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Doctor insights on: Biotinidase Deficiency Mut Analysis

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Hemoglobin 8.4, kft, anemia profile, protein electroph, iron, b12, folate, (folic acid) m protein - all normal. Kappa lambda ratio 2.96 - means ?

Hemoglobin 8.4, kft, anemia profile, protein electroph, iron, b12, folate, (folic acid) m protein - all normal. Kappa lambda ratio 2.96 - means ?

?Find cause for Anem: You have anemia for which your doctors should find a cause. This requires doing a variety of tests which a good physician or a hematologist(blood specialist) can do. Unless already done, you need an examination of your bone marrow and more tests till we find the cause of your anemia. The light chains may be hinting at a possible cause which can be checked further with a bone marrow examination. ...Read more

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Monoclonal T cell beta gene rearrangement in blood /normal CBC / ANA / CMP / high Uric acid. Bouts of itching and hives. Significance?

Monoclonal T cell beta gene rearrangement in blood /normal CBC / ANA / CMP / high Uric acid. Bouts of itching and hives. Significance?

?: Can still be chronic idiopathic urticaria, but other lab tests need to be performed as well: thyroid function tests, thyroid antibodies, complement levels, stools analysis, etc.. also other pieces of history need to be known, better see an allergist, check aaaai.org or acaai.org for an allergist in your area, meanwhile keep taking whatever antihistaminic on regulat basis, good luck ...Read more

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Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Not likely: Please consult this site for info in this topic. Folate (folic acid) and B12 are needed for efficient red cell production and other functions, but lack of one does not increase the other. http://www.webmd.com/diet/folic-acid. ...Read more

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Cholesterol HDL 0.64 LDL 1.8mmol/L,clinically significant? unexplained symptoms see hX. Folate (folic acid) & vit d deficient, IBS-like sympt. And LFTs deranged.

Cholesterol HDL 0.64 LDL 1.8mmol/L,clinically significant?
unexplained symptoms see hX. Folate (folic acid) & vit d deficient, IBS-like sympt. And LFTs deranged.

Cholesterol panel: Hi, you Cholesterol panel is normal, but someone needs to figure out why your liver function is abnormal and also your spleen is enlarged, please see a liver specialist for further work up, it seems you only had Hep C test, how about Hep B and A and HIV, also autoimmune w/u like ANA, ANCA, Anit-KL ab, anti-mitrochondral Ab and etc. ...Read more

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Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?

Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?

Anemia: can be caused by blood loss or bone marrow suppression as well. More information is needed ( how long have you had a normal iron, folate (folic acid) and b12 level. What is your reticulocyte count ? ( is your bone marrow producing new RBC's) ? How low is your HCT and has it come up or gone down with B12. Is the RDW elevated ( do you put out large and small RBC's at the same time? Any blood loss ? ...Read more

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Is omega 3 deficiency and vitamin a deficiency genetic?

Is omega 3 deficiency and vitamin a deficiency genetic?

Vitamin deficiency: Not usually. Vitamin deficiencies are usually due to dietary deficiencies, but rarely can be related to problems absorbing nutrients. That may be due to a genetic defect. ...Read more

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Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more

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Does deficiency of vitamin e, zinc, selenium, l-carnitine cause low sperm motality?

Does deficiency of vitamin e, zinc, selenium, l-carnitine cause low sperm motality?

Low zinc, sel, carn.: There is evidence that zinc, selenium ; l-carnitine can improve sperm motility. Vit e deficiency may cause infertility but does not seem to affect motility. See http://www.Truestarhealth.Com/notes/1040005.Html ; http://www.Webmd.Com/infertility-and-reproduction/news/20050309/sperm-swim-better-with-carnitine ; http://www.Alive.Com/articles/view/17772/6_ways_to_boost_male_fertility_naturally. ...Read more

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What type of doctor tests for cerebral folate (folic acid) deficiency?

What type of  doctor tests for cerebral folate (folic acid) deficiency?

Tough: I'm not sure that testing cerebral folate (folic acid) is different from blood folate (folic acid). If you are wondering about depression and folate (folic acid) and being low in the ability to convert folate (folic acid) to l- methylfolate (folic acid), it is a trial of medication, generally. I could be wrong but a neurologist is the brain doctor. I'm not sure u need that though. ...Read more

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Person w/ SCAD deficiency, autism, mood disorder. Acutely became agitated, aggressive. Labs/UA wnl except B12 >1999 pg/mL; Folate (folic acid) >19 .9 ng/mL? toxic?

Person w/ SCAD deficiency, autism, mood disorder. Acutely became agitated, aggressive. Labs/UA wnl except B12 >1999 pg/mL; Folate (folic acid) >19 .9 ng/mL? toxic?

How old are you?: We need to know your age. Please put it in your public profile. We cannot answer questions from minors. Knowing your country or state helps, too. Age, location, and gender, can affect our answer, since some conditions are more likely in different places or in different age groups. Be honest! You expect if of us, & we expect it of you! List any meds you take, & any chronic medical problems, too. ...Read more

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What would cause folate (folic acid) deficiency in an 18 y/o male?

What would cause folate (folic acid) deficiency in an 18 y/o male?

Inadequate diet: This is caused by not eating enough foods rich in folate: dark leafy greens (spinach), beans & lentils, cruciferous vegetables like broccoli.You can also obtain folate from supplements, though most supps have folic acid, a synthetic form you need to convert to folate. 1/3 of people can't make that conversion & thus should take l-5-mthf. See http://www.Whfoods.Com/genpage.Php?Tname=nutrient&dbid=63. ...Read more

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What does low white cell count, positive p anca, upset stomach , gallstones, deficiency of D vitamin mean ?

What does low white cell count, positive p anca, upset stomach , gallstones, deficiency of D vitamin mean ?

Gallbladder disease: Gallbladder disease, stones or passing a gallstone can feel like stabbing pain into your back. The severity can be so intense, like a heart attack. Fatty foods make it worse. Your doc will get blood labs and ultrasound to make diagnosis. You may have 2nd diagnosis. Risk/benefit analysis is usually in favor of laprascopic cholecystectomy aka gallbladder removal. Be well. ...Read more

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What is hemagglutinin (ha) gene and neuraminidase (na) gene?

What is hemagglutinin (ha) gene and neuraminidase (na) gene?

Flu virus genes: The hemaglutinin and neuraminidase genes are in influenza viruses. They code for proteins that are found on the surface of the flu virus. The viruses are named according to which type of hemaglutinin and neuraminidase proteins are on their surfaces (for example: h1n1 or h7n9). ...Read more

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Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Increased aldolase,  complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more

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Found out unknown cause folate deficiency-rX 5mg folic acid tabs,how long before replenished? When to retest? Causes ?VIT D borderline deficient too

Folate (folic acid) deficiency : Folate (folic acid) deficiency can be caused by nutritional deficiency, medications, chronic diseases or frequent use of tanning beds. 5mg of folate (folic acid) is often used to treat deficiency. Usually 4 months of treatment is needed, then dose can be reduced. Levels may be rechecked after 2 a 4 months. ...Read more

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Which viruses and/or bacteria, if any, are known to affect and/or mutate the vdr gene ( vitamin d receptor gene)?

Which viruses and/or bacteria, if any, are known to affect and/or mutate the vdr gene ( vitamin d receptor gene)?

Deficiencies in gene: Due 2 infection are unlikely the cause of poor vit d function, it's usually vit d deficiency, lack of sunlight. Not sure, it's low probability. Other symptoms may get relief if u sleep better at night w/better daytime energy. It's not hard with the proper meds. I bet your memory due 2 anxiety/ mood issue. The meds can b tailored to help pain, must sleep for pain control. Private for med review? ...Read more

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What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?

What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?

Reason for doing it: What was the reason you got this done. In all patients we don't do T cell count, Immunoglobulin level estimation etc. What were your symptoms. Based on your answerc an give a better explanation. In any patient we do CBC- complete blood count with differential count.Only in people with suspected immunodeficiencies/hematological problems-dyscrasias is the term we use, detailed Tcell,B cell ,Ig done ...Read more

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With bipolar ii, adhd, & c ptsd, what additional tests are beneficial? Ie: hormone, neurotransmitter , DNA mutation (mthfr, a1at ...) methylation etc.

Yes: I would definitely check mthfr and comt. Both these are involved in methylation. One is involved in neurotransmitter synthesis, and the other in breakdown. Therefore polymorphisms can impact mood, etc, and if so, vitamins and supplements can help the methylation cycle. I check mthfr in most of my patients. ...Read more

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Will a folate (folic acid) deficiency lead to a vitamin B12 deficiency?

No: Many people on self-imposed restrictive vegetarian diets get both. They have similar effects on the blood and are both very serious health problems. ...Read more