Doctor insights on:
Bilirubin Direct And Indirect
Bilirubin direct and indirect fluctuate (indirect 1.2, direct 0.1, total 1.3...Another test: indirect 0.43, direct 0.54, total 0.97), lfts normal.
Might be Gilbert's: A relatively large portion of the population has something called gilbert's, which is completely harmless, and causes elevated indirect bilirubin in times of stress or illness. If you are completely healthy and just have an elevated indirect bilirubin from time to time, it is almost certainly gilbert's. Ask your doctor what he/she thinks. ...Read more
Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more
Can gilbert's also present with mildly elevated direct bilirubin (0.4-0.7)..with elevated total (1.4-2.2) Mostly indirect still some direct elevation?
Not from Gilbert's: Gilbert's syndrome causes a deficiency in the enzyme that converts indirect bilirubin to direct bilirubin. In other words, the only issue is that indirect bilirubin is converted to direct bilirubin more slowly. People with Gilbert's are not unhealthy from it and are not considered to have a "disease." If direct bilirubin is elevated, something else is going on. ...Read more
RBC antibodies: These tests are used to detect antibodies against red blood cells (rbcs). The direct coombs test is used in autoimmune hemolytic anemia. That's when your antibodies attack & destroy you own rbcs. The indirect test is used to detect potential transfusion reactions & in pregnancy especially for rh incompatibility when mom is rh- & fetus is rh+. For a more complete explanation see wikipedia. ...Read more
Total bilirubin 2.5 (Elevated), Direct bilirubin 0.5 (Elevated), Indirect bilirubin 2.0 (Elevated) All other liver enzymes normal. What causes this?
Rerun test: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you need to re do the tests in non-fasting state. With the exception of elevated direct bilirubin, the findings are consistent with Gilbert syndrome, which is not a disease. See this site for more info: http://www.mayoclinic.org/diseases-conditions/gilberts-syndrome/basics/definition/con-20024904 ...Read more
Chronic Elevated Total bilirubin (2.5) direct bilirubin (0.5) and indirect bilirubin (2.0). All other liver enzymes are normal. What causes this??
Sounds serious: Hello again Matt. If your direct bilirubin is actually 0.5 mg/dL now, then this is more than Gilbert's which I understand is diagnosed. If this is not a lab error, then I suspect you have cholestasis too for some reason and you deserve a workup by somebody who's good with liver disease. Actually, the alprazolam / Xanax you're taking occasionally causes this. You might start there. Best wishes. ...Read more
Recent blood test shows high direct bilirubin.Total bilirubin is 0.7 &direct0.5 and indirect 0.2. ALT,AST,GGT,Alk.Phos are in normal range.Is it ok?
Okay: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is nothing in your results to be concerned about. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
Indirect bilirubin 1.6, direct 0.3. Direct is only 0.1 above normal. Dr. Said gilbert's. Abdominal u/s normal. Gilberts?
Sgpt 950 alkaline phosphatase 298 total bilirubin 5.5 direct bilirubin 4.4 kindly answer cause obstructive jaundice or hepatitis?
Yes: The direct coombs test is typically used to test for autoimmune hemolytic anemia, a disorder involving destruction of red blood cells. It determines whether or not antibodies are present on the surface of the patient's rbcs. The indirect coombs test is typically used to test for blood type compatibility prior to a transfusion, and detects the presence of antibodies in the serum of the patient. ...Read more
Hi my liver test total bilrubin 1.7 direct bilirubin 0.6 and indirect bilirubin 1.1 all other are normal can I take acholal or not?
Don't Rx labs: You indicate that you have a history of known liver disease. You need to learn the cause. With mixed direct and indirect being high, this is almost certainly intrinsic liver disease and this is serious. But you ask only, "can i drink alcohol?" if alcohol is the cause of your liver disease, this is a suicide course. If not, you need to find what's wrong with your liver ; seek rx, alcohol-free. ...Read more
See below: Increased indirect bilirubin caused by overproduction of bilirubin ( breakdown product of red blood cells), reduced bilirubin uptake, or impaired bilirubin conjugation. Many causes, but in absence of other symptoms and a history of elevated bili in past this is likely a benign genetic disorder. However, there are other potential causes and you should see your doc to make sure. ...Read more
Out of context: Thank you for letting us know. But those tests are not interpreted alone without context or medical history. ...Read more
My total bilurubin 0.88 direct bilurubin 0.37 indirect bilurubin is 0.51, serum globulin is 3.27 Are these levels normal?
See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your globulin level is higher than normal. It can be due to many causes, e.g., chronic infection, inflammatory disorders, liver disease and myeloma. Please discuss the matter with your doctor. ...Read more
ItCanBeINDIRECTLY:-): Jaundice is the medical term for an elevated bilirubin level in the bloodstream; this is a breakdown product of red blood cells, normally excreted via the liver into the digestive tract. Total bilirubin levels consist of direct+indirect. Elevated direct bili can occur from any liver disease or obstruction of the outflow of bile from the liver, which can occur when a stone blocks the bile duct. ...Read more
For two years indirect bilirubin has ranged from (.9-1.7) direct from (.1-.4). Dr said gilbert's. Normal liver enzymes and u/s. Gilbert's?
Probably: Especially if you can relate the higher levels to times when you may not have been eating so much. I trust there's no evidence that anything else is wrong. ...Read more
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