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Doctor insights on: Bone Marrow Cancer Multiple Myeloma

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Will a bone marrow transplant cure bone marrow cancer?

Will a bone marrow transplant cure bone marrow cancer?

Yes: However it depends on the type of cancer, if it is in remission or not ,age of the patient and the type of donor. It also depends on the type of transplant, from self or another donor ...Read more

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Dr. Barry Rosen
4,348 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is aml cancer cured by getting bone marrow transplant?

Is aml cancer cured by getting bone marrow transplant?

Yes, but...: Depending on the age of the patient and characteristics of aml, a bone marrow transplantation may be warranted in order to cure a patient. However, in some situations, some subtypes can be cured with chemotherapy alone. ...Read more

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Are bone marrow transplants painful?

Are bone marrow transplants painful?

Side effects: There are many effects which can be unpleasant like nausea, vomiting, diarrhea amd mouth sores. Depending on how the transplant is done the mouth sores can be severe and painful. There can be abdominal pain or bone pain in some patients. ...Read more

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What are complications post- bone marrow transplant?

What are complications post- bone marrow transplant?

Many!: Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. ...Read more

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How dangerous is a bone marrow cancer myeloma?

How dangerous is a bone marrow cancer myeloma?

Very: Multiple myeloma a plasma cell cancer could be very dangerous in some , in others ( the lucky ones ) the diseases can run for years. Have to speak to the treating oncologist good prognostic signs are higher albumin, lower beta 2 microglobulins, , plasma cell dna showing not having high risk chromosomal abnormalities. ...Read more

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Do bone marrow aspirations mean leukemia?

Do bone marrow aspirations  mean leukemia?

No: We do them for several reasons including evaluation for an abnormal cbc. Sometimes we are concerned about leukemia but the other reasons include the following: anemia, low platelets, staging of lymphoma, monitoring therapy. Hope this helps. ...Read more

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Can stem cell transplants cure multiple myeloma?

Can stem cell transplants cure multiple myeloma?

Remission: Multiple myeloma is treated classically with chemotherapy and autologous stem cell transplantation. Both modalities can put the disease on remission and prolong life substantially. I personally do not offer allogeneic stem cell transplant for multiple myeloma unless on clinical trial or under very stringent circumstances. Multiple myeloma remains an incurable but very treatable disease. ...Read more

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How bad is multiple myeloma with 40% abnormal plasma cells in bone marrow?

How bad is multiple myeloma with 40% abnormal plasma cells in bone marrow?

Depends: The number of plasma cells is not the only determinant of prognosis. Are there bone lesions on x-ray? Is kidney function normal? Has there been a response to therapy? Many patients with 40% plasma cells at diagnosis can do well for years. ...Read more

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Are bone marrow biopsies ever false?

Are bone marrow biopsies ever false?

Rarely: Keep in mind that there is no such thing as 100% in life or in medicine. For every test we do, there is some chance (which may be very, very small) that the result will be incorrect. ...Read more

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Dr. M. Jan Dr. Jan
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How are bone cancer and cancer of the bone marrow different?

Dr. M. Jan Dr. Jan
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How are bone cancer and cancer of the bone marrow different?

Big difference: Bone cancer is the cancer of bony part of the bone and cancer of the bone marrow is the cancer of blood. ...Read more

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What lethal diseases are treated with bone marrow or stem cell transplants?

What lethal diseases are treated with bone marrow or stem cell transplants?

Many: The main lethal disease treated with stem cell transplants are hematologic malignancies such as leukemia, lymphoma and myeloma. Bone marrow failure (aplastic anemia) is also treated with stem cell transplants. Some life-threatening genetic disease can also be treated with a transplant. ...Read more

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Is leukopenia the symptom of bone marrow cancers like leukemia?

Is leukopenia the symptom of bone marrow cancers like leukemia?

Sometimes: Leukopenia (low white blood cell count) can be a symptom of bone marrow cancers like leukemia or myelodysplasia. There are many other less serious reasons to have low white blood cells too. ...Read more

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What's allogeneic bone marrow transplantation like?

What's allogeneic bone marrow transplantation like?

BMT from a donor: Allogeneic bone marrow transplantation (bmt) uses another person as the source of stem cells (bone marrow) as opposed to autologous bmt which uses the patient's own cells (usually frozen). Syngeneic bmt uses an identical twin for the donor. Allogeneic donors can be relatives (usually siblings) or totally unrelated. For more info on bmt check out: http://marrow.Org/. ...Read more

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Are stem cell transplants for multiple myeloma effective?

Are stem cell transplants for multiple myeloma effective?

Yes.: Autologous stem cells transplants (from yourself as donor when in near remission) result in improved progression free survival and probably overall survival. Allogeneic transplant (from someone else) is more complex, and many would consider it experimental. Although the procedure may cure the disease, there are significant complications and risks that may offset the benefits. ...Read more

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Are bone marrow biopsies and aspirations risky?

Low risk: There is always risk involved in any procedure. Some have greater risk than others. Generally speaking, bone marrow biopsies are low risk, but your hematologist would be the best person to assess whether the risk outweighs the potential benefit, which is the real question. ...Read more

Dr. Lynne Weixel
125 doctors shared insights

Kahler Disease (Definition)

I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more


Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more