Doctor insights on:
Birth Defects From Drug Abuse
No: The ova is already formed before any environmental influences. However, after conception, current drug use can affect the baby, but not previous activity. ...Read more
Is it possible that past hard drug abuse damage the ova (egg cells) in a woman and cause mental retardation or birth defects?
I have been trying: To find information on this, but the information seems to be focusing on maternal use during pregnancy and not before. It is also heavily focused on alcohol and cigarettes, with results showing that the children of women who smoke or drink have decreased attention spans. I believe, however, that your hypothesis is indeed possible. Perhaps one of my colleagues has found some research on this. ...Read more
Limb loss: Thalidomide was originally marketed in britain as a nausea drug during pregnancy. It later became evident that about 30% of women who used it during the 4-7 wk (when arms & legs were forming) gave birth to infants with defects. These ranged from absence of one or more limbs to malformation of the limbs that formed. ...Read more
Vague question, which particular drug? Lenght of use?
An occasional use may not be detrimental (this is no approval of use), ...Read more
Probably: While it is known that alcohol, tobacco, and many drugs used by a pregnant woman can have negative effects on her baby, the effects of paternal drug use are less clear. What is known is that many drugs reduce sperm production, or damage sperm, increasing the risk of infertility in men. Also, animal studies show that many drugs given to the father can result in birth defects in their offspring. ...Read more
How some drugs cause birth defect in pregnant womans? .Can it alter a baby's normal growth by producing some chemicals or change DNA & cause mutation?
All of the above: All of the things you mentioned can happen. In addition, some drugs can block certain steps in the formation of proteins needed to build the body, and then abnormal proteins form and defects occur. There are sooooo many different ways drugs and chemicals can affect the growing body - we probably don't even know al of them yet. ...Read more
Accutane: Because of teratogenic potential, this drug is therefore very tightly regulated. ...Read more
How does Accutane not affect your fertility after? It's so serious in causing birth defects while on the drug and messes up hormones, how is it safe?
Who says it's safe?: It is one of the more toxic drugs, and the only reason we use it is because for some people, the pain of living with severe acne makes its risks worthwhile. Accutane acts on rapidly growing tissues, which is why it is contraindicated in pregnancy; but it does not appear to be as toxic to ovaries and eggs as it is to an embryo or a fetus. ...Read more
Fertility doctor prescribed dexamethadone to prevent miscarriage. My wife has been on the drug for a week. We found research that concerned us concerning birth defects with the drug. Any thoughts?
Need more details: Don't know why your wife was given dexamethasone, but don't stop it suddenly without discussing w/your doctor. Don't believe all you read during your research without discussing that as well. ...Read more
Can a father's drug use during conception cause birth defects - for example cocaine, opioids, depressants, stimulants, LSD/Ecstacy?
Major drug abuse: A history of major drug abuse can cause damage to male reproductive health - but it would not be from a single use at the actual time of conception. I'd also think hard about the maturity and responsibility toward a potential child that you might expect from a man who abuses drugs enough to cause harm to his body. Creating a Life is serious business - even more than sex (which is too!) Be safe. ...Read more
Many reasons: First, are they really increasing, or are they just living. Up until recently in history most of those pregnancies with defects would miscarry or the baby die rapidly after birth. Now we save these pregnancies and children. However, if increase, it is likely the many environmental exposures we have in the industrial age, both in the air we breath and perhaps the foods we eat. ...Read more
Birth Defects: A physical or biochemical abnormality that is present at birth- it may be inherited or due to environmental influence. ...Read more
Time for consultatn: I would consult with your OB about available forms of testing. There are both screening and more specific tests for a variety of issues. High resolution ultrasound can detect many structural defects while blood tests or amniocentesis can detect others. There is no overall test that could guarantee a given baby does a problem that is missed by the usual screening. ...Read more
Stillbirth: Our biggest concern is that listeria infection in the expectant woman can cause death of her fetus. There have been cases traced to eating contaminated cheese and cold cuts. Please see my guide on what food to feed your family (and fetus); there are two answers and links to food safety there. ...Read more