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Doctor insights on: Bone Marrow Disease Signs And Symptoms

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Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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What are the symptoms of bone marrow diseases?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
What are the symptoms of bone marrow diseases?

Bone marrow disease: The symptoms are related to the abnormality of the bone marrow function -i.e. Decrease production of the blood cell counts-or increase level of blood cells counts if something supresses bone marrow function-anemia, decrease WBC and platelet can happen. -symptoms will include fatigue, infection, fever, bleeding. If the cell count is too much-clots, fatigue, feeling sluggish can happen.

Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more


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Can you please discuss bone marrow disease?

Can you please discuss bone marrow disease?

Unclear: The bone marrow is where the blood cells are produced. It can be affected by many conditions, malignant or not. "bone marrow disease" is to vague a term to make much of it.

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Describe the features of bone marrow disease.?

Describe the features of bone marrow disease.?

More detail needed: Bone marrow diseases are many and diverse. Can you be more specific in your question?

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Can bone marrow disease produce only minimal effects on the body?

It varies greatly: Bone marrow has lots of reserve, so it can be partly diseased, yet the body has no effect. But once the bone marrow is completely diseased or damaged, then the body will have all kinds of effects in the form of anemia (low hemoglobin), low WBC and low platelet counts and the complications of infections and bleeding as a result of low blood counts.

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Is it possible for bone marrow disease to gace no effect on your body?

Is it possible for bone marrow disease to gace no effect on your body?

No.: The very definition of a disease is that it is a condition which adversely affects health. So if you really have a disease in the marrow it's likely to make you feel sick sooner or later.

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Possible bone marrow disease if they can't find a cause for your anemia?

Possible bone marrow disease if they can't find a cause for your anemia?

Yes: Hello dpatrick8. I am not quite sure what you are asking, but if the cause of anemia is not obvious after a detailed history, physical examination, and blood testing, a bone marrow biopsy is frequently performed to determine the cause.

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After a patient has had bone marrow disease, how can isolating them help to prevent rejection?

Confusing: Can you restate your quetion? Are you talking about a bone marrow transplant? Isolation is required to prevent infections in people after bone marrow transplants, as the immune system is profoundly suppressed for a number of weeks and beyond.

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Describe the process of using adult stem cells to treating diseases like bone marrow diseases?

Describe the process of using adult stem cells to treating diseases like bone marrow diseases?

Good question: Great question. Difficult to describe in 400 characters. Here is a great explanation: http://goo. Gl/rpdpp.

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Can they do a bone marrow biopsy even if the platelets seem fine but their is signs and symptoms of chronic leukemia?

Can they do a bone marrow biopsy even if the platelets seem fine but their is signs and symptoms of chronic leukemia?

Yes/No: Bone marrow biopsy can be done in anyone provided there is a good reason to do so and it has possibility of giving useful information. Leukemia is best diagnosed with CBC first and then doing bone marrow only if there is something wrong in the peripheral blood counts (cbc).

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I had a bone marrow examination showing an increase of plasma cells, 5.5%, with signs of anaplasia but no symptoms of any sort.

D/w your hem/onc: There's a condition that is called mgus- monoclonal gammopathy of unknown significant - which is essentially presented with presence of low level of monoclonal protein and abnormal plasma cells that are < 10%- and the absence of symptoms and myeloma related organ or tissue damage (predominantly renal, skeletal or bone marrow impairment.). From your limited info- it's perhaps a mgus. D/w your md.

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What will a disease that affects bone marrow do to the body?

Many things: There are many diseases that affect the bone marrow and have different consequences, e.g., leukemia, anemia, low platelet count and bleeding, low white blood count and infections etc.

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What lethal diseases are treated with bone marrow or stem cell transplants?

What lethal diseases are treated with bone marrow or stem cell transplants?

Many: The main lethal disease treated with stem cell transplants are hematologic malignancies such as leukemia, lymphoma and myeloma. Bone marrow failure (aplastic anemia) is also treated with stem cell transplants. Some life-threatening genetic disease can also be treated with a transplant.

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Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?

Is myelofibrosis a terminal disease? Does it just keep progressing until all bone marrow is replaced by scar tissue that can't produce blood?

Progressive: Yes, you described it well. New treatments are becoming available all the time, and they could extend your life! Get treated!

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Sickle cell disease bone marrow transplant. Is that working out or not?

No clear results.: There is not level 1 evidence to show bone marrow transplant increases survival in patients with sickle cell disease. Although there are several reports with success a systematic randomized trial remains to be done. Bone marrow transplant is a procedure with multiple complications. After the procedure the recipient has to take meds for life. Cost/effective therapy analyses are not present.

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Sickle cell disease - is it curable with a bone marrow transplant?

Sickle cell disease - is it curable with a bone marrow transplant?

I do not know.: Most patients with sickle cell diseaes have a very benign manifestation of the diseas (trait) and they can live close to a normal life. E few percentage of this people has severe disease. I do not have experience with bone marrow transplant for sickle cell disease.

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Will my bone marrow test show up for leukemia lupus etc, while I am on these IV treatments for my blood platelet disease?

Will my bone marrow test show up for leukemia lupus etc, while I am on these IV treatments for my blood platelet disease?

Probably: I can't tell what blood platelet disease you have so I don't know what medications you are taking so it is not possible to definitively answer your question. Bone marrow is the best way to diagnose leukemia but is not a good test for lupus.

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I was wondering is a 25% increased ring sideroblasts in bone marrow a sign of bone marrow failure?

RARS: That is a lot. At your age, one can think of too much iron or a hereditary sideroblastic anemia. Rare to have a myelodysplasia at your age. The youngest person I saw was 45 years old. Hope this helps.

Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


Dr. Michael Dugan
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