Doctor insights on:
Bone Marrow Disease Signs And Symptoms
Bone marrow disease: The symptoms are related to the abnormality of the bone marrow function -i.e. Decrease production of the blood cell counts-or increase level of blood cells counts if something supresses bone marrow function-anemia, decrease WBC and platelet can happen. -symptoms will include fatigue, infection, fever, bleeding. If the cell count is too much-clots, fatigue, feeling sluggish can happen. ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
It varies greatly: Bone marrow has lots of reserve, so it can be partly diseased, yet the body has no effect. But once the bone marrow is completely diseased or damaged, then the body will have all kinds of effects in the form of anemia (low hemoglobin), low WBC and low platelet counts and the complications of infections and bleeding as a result of low blood counts. ...Read more
No.: The very definition of a disease is that it is a condition which adversely affects health. So if you really have a disease in the marrow it's likely to make you feel sick sooner or later. ...Read more
Good question: Great question. Difficult to describe in 400 characters. Here is a great explanation: http://goo. Gl/rpdpp. ...Read more
Can they do a bone marrow biopsy even if the platelets seem fine but their is signs and symptoms of chronic leukemia?
I had a bone marrow examination showing an increase of plasma cells, 5.5%, with signs of anaplasia but no symptoms of any sort.
D/w your hem/onc: There's a condition that is called mgus- monoclonal gammopathy of unknown significant - which is essentially presented with presence of low level of monoclonal protein and abnormal plasma cells that are < 10%- and the absence of symptoms and myeloma related organ or tissue damage (predominantly renal, skeletal or bone marrow impairment.). From your limited info- it's perhaps a mgus. D/w your md. ...Read more
What is the prognosis for someone whose cold agglutin disease is suspected to have been caused by a virus, with negative for lymphoma bone marrow test?
Prognosis good: Cold agglutinins often come and go with a mycoplasma like chest cold. I trust this is not actually a cryoglobulin. ...Read more
Many: The main lethal disease treated with stem cell transplants are hematologic malignancies such as leukemia, lymphoma and myeloma. Bone marrow failure (aplastic anemia) is also treated with stem cell transplants. Some life-threatening genetic disease can also be treated with a transplant. ...Read more
Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?
Progressive: Yes, you described it well. New treatments are becoming available all the time, and they could extend your life! Get treated! ...Read more
No clear results.: There is not level 1 evidence to show bone marrow transplant increases survival in patients with sickle cell disease. Although there are several reports with success a systematic randomized trial remains to be done. Bone marrow transplant is a procedure with multiple complications. After the procedure the recipient has to take meds for life. Cost/effective therapy analyses are not present. ...Read more
What diseases cause bone marrow to produce the right cells but not fast enough in a 8 year old boy with low red/white cells, low platelets + neoutroph?
Viral: Viral diseases often. Blood disorders can cause the same in early stages. Some conditions are inherited. ...Read more
Will my bone marrow test show up for leukemia lupus etc, while I am on these IV treatments for my blood platelet disease?
I was wondering is a 25% increased ring sideroblasts in bone marrow a sign of bone marrow failure?
Can you tell me is a 25% increased ring sideroblasts in bone marrow a sign of bone marrow failure?
Seems high: Maybe genetic given your age. Have they checked your iron level? ...Read more
Please answer me. Is a 25% increased ring sideroblasts in bone marrow a sign of bone marrow failure?
Need more details: You need to tell us if you have your report of complete blood counts (CBC). If you can enlist all the numbers (HB, WBC and Platelet counts) we might be able to interpret your test results better. You also need to ask your doctor about the name of your disease/diagnosis??? ...Read more
Many: Bone marrow makes red cells that carry oxygen, white cells that protect you from infection, and platelets that stop you from bleeding. If bone marrow suppressed you will have anaemia-low red cells cause fatigue, infections since low white cells, and bleeding caused by low platelets. It can range from no symptoms-mild to severe. All depends on severity of the suppression. ...Read more
Myelodysplastia: (MDS) is classified according to the appearance of bone marrow cells. RARS (Refractory Anemia with Ringed Sideroblasts) is a relatively benign form, with abnormal red cells that show little rings of iron inside. It is not really a marrow failure (like aplastic anemia) because there are often plenty of cells in the marrow. Anemia can be severe and require transfusions or other therapies. ...Read more
Microscope: The cells from the marrow are analyzed under a microscope by a pathologist who can tell when the cells have abnormal growth and appearance. ...Read more
See below...: Myelodysplastic syndrome (mds) is a form of bone marrow cancer that is generally less aggressive than leukemia but still malignant. Refractory anemia with ringed sideroblasts (rars) is a form of mds that is generally low grade. In mds the bone marrow generally has high cellularity whereas in bone marrow failure (aplastic anemia, aa) it has low cellularity. Aa is usually not clonal (not cancer). ...Read more
Can a virus put you're bone marrow out of wack giving you the signs of aa then go away on it's own?
I have a 2-1/2 year old that keeps having high white blood counts. She has other symptoms to. Should she have a bone marrow test?
You need to: Discuss this with her hematologist. She has all her lab results and should be able to MAP out treatment plans and options and what is best for her. ...Read more
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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