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Bone Marrow Biopsy Chromosome Analysis
There is big differe: Bone marrow biopsy is done to obtain a pice of tissue to look under the microscope and find out if the blood formation is normal or abnormal. Chromosomes are not visible in the standard bone marrow biopsy. For this we need to culture the blood cells and capture the chromosomes when they are well formed just before the cells divide. This test takes a laboratory which can culture blood cells to see. ...Read more
A bone marrow biopsy is taken from the pelvic bone. A coring needle is advanced into the bone, which allows one to extract a sliver of the bone marrow, the red part of the bone. It is cut and viewed under a microscope. A bone marrow aspirate, obtained with a syringe, is usually bone at the same time. These are done to diagnose blood problems or to check for tumors in ...Read more
Yes: Usually, when a bone marrow biopsy/aspirate is done, additional material is collected for special testing, such as flow cytometry and chromosome analysis. While the most important information is obtained by microscopically examining the cells in the bone marrow, the results of those special studies can help the pathologist more specifically diagnose the cancer, if one is present. ...Read moreSee 1 more doctor answer
Bone marrow Biopsy showed 2 genetic abnormality. Another bone marrow done in same center showed no abnormalities. No treatment done. Any explanation?
Cytogenetic analysis: A bit more complicated. Not enough information to assess.Need more details on the exact type of genetic abnormality. Would be helpful to be able to view the entire genetic evaluation, complete blood count and history. Suggest that you seek a full one on one consultation. Good luck. ...Read more
Can be normal.: Up to 5% is normal as long as they are not "monoclonal" meaning derived from a cell. If monoclonal then a bone cancer called myeloma needs to be ruled out. If no bone disease, anemia, high calcium or kidney disease answer is MGUS, a pre-cancerous condition with low risk of progression (less than 1% per year). ...Read more
Not necessarily: Nephrogenic systemic fibrosis (nsf), also known as nephrogenic fibrosing dermopathy (nfd), is a disease of fibrosis of the skin and internal organs reminiscent but distinct from scleroderma or scleromyxedema. It is caused by gadolinium exposure used in imaging in patients who have renal insufficiency. ...Read moreSee 1 more doctor answer
Is bone marrow transplantation is curative for chronic myeloid leukemia caused by (Philadelphia chromosome) ?
Bone marrow biopsy?: I am not clear what you are asking--do you want to know how much bone marrow is removed during a bone marrow biopsy? Generally, 5-15 cc's of marrow is removed during a bone marrow aspiration and then a 2-3 cm small piece of the bone marrow is removed for the biopsy. If you were trying to get other information please add a more detailed question. ...Read more
Change in components: A bone marrow biopsy in a normal person will find the pattern of cells most often seen in a healthy person of that age.This would include red cells and their precursers (builders), white cells & precursers, platelet precursers & others. In illness, the pattern changes, and some or all may be abnormal. Tumor cells may take over every space& or few if any normal cells may be seen. ...Read more
Wat does cd 5;21;23 b cell lymphocyte present in bone marrow biopsy indicate.I have pancytopenia nd spleenohepatomegaly?
Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
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