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Three mechanisms: High bilirubin that is almost all unconjugated means hemolysis (tearing up red cells too fast) or gilbert's non-disease. If it is mostly conjugated, the bile ducts are obstructed, perhaps by a stone or tumor. If both are way up, probably the liver cells are being damaged. ...Read moreSee 1 more doctor answer
Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more
Can high level of bilirubin like 8 damage organ if it os present for a long time. Time like 2 months ?
Newborns: Light therapy is used for newborns who have high bilirubin. Light converts insoluble bilirubin to soluble form that can be excreted in the urine. In the newborn it is a temporary issue. The same does not apply to adults. See this for more info. https://www.nlm.nih.gov/medlineplus/ency/article/002394.htm ...Read moreSee 1 more doctor answer
Never a problem: Labs "normal ranges" are set up so that a few percent of people fall below and above the reference range. As a pathologist who's devoted a lifetime to the lab, i can't emphasize too often that patients and doctors must both "look at the person, not the numbers.". ...Read moreSee 1 more doctor answer
How to reduce bilirubin level? Home remedies or natural ways preferred. I have cliger najjar syndrome. Thanks
Not much available: You showed courage by asking. "home" and "natural / vitamin / holistic / supplemental" remedies won't touch it. I'm going to assume you have type ii. You may have some success with Phenobarbital but it will make you tired most of the time and much less effective -- much worse than being a little bit yellow. Reassure folks it's not contagious. Focus on what you can do well. Best wishes. ...Read moreSee 1 more doctor answer
0 to 1 by our lab: Depends slightly on lab used. Our lab uses 0.0 to 1.0 fmg/dl or total bilirubin and 0.0 to 0.3 for direct bilirubin. Direct/conjugated bilirubin can be elevated in liver/biliary system disease, and indirect/unconjugated bilirubin can go high with hemolysis (break-up of red blood cells in blood stream), can be a harmless inherited condition (eg gilbert's), and has various other causes. ...Read more
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