Doctor insights on:
Bone Marrow Density Test
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
How can I perform density separation of mononuclear cells from bone marrow by using ficoll hypaque?
That is: A good question, but maybe not appropriate for this forum. ...Read more
Bone marrow tests are performed for many reasons, but the commonest ones are:
detecting bone marrow involvement by a cancer - many cancers, notably lymphomas spread from their primary site to different organs of the body, including the bone marrow
detecting cancers of the blood leukemias
finding the cause of anemia.
Bone marrow infiltration by other diseases ...Read more
Just as it sounds: Inconclusive means no conclusion can be given. It can be negative or it can be positive, but just not seen from the sample obtained. You may need another repeat study. Talk to your doctor who did the test to weigh the benefit vs risk of repeat testing. ...Read more
No they do not: But they do check you and examine you to make sure that you are healthy and do not have any serious sickness, diseases or major health issues. ...Read more
Hi docs, do you think it's adviseable to go through a bone marrow test because tc/dlc count is rising?
What?: What do you mean by tc/dlc count? If you mean total leukocyte count (TLC) then the answer is "possibly;" it depends on the differential breakdown of types of leukocytes and which are high. If it is neutrophils no. ...Read more
Terminal Deoxynucleotid Transferase what is this is there a normal range? I know it was found in bone marrow test..
Terminal transferase: Terminal transferase (TdT) is a template independent polymerase that catalyzes addition of deoxynucleotides to the 3' hydroxyl terminus of DNA. Protruding, recessed or blunt-ended double or single-stranded DNA molecules serve as a substrate for TdT. This molecule is a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells during mAb gene recombination. ...Read more
Yes: Of course. Drug use is extremely unhealthy. Why pass that on to someone who has a lowered immune status? ...Read more
I have a 2-1/2 year old that keeps having high white blood counts. She has other symptoms to. Should she have a bone marrow test?
You need to: Discuss this with her hematologist. She has all her lab results and should be able to MAP out treatment plans and options and what is best for her. ...Read more
Depends on purpose: How many tests can be done from blood? Millions. How many tests can be done from a bone marrow biopsy (BMB) specimen? Many? What tests should be done? It depends on 1) purpose for performing the BMB and 2) the findings the pathologist sees on morphologic examination of the aspirate & biopsy. Tests may include stains for iron or congo red (amyloidosis) as well as flow cytometry, cytogenetics, FISH. ...Read more
Bone marrow suppression...Progressively lower counts of red...White & platlets. 3 CBC tests all wotse in 60 days. Implications?
What is the cause: You need to go to see a hematologist to help you find out what is going on. There are so many things that can give you the problems. Blood works and bone marrow biopsy have to be done. Implication of havng low blood counts would depend on why and how severe/how low the blood levels. Go to see your doc and discuss more about this. ...Read more
What is the prognosis for someone whose cold agglutin disease is suspected to have been caused by a virus, with negative for lymphoma bone marrow test?
Prognosis good: Cold agglutinins often come and go with a mycoplasma like chest cold. I trust this is not actually a cryoglobulin. ...Read more
My son has had a platelet count of below 20 for 4 months. Should I push for a bone marrow test to find the cause?
What kind of blood test would my hematology dr. Order to see what's wrong with my blood instead of a bone marrow test?
Hierarchy of tests: Usual approach is to do a complete blood cells count and performa microscopic examination of the blood smear, the latter may be done by a pathologist. Depending on the findings, symptoms, and signs, other tests may be selected, e.G, flow cytometry, antibody testing, dna testing, and a bone marrow. Each test has its own place and there is no test instead of bone marrow. ...Read more
87 year old man no symptoms has been diagnosed with pancytopenia is it safe for him if they perform a bone marrow test considering his age? Worried
Safe: The opposite is unsafe, doctors need to get to the root of the problem, wish you both wellness ...Read more
I was just told that my bone marrow biopsy showed I have a 3rd set of chromosome 8. I have none of the clinical features. Is it possible the test is?
Trisomy 8 in marrow:
This abnormality is not associated with any specific disease, since patients
can have different clinical features, such as leukemia, polycythemia vera, and several other blood disorders. It's been suggested that the trisomy
may be a secondary rather than primary event in the development of the disease. It's different than trisomy 8 as a primary genetic event-w/ fetal development problem etc. ...Read more
I am under a haematologist at the moment for pancytopenia, and have had a bone marrow biopsy done, but the test has been inconclusive and has been crushed? What does this mean? Does it mean the biopsy is inadequate? Because I was told I may have to have a
No answer yet.: In a biopsy, the term inconclusive would be used to describe a result that is not independently and reliably diagnostic of the disease process under consideration. The biopsy may have to be done again, perhaps with a larger sample. ...Read more
My son is having a bone marrow test to find the cause of a low platelet count for 7 months. How do they collect the bone marrow?
Several choices: The skin over the testing area is injected with numbing medicine after it is cleaned and sanitized. The infant is usually provided with a form of conscious sedation to decrease their reaction to the event. A thick short needle with an angled bevel is inserted in either the tibia below the knee or the pelvis until the doc feels it enter the bone. The bone marrow is withdrawn into a syringe. ...Read more
I am suffering from low platelets count. My platelets persists between 50000 to 60000. Apparently I have no problem. Bone marrow test shown no problem?
My blood test for jak2 was negative but blood counts are still rising would you recomend bone marrow biopsy?
Yes: Jak2 testing is supportive of certain myeloproliferative diagnsoses, but the clinical decision to pursue the bm biopsy will be driven by the extent and pace of rise and your symptoms. ...Read more
Is there any condition that could cause both neutropenia and hypothyroidism? All orderedblood tests and bone marrow biopsy came back normal/negative.
Unrelated: Hypothyroidism is very common condition, so it is not uncommon to have other conditions that can coexist independent of each other. Neutropenia is often caused by bone marrow damage of some kind or other, although on rare occasions it can be congenital (since birth, cause unknown). The degree of neutropenia matters. So you should give us all the numbers of your CBC...such as WBC count & Neutrrophil ...Read more
Can someone who had a positive skin test for TB, 20 years ago give blood or bone marrow? But never had tb.
Check with your doc:
Usually no problem.
But check with your doc, especially if you have not taken medication to protect you against tb.
There are 2 billion people with a positive test, world wide. ...Read more
Would reviewing the bone marrow n aspiration slides by a better pathologist give a clearer picture how to fish tests help in myeloma?
2nd opinion can help: Never hurts to get your results verified by another doctor. ...Read more
Will my bone marrow test show up for leukemia lupus etc, while I am on these IV treatments for my blood platelet disease?
Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more
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