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Doctor insights on: Bone Marrow Cancer Multiple Myeloma

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How will my doctor know if I have multiple myeloma? 

How will my doctor know if I have multiple myeloma? 

Labs, xrays: There are a series of blood and urine tests that will give the doctor a good idea if you have the disease. These are usually followed by x-rays looking for tell-tale signs of myeloma and a bone marrow test which would identify the cancer cells themselves. ...Read more

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Dr. Scott Keith
113 doctors shared insights

Kahler Disease (Definition)

Kahler disease is also known as Multiple myeloma. I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more


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What is the definition or description of: multiple myeloma?

Plasma cell cancer: Multiple myeloma is a cancer of plasma cells (pcs). Pcs are the specialized b lymphocytes that produce antibodies. When there is a cancer or one (mono-) clone (= monoclonal, m) pc population they can product m-proteins. Symptoms include crab - hypercalcemia, renal (kidney) insufficiency, anemia, bone disease; also infection and pain. More: http://www.Cancer.Net/cancer-types/multiple-myeloma. ...Read more

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Which groups are most frequently affected by multiple myeloma?

Blacks in US: Twice the incidence in african americans than caucasians. Some families have a higher incidence. ...Read more

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My father died about 5 years ago from multiple myeloma. I was the bone marrow donor for his transplant. I am an only child and am wondering about my risk factor for myeloma, especially since my marrow was considered a good match.

NCI Study...: An nci study is looking at characterizing families that may be at higher risk to identify causes: screening individuals and families at high risk for hematologic cancers nct00052234 http://clinicaltrials.Gov/ct2/show/nct00052234?Term=nct00052234&rank=1. ...Read more

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How bad is multiple myeloma with 40% abnormal plasma cells in bone marrow?

How bad is multiple myeloma with 40% abnormal plasma cells in bone marrow?

Depends: The number of plasma cells is not the only determinant of prognosis. Are there bone lesions on x-ray? Is kidney function normal? Has there been a response to therapy? Many patients with 40% plasma cells at diagnosis can do well for years. ...Read more

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When a pet scan is done for multiple myeloma, is it to look at the solid lesions or a full body scan to look at bone marrow?

When a pet scan is done for multiple myeloma, is it to look at the solid lesions or a full body scan to look at bone marrow?

Both: A pet/ct scan looks at all parts of the body, from the skull top the feet, if appropriate. If there is abnormally increased (or decreased) glucose metabolism, it will be seen - in bone marrow or lymph nodes, lungs or solid organs. For multiple myeloma, since bone lesions are more likely, even more attention is paid to the bones and marrow. But, the rest of the body is also examined carefully. ...Read more

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Can there be different opinion on beta 2 microglobulin and bone marrow biopsy regarding detection on multiple myeloma?

Can there be different opinion on beta 2 
microglobulin and bone marrow biopsy regarding detection on multiple myeloma?

Beta 2 Microglobulin: Is a way of following myeloma response to therapy. The problem is that it can be elevated in other conditions- including benign ones. I've seen it very high in patients with kidney dysfunction. So the leel could be different than the bone marrow, which is the only real way to prove multiple myeloma. ...Read more

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Can multiple myeloma be seen on a CT scan? The tumor/lesion part, and/or the bone marrow involvement, or both or neither? Injected 350 contrast.

Can multiple myeloma be seen on a CT scan?  The tumor/lesion part, and/or the bone marrow involvement, or both or neither?  Injected 350 contrast.

Yes but not always: Xray, ct and MRI can be used to show bone destructions from multiple myeloma, but not always. Sometimes the disease is not severe enough & the bone destruction is not great enough to be perceptible. When enough disease is present, what can be seen is an area of loss of bone tissue, referred to as a lytic bone lesion. ...Read more

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Can you tell me if multiple myeloma is a brain/bone cancer or a brain/bone disease?

Can you tell me if multiple myeloma is a brain/bone cancer or a brain/bone disease?

Cancer: multiple myeloma is a malignacy of the plasma cells of the marrow. It presents with bone pain and lytic lesions usually diffusely invoving the spine. It is very effectivey treated with newer chemotherapeutic agents. p ...Read more

Dr. Liawaty Ho
734 doctors shared insights

Multiple Myeloma (Definition)

Multiple myeloma is a cancer of plasma cells (pcs). Pcs are the specialized b lymphocytes that produce antibodies. When there is a cancer or one (mono-) clone (= monoclonal, m) PC population they can product m-proteins. Symptoms include crab - hypercalcemia, renal (kidney) insufficiency, anemia, bone disease; also infection ...Read more


Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more