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Doctor insights on: Bilirubin Slightly Elevated

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Sometimes my indirect bilirubin is slightly elevated and sometimes it's normal. Dr said it was gilbert's... Does this sound right?

Sometimes my indirect bilirubin is slightly elevated and sometimes it's normal. Dr said it was gilbert's... Does this sound right?

Yes: Gilbert's folks tend to have the bilirubin go up when they've missed a few solid meals. It's extremely common. If you feel well and this is your usual state of health, ignore it and be grateful. ...Read more

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Dr. Aaron Milstone
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Bilirubin (Definition)

Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more


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Liver ast/alt test was elevated, now they are normal; liver us was normal. Bilirubin is slightly elevated and i'm going for a GI consult. Causes?

Liver ast/alt test was elevated, now they are normal; liver us was normal. Bilirubin is slightly elevated and i'm going for a GI consult. Causes?

Many possibilities: You may already know the answer by now, if you have seen the GI specialist. Elevated bilirubin may be side effect of drugs, excessive destruction of red cells, blockage to the flow of bile and more. ...Read more

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Dr. Aaron Milstone
Board Certified
21 years in practice
1M people helped
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My bilirubin is sometimes slightly elevated. It's usually just indirect but there have been a few times when direct was 0.3 instead of under 0.2. U/s normal, blood work normal.goes to normal after eating. Gilbert's? Been 3 years since last test. Feel fine

Direct bilirubin: Gilbert's syndrome is a the most common hereditary cause of increased bilirubin. It is a genetic condition found in up to 5% of the population. Gilbert's syndrome rarely causes symptoms. However, in Gilbert's, it is the direct (unconjugated) bilirubin which is elevated. ...Read more

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Dr. Aaron Milstone
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21 years in practice
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I have slightly elevated bilirubin, my urine showed trace amounts of blood, and I have muehrcke's nails. How worried should I be?

I have slightly elevated bilirubin, my urine showed trace amounts of blood, and I have muehrcke's nails.  How worried should I be?

Elevated bilirubin: You may have g ilbert syndrome which can cause hypoalbuminemia which in turn can cause softening of your nails and muehrcke's nails. ...Read more

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I have slightly elevated bilirubin, my urine showed trace amounts of blood, and I have muehrcke's nails. How worried should I be?

Concerning: Muehrcke's lines of the nails are indicative of decrease protein synthesis. It is alo called leukonychia striata. With concomitant elevated bilirubin and hemturia, this can indicate conditions relating to liver or biliary conditions, metabolic stress, nephrotic condition, other systemic disease or malnutrition. ...Read more

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My bloodwork shows slightly elevated bilirubin but normal AST and alt. What does this mean and should I worry?

Gilbert's syndrome: This is a benign condition that requires no treatment characterized by mildly elevated bilirubin and otherwise normal liver function tests. The bilirubin can be higher with fasting which is why we often see it on routine blood work. It is not a disease and again requires no treatment. ...Read more

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I have elevated CRP and C4 levels. C3 is normal. Last two blood work-ups also revealed slightly elevated bilirubin levels. What could this indicate?

Non-specific: Interpreting blood work can be a very tricky proposition. Each lab values needs to be interpreted within clinical context and in association with other blood tests. Elevated CRP can sometimes be normal, other times it is a marker of inflammation. Elevated bilirubin may also be normal but sometimes can be indicative of blood or gallbladder dysfunction. ...Read more

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Slightly elevated bilirubin (1.7) with elevated WBC (12.6) and RBC (5.35). History of ERCP and Gall bladder removal. Is this cause for concern?

Fevers?: Are you having fevers or chills? Do you know what your bilirubin was before? These labs warrant further investigation especially if you have any symptoms. ...Read more

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Dr. Aaron Milstone
Board Certified, Pulmonology
21 years in practice
1M people helped
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