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A type of MDS: Refractory anemia with excess blasts is a type of myelodysplastic syndrome (MDS). The bone marrow will have between 5-19% blasts per high powered microscope field. This illness is a "preleukemia" or an evolving leukemia. Progression to leukemia can happen in 12 months, and many patients will require transfusions for low blood counts. Treatments can prevent progression to leukemia. ...Read more
When the bone marrow biopsy shows that there is production of low number of RBC but normal and no blasts, is this MDS? What is unexplained anemia?
MDS Erythroid Progen: An MDS diagnosis requires ? 10% of bone marrow cells showing abnormal (dysplastic) maturation. (Attached image shows erythroid dyspl). The number of cells (red, white, megakaryocytes) can be high or low. Some clarification of RBC is needed. Low number of erythroid progenitors, as the only finding, can be due to many other issues: sampling artifact, parvovirus infection, pure red cell aplasia, etc. ...Read more
High platelet 499/450..Diagnosed wth microcytic anemia. Presence of few atypical lymphocytes in smear. No blast noted. Could ths be natural reaction?
My dad has low risk MDS. Only anemia, but transfusion dependent of theee units every 6 wks. Platelets and WBC are ok. Blasts in B.marrow1%. Prognosis?
Unpredictable: Don't try to second-guess. It's all percentage odds. He would do well to plan a normal life expectancy, but be prepared (as any person should be) for the onset of serious illness. ...Read more
Low blood count: Anemia is a low red blood cell count, it can caused by low iron levels or from loss of blood. Red blood cells carry oxygen through the body. If you are anemic you have less of this oxygen-carrying capability and symptoms include fatigue, racing heart and dizziness. It is usually treated with iron supplements. ...Read moreSee 2 more doctor answers
There are many ways: The therapeutic approach taken depends upon the underlying cause, and causes of anemia are many and varied. They can result from impaired rbc production (eg., nutritional deficiencies, marrow infiltration, etc), hematoma, blood loss (gi bleed, hemorrhage, epistaxis, etc.), hemolysis, thalassemia, hemoglobinopathies, etc. Do you have a specific cause that you would like information about re: rx? ...Read more
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