl, imaging study like ct scan chest /abd/ pelvis will be needed. If you smoke - will suggest you to quit smoking., need to do work - up to find the anemia as well. If iron is low - GI w/u is needed. ...Read moreSee 2 more doctor answers
Is angioimmunoblastic t-cell lymphoma still treatable if in the marrow, anemia, low platelets, swelling?
T cell lymphoma: It is treatable but need careful supervision under the oncologist as chemo can be detrimental with low blood counts but sometimes that is the only way marrow can be cleared of lymphoma so lot of thinking needs to be done in selecting appropriate chemo for such patients. ...Read moreSee 1 more doctor answer
Be careful: "Small intestinal bacterial overgrowth" is usually a "pop", non-evidence-based diagnosis made by "independent medical thinkers." It's blamed for everything from rosacea to fibromyalgia, and you'll be offered a host of remedies but will never be "cured". If you haven't had a jejunal aspirate with a large number of bacteria to establish it, consider it unproven and seek evidence-based diagnosis/Rx. ...Read more
Numerous Causes: Platelets are a blood component necessary for hemostasis (cessation of bleeding); are produced in bone marrow; activated by blood vessel damage.There are numerous causes for a low platelet count: impaired production (bone marrow, genetic disorders); increased consumption (infections), increased destruction (autoimmune diseases), & more. Evaluation by your doctor is necessary to determine the cause ...Read moreSee 1 more doctor answer
Low MCV high red blood cells with abnormal morphology with low neutrophils and high lymphocytes counts?
Means nothing alone: In isolation from the patient story, lab tests mean nothing. This is especially true since we have no actual numbers. The low MCV and high rbc would make any physician think of a thalassemia, but it would be criminal to speculate further without knowing more about the person. If this is a you or a family member, you have a right and a duty to request your doctor's thoughts, or get consultation. ...Read more
No: Medullary sponge kidney is a very benign condition that does not disturb the function of the kidneys. It is mainly a radiological abnormality and can be associated with kidney stones of small variety usually in the kidney it self visible as small calcifications. It should not affect your bone marrow in any way. ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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