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Doctor insights on: Blood Test For Lupus Diagnosis

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Positive diagnosis (scleroderma, polymyositis) with negative blood tests? Is that common?

Positive diagnosis (scleroderma, polymyositis) with negative blood tests?  Is that common?

PM/Scl: The paradox of rheumatologic diseases is that there are more lab tests in this area than any other, and they of relatively less value compared to the history and physical findings than in other fields. If your rheumatologist is comfortable with the diagnosis of "scleromyositis", which usually features anti-pm/scl, i'd accept it even with a single negative result, and proceed. ...Read more

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What is considered a positive result for the SM antibody for SLE? My Ana 1:320 but DNA was negative. So many blood tests for SLE diagnosis!!

What is considered a positive result for the SM antibody for SLE? My Ana 1:320 but DNA was negative. So many blood tests for SLE diagnosis!!

SLE: hi, diagnosis of SLE is not base on blood test, positive DsDNA and ANA are just one out of 11 criteria for diagnosis of SLE, to diagnose SLE you need to have 4 out of 11 criteria. ANA is a non- specific test and false positive rate is high, especially in women and elderly. ...Read more

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What conditions will a CRP blood test detect?

What conditions will a CRP blood test detect?

None: C-reactive protein measures degree of inflammation in many diseases but does not actually detect any. ...Read more

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What is a positive SM antibody blood test for SLE?

What is a positive SM antibody blood test for SLE?

Marker for SLE: Systemic lupus erythematosus can exist without a positive test result but a positive result =SLE. This is not a happy Dx, but some people are well managed by good treatment and compliance w/ recommendations for how to live. A specialist Health Psychologist is often a great asset in learning how to deal w/ the condition and symptoms that can include and/or cause emotional problems. Best! ...Read more

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Is there a blood test for lupus?

Is there a blood test for lupus?

Yes: There is a simple blood test for lupus called an "ana" (for antinuclear antibody). It is positive, or detectable, in about 20% of healthy people, so it is only helpful as an initial screening. A doctor can ask questions, perform a physical exam and order further tests to figure out if a positive test indicates lupus. A negative test is very reassuring. ...Read more

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Would a Positive ANA Test CBC with a few other clinical criteria confirm DLE without need for Biopsy?

Would a Positive ANA Test CBC with a few other clinical criteria 
confirm DLE without need for Biopsy?

DLE Criteria: Studies show that up to 28 percent of people with DLE develop Systemic Lupus Erythematosus. If a person has SLE also the American College of Rheumatology and SLIIC criteria can be used to help determine the presence of disease. Studies have tried to validate the SLIIC criteria for DLE alone but DLE sometimes exists in a pathologically singular form. http://tinyurl.com/j6lvnv4 ...Read more

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I tested positive for lupus and negative for rheumatoid arthritis. How accurate are these tests?

I tested positive for lupus and negative for rheumatoid arthritis. How accurate are these tests?

Tests are accurate: If you have the right tests theses are quite accurate.You should discuss with your doctor who ordered the tests, because he knows your clinical history and will be able to explain the results to you.I can not answer without knowing the tests which were done. ...Read more

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Does the blood test for RA have false negatives?

Does the blood test for RA have false negatives?

Clarify: Done correctly, the test simply tells whether rheumatoid factor is present in the blood. Around 25% of people with obvious rheumatoid arthritis never develop rheumatoid factor in the blood. Rheumatology has many labs but all are ancillary to the history and physical exam. As a pathologits -- "treat the person, not the numbers.". ...Read more

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Will the regular blood test and western blot test for Lyme disease rule out someone having it?

Will the regular blood test and western blot test for Lyme disease rule out someone having it?

It is a good test..: Enzyme-linked immunassay is a sreening test which if positive will be confirmed with a western-blot (=standard of testing). Although not absolutely 100%, a negative western blot is a good bet that there is no lyme at the time of testing. Early disease/infection may have negative test, thus recommended retesting in about 3 wks. Lyme dna testing is better, but more expensive. Consult doc..Good luck. ...Read more

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Could you please tell me what blood test are used for lupus. I'm looking at blood test example CBC =blood count. Lupus= ?

Could you please tell me what blood test are used for lupus.  I'm looking at blood test  example CBC =blood count. Lupus= ?

Lupus blood tests: Have your physician order an ANA test. If that is positive, seek the care of a rheumatologist. For further tests. Patients with lupus are anemic, usually. ...Read more

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My doctor ordered a routine lab req for blood work. Can it detect Lyme disease?

My doctor ordered a routine lab req for blood work. Can it detect Lyme disease?

No: Routine blood work should not include testing for Lyme disease. The test is only to be run if there is suspicion that the individual has been infected and has the disease. Cholesterol and blood sugar are good screening tests. Tests for rheumatoid arthritis, lupus, Lyme disease are NOT screening tests as there are many false positives. ...Read more

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Blood tests positive but biopsy and urease test negative for h.pylori. Is this normal?

Blood tests positive but biopsy and urease test negative for h.pylori. Is this normal?

The blood test for: H. Pylori checks for antibodies against the bacterium. Antibodies are proteins that help your body fight off infection and they may be detectable indefinitely, even for a lifetime. Biopsy & urease tests check for presence of an active infection. (+) H. Pylori blood test with negative biopsy & urease suggests you had the infection in the past but that it's not currently active. ...Read more

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What tests check for blood clot disorders?

What tests check for blood clot disorders?

Blood clot: There are many blood tests to look for clotting disorders, both clotting too much and not quickly enough. If you are having active bleeding problems you should see your physician asap. If you are concerned about an inherited disorder blood tests can help here too. ...Read more

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Given a positive RNP antibody test, what are the clinical diagnostic criteria for MCTD?

Given a positive RNP antibody test, what are the clinical diagnostic criteria for MCTD?

MCTD: Usually considered diagnostic if high RNP titer, and two or more of the following: Raynauds, myositis, synovitis and swollen fingers/hands. ...Read more

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How precise is a blood test for celiac's disease?

How precise is a blood test for celiac's disease?

A panel of tests: There is a panel of tests and some tests when positive at high enough titer are diagnostic and other tests if negative rule out the diagnosis. The gold standard test is intestinal biopsy and evaluation by a pathologist. ...Read more

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Can a MCTD diagnosis always change? I tested positive for ANA and Rnp

Maybe: It will depend on how high the titers are and what signs / symptoms you have. Low titers may mean nothing at all. Without clinical evidence of multisystem disease, the diagnosis of MCTD is very, very unlikey ...Read more