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Doctor insights on: Bone Marrow Biopsy Sedation

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What makes an a bone marrow biopsy abnormal?

What makes an a bone marrow biopsy abnormal?

Change in components: A bone marrow biopsy in a normal person will find the pattern of cells most often seen in a healthy person of that age. This would include red cells and their precursers (builders), white cells & precursers, platelet precursers & others. In illness, the pattern changes, and some or all may be abnormal. Tumor cells may take over every space& or few if any normal cells may be seen. ...Read more

Dr. Pen Hou
117 Doctors shared insights

Bone Marrow Biopsy (Definition)

A bone marrow biopsy is taken from the pelvic bone. A coring needle is advanced into the bone, which allows one to extract a sliver of the bone marrow, the red part of the bone. It is cut and viewed under a microscope. A bone marrow aspirate, obtained with a syringe, is usually bone at the same time. These are done to diagnose blood problems or to check for tumors in ...Read more


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Why could someone require a bone-marrow biopsy?

Why could someone require a bone-marrow biopsy?

Many Indications: Bone marrow biopsy is most useful in diagnosis and staging of blood cancers (leukemia, lymphoma, multiple myeloma, etc). Also indicated for evaluating unexplained anemia, leukopenia, thrombocytopenia, pancytopenia, or unexplained elevated blood counts. It is also useful for fever of unknown origin, or as a confirmation that bone marrow transplantation is successful. ...Read more

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What is the probablity of a clean bone marrow biopsy?

What is the probablity of a clean bone marrow biopsy?

Clarify your questio: In what setting? It depends on what disease, how long you have that, do you have systemic symptoms etc? For more indolent disease - like cll for instance- the chance to see involvement to the bone marrow is pretty high as the disease may have been there for years. For acute leukemia- definitely bone marrow will be abnormal. ...Read more

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Is there any disadvantage of having bone marrow biopsy?

Is there any disadvantage of having bone marrow biopsy?

Small risk: There is always risk involved in any procedure. Some have greater risk than others. Generally speaking, bone marrow biopsies are low risk, but your hematologist would be the best person to assess whether the risk outweighs the potential benefit, which is the real question. ...Read more

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I'm curious as to why would someone require a bone-marrow biopsy?

Long list: See this site for a list of indications for bone marrow biopsy.
http://www. Nlm. Nih. Gov/medlineplus/ency/article/003934.htm. ...Read more

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What are the chances of no complications from bone marrow biopsy?

What are the chances of no complications from bone marrow biopsy?

Low complication: The potential complications from bone marrow biopsy include bleeding and infection. A physician who does the procedure often will have, usually, a low complication rate. In general the rate should be very low (my guess is less than 1%). Remember, the procedure gives information not otherwise obtainable. Discuss with you physician and if you need it- go for it. ...Read more

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What should I expect in regards to pain during a bone marrow biopsy?

See below: Almost certainly they will deaden the area before doing the biopsy unfortunately they cannot deaden the bone so when they penetrate the bone for the biopsy there will be some immediate pain but it should be short and you ought to be able to stand it since you know it is going to happen. ...Read more

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Could you be sedated for a bone marrow biopsy?

Could you be sedated for a bone marrow biopsy?

Yes...: There is no reason not to be sedated and comfortable. ...Read more

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Will I need time off work after a bone marrow biopsy?

Will I need time off work after a bone marrow biopsy?

Not likely: The site of biopsy will be sore for a day or two, but you should be able to return to work the day after. More important for your ability to work may be the reason for which you need bone marrow biopsy. ...Read more

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What is the typical pain level of a bone marrow biopsy?

What is the typical pain level of a bone marrow biopsy?

Bone arrow biopsy: The bones are covered with a tissue called periosteum which has pain nerve fibres and is very sensitive to any injury. The doctor should numb the skin as well as this deeper layer. The needle is large but proper numbing would eliminate most of the pain. Once the numbing wears off, pain returns in a few hours but should be tolerable. Ice or tylenol (acetaminophen) will be helpful. ...Read more

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Should you drink the night before a bone marrow biopsy?

Yes.: Unless its being done under general anesthesia, you should eat and drink (including alcohol) as you would as part of your normal routine. If you are having a general anesthesia, you should take nothing by mouth for 8 hours prior to the procedure. If you are on blood thinners, check with your prescribing doctor to see if its okay to stop these to avoid excessive bleeding at the biopsy site. ...Read more

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Do you recommend eating/drinking before bone marrow biopsy?

Does not matter: If bone marrow biopsy is the only test you will have, eating food will not affect the results. However, your doctor may plan to do other blood tests as well, therefore it would be prudent to check with her/him. ...Read more

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How long does it take to get the bone marrow biopsy results?

How long does it take to get the bone marrow biopsy results?

Depends: It depends on the expected diagnosis. A metastatic tumor may be detected in three days or so. Workup of a hematologic disorder often requires multiple tests and may take a week or longer. ...Read more

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Is it possible to be completely sedated for a bone marrow biopsy?

Yes, if anesthesia: Is provided by qualified/ dedicated personell.
For many hospitals it means anesthesiologist and nurse anesthetists and it will depend on the scheduling, availability and logistics. For pediatric patients it should be the norm though ...Read more

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What is the purpose of collecting urine before a bone marrow biopsy?

What is the purpose of collecting urine before a bone marrow biopsy?

Ask your doc: Please ask your doctor this question. The number of conditions/diseases that can be tested for in the urine are quite numerous, ranging from everything from pregnancy to multiple myeloma proteins. ...Read more

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What are the differences between a bone marrow biopsy and aspiration?

Nothing...: They are literally one and the same... The aspiration is the procedure... And then the pathologist looks at the sample as a biopsy specimen. ...Read more

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What tests should be done frm bone marrow biopsy n aspiration slides?

Depends on purpose: How many tests can be done from blood? Millions. How many tests can be done from a bone marrow biopsy (BMB) specimen? Many? What tests should be done? It depends on 1) purpose for performing the BMB and 2) the findings the pathologist sees on morphologic examination of the aspirate & biopsy. Tests may include stains for iron or congo red (amyloidosis) as well as flow cytometry, cytogenetics, FISH. ...Read more

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How soon after a bone marrow biopsy could the diagnosis of leukemia be made?

How soon after a bone marrow biopsy could the diagnosis of leukemia be made?

Depends / 1 week: It depends. If the bone marrow is "packed" with cancer cells it may be obvious on an initial review by a hematologist and/or hematopathologist. However, for a new diagnosis I generally tell patients it may potentially be a week for special stains/studies and "send out" studies to fully characterize the bone marrow. ...Read more

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Is there another way to find out if you have leukemia other than a bone marrow biopsy?

Is there another way to find out if you have leukemia other than a bone marrow biopsy?

Yes: Often a bone marrow biopsy is needed to fully characterize a leukemia, but leukemia may be noted in the peripheral blood when it is smeared on a glass slide (pbs). Also, special tests on blood such as flow cytometry can (at least partially) characterize certain leukemias (eg, cll). ...Read more

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Can you tell me about a bone marrow biopsy from the chest and what is the experience like?

Outpatient procedure: A bone marrow biopsy, where a piece of bone marrow is removed cannot be done from the chest (sternum). It's too dangerous to do there. Instead, a bone marrow aspirate is done. The skin is cleaned, the area around the breast bone is anesthetized with local. A special needle is inserted into the bone. You will feel pressure from that. A syringe is used to draw blood. It might hurt briefly. ...Read more

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Can you tell me about having a bone marrow biopsy from the chest and what was your experience like?

When the bone: Marrow is sampled from the breast bone only an aspiration can be performed. The bone in this area is not thick enough to perform a biopsy ...Read more

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Is a bone biopsy painful? I'm nervous about my upcoming bone marrow biopsy. Is it painful? What sort of pain medication is used? .

Is a bone biopsy painful? I'm nervous about my upcoming bone marrow biopsy. Is it painful? What sort of pain medication is used? .

It: It depends where the biopsy is done and what type of anesthesia is used. Anesthesia may range from local anesthetic like lidocaine, conscious sedation or general anesthesia. Post operative pain maybe treated with narcotic pain medication. Good luck! ...Read more

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What to do if my bone marrow biopsy showed 25% increased ring sideroblasts. Is that a high amount and is that a bad sign that I'm in bone marrow failure?

More info: Why was the marrow done? Ringed sideroblasts are associated with myelodysplasia, a bone marrow disorder characterized by low blood counts, a serious blood disorder. See a hematologist for recommendations. ...Read more

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Is a bone marrow biopsy painful?

Yes and no: Any biopsy will be painful but in the hands of an experienced doctor and proper sedation (local novocaine) it can be a much more tolerable process. Pain killers such as tylenol (acetaminophen) afterwards for 24-58 hours can be a help too. ...Read more

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What amount is a bone marrow biopsy?

Bone marrow biopsy?: I am not clear what you are asking--do you want to know how much bone marrow is removed during a bone marrow biopsy?
Generally, 5-15 cc's of marrow is removed during a bone marrow aspiration and then a 2-3 cm small piece of the bone marrow is removed for the biopsy.

If you were trying to get other information please add a more detailed question. ...Read more

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Does a bone marrow biopsy cause pain?

Does a bone marrow biopsy cause pain?

Yes: A bone marrow biopsy unfortunately can be a painful procedure. It is only performed when the benefits outweigh the risks, however. ...Read more

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When do you need a bone marrow biopsy?

Blood disorders: A number of blood disorders like undiagnosed anemia, leukemia, high red cell count, low white cell or platelet count may warrant a bone marrow biopsy. See this site for more info.

http://www. Webmd. Com/cancer/bone-marrow-aspiration-and-biopsy ...Read more

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Can getting a bone marrow biopsy hurt?

It will hurt: Even with a local anesthetic and some sedation, you can expect a fair amount of pain. Be brave and remember that it's being done to promote your improved health. ...Read more

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What is a bone marrow biopsy done for?

What is a bone marrow biopsy done for?

Bone marrow biopsy: Hi, Bone Marrow biopsy is usually performed when a blood cell disorder is suspected, blood cell disorders are: Leukemia, aplastic anemia, multiple mylemoa and etc and some infectious processes. ...Read more

Dr. Daniel Saurborn
2 Doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more