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Doctor insights on: Body Rash With Taxol

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How does Taxol (paclitaxel) affect cells in the body?

How does Taxol (paclitaxel) affect cells in the body?

Stops cell division: Taxol (paclitaxel) is a chemotherapeutic agent that act to arrest rapidly dividing cells such as cancer cells. As such, it can also impede certain "normal" cell division such as white blood cels. Cell counts must be monitored frequently during treatment with this agent. ...Read more

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Dr. John Chiu
2,616 doctors shared insights

Skin Rash (Definition)

A skin rash is a symptom in which a person has changes on part or all of his skin, such as color changes, bumps, blisters, oozing, peeling, ...Read more


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What is the half life of taxol & carboplastin?

What is the half life of taxol & carboplastin?

Half lives: For Taxol, the half-life is dependent upon the length of the infusion. If it is a three hour infusion, the half-life is approximately 24 hours, but for a 24 hour infusion, it is about 52 hours. For carboplatin, the retention half life can be as much as 30 hours. Hope that helps. ...Read more

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What is Taxol (paclitaxel) typically used for?

What is Taxol (paclitaxel) typically used for?

Chemotherapy: Taxol (paclitaxel) is a very effective chemotherapeutic drug for the treatment of some forms of breast and ovarian cancer. ...Read more

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What exactly is the drug Taxol (paclitaxel) used for?

What exactly is the drug Taxol (paclitaxel) used for?

Chemotherapy: Taxol (paclitaxel) is a widely used chemotherapy drug for breast, lung, head/neck, esophageal cancers. ...Read more

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What are some contraindications of taxol (paclitaxel)?

What are some contraindications of taxol (paclitaxel)?

Not too many: Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil). Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read more

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Taxol (paclitaxel) side effects

Taxol (paclitaxel) side effects

Many: The most common side effects are hair loss, lowered blood counts, neuropathy, leg pain, mouth sores, and severe allergic reaction due to the solvent used to dilute Taxol (paclitaxel) (called cremophor). ...Read more

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Can Taxol (paclitaxel) treat pneumonitis?

Can Taxol (paclitaxel) treat pneumonitis?

No: Taxol (paclitaxel) is a chemotherapeutic agent used to treat malignant, metastatic disease. Pneumonitis is an inflammatory process that needs antibiotics to bring the disease under control. One of the complications of chemo like Taxol (paclitaxel) is suppressing the immune system. As such reports appear that pneumonitis following the use of Taxol (paclitaxel) as in breast cancer occurs following the use of this agent. ...Read more

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Is neulasta (pegfilgrastim) needed with weekly taxol?

Is neulasta (pegfilgrastim) needed with weekly taxol?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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What is the role of Taxol (paclitaxel) in chemotherapy?

What is the role of Taxol (paclitaxel) in chemotherapy?

Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more

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Dr. Cornelia Franz
1,059 doctors shared insights

Rash (Definition)

A rash is a change to skin condition which can affect color, appearance, or texture. It may or may not ...Read more