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Doctor insights on: Blastic Anemia

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What is refractory anemia with excess of blasts?

What is refractory anemia with excess of blasts?

A type of MDS: Refractory anemia with excess blasts is a type of myelodysplastic syndrome (MDS). The bone marrow will have between 5-19% blasts per high powered microscope field. This illness is a "preleukemia" or an evolving leukemia. Progression to leukemia can happen in 12 months, and many patients will require transfusions for low blood counts. Treatments can prevent progression to leukemia. ...Read more

Dr. Steven Ginsberg
1,239 doctors shared insights

Anemia (Definition)

Anemia refers to any condition where there is a decrease in the red blood cells in the body. There are numerous causes of anemia but they can basically be broken down into 3 categories: decreased production of red blood cells increased destruction of red ...Read more


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When the bone marrow biopsy shows that there is production of low number of RBC but normal and no blasts, is this MDS? What is unexplained anemia?

When the bone marrow biopsy shows that there is production of  low number of RBC but normal and no blasts, is this MDS? What is unexplained anemia?

MDS Erythroid Progen: An MDS diagnosis requires ? 10% of bone marrow cells showing abnormal (dysplastic) maturation. (Attached image shows erythroid dyspl). The number of cells (red, white, megakaryocytes) can be high or low. Some clarification of RBC is needed. Low number of erythroid progenitors, as the only finding, can be due to many other issues: sampling artifact, parvovirus infection, pure red cell aplasia, etc. ...Read more

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I was diagnosed with microcytic anemia due to heavy menstruation. Pbs shows few atypical lymphocytes. No blast seen. Could this be a reaction related?

Take iron: I wouldn't worry about the differential as long as u feel ok, unless one is wayyyy off, especially in the low direction. Take the iron and try the ocp for bleeding control. Look up lystedalysteda as well if u don't like hormones. ...Read more

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My dad has low risk MDS. Only anemia, but transfusion dependent of theee units every 6 wks. Platelets and WBC are ok. Blasts in B.marrow1%. Prognosis?

My dad has low risk MDS. Only anemia, but transfusion dependent of theee units every 6 wks. Platelets and WBC are ok. Blasts in B.marrow1%. Prognosis?

Unpredictable: Don't try to second-guess. It's all percentage odds. He would do well to plan a normal life expectancy, but be prepared (as any person should be) for the onset of serious illness. ...Read more

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What is anemia?

What is anemia?

Low blood count: Anemia is a low red blood cell count, it can caused by low iron levels or from loss of blood. Red blood cells carry oxygen through the body. If you are anemic you have less of this oxygen-carrying capability and symptoms include fatigue, racing heart and dizziness. It is usually treated with iron supplements. ...Read more

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What is anemia?

What is anemia?

Anemia: A low red blood cell count. Many potential causes that need investigation. ...Read more

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What ia anemia?

Low blood hemoglobin: Anemia is low blood hemoglobin (red blood cell part). It can be caused from many things, but particularly blood loss in menstruation from women and from cancer in the colon, or kidney disease. ...Read more

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What is anemia?

Low red blood cells: Anemia is a low number of red blood cells. The most common reason is low iron stores, but there are many other causes. In any case, if someone is anemic they need to find out why ...Read more

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Is anemia cureble?

Is anemia cureble?

There are many ways: The therapeutic approach taken depends upon the underlying cause, and causes of anemia are many and varied. They can result from impaired rbc production (eg., nutritional deficiencies, marrow infiltration, etc), hematoma, blood loss (gi bleed, hemorrhage, epistaxis, etc.), hemolysis, thalassemia, hemoglobinopathies, etc. Do you have a specific cause that you would like information about re: rx? ...Read more