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Four months ago total and direct bilirubin was elevated. Now normal. Fibroscan ultrasound and CT found nothing wrong with liver. What was it???
Not sure.: And unless it recurs, you'll probably never figure it out. Sometimes that pattern of abnormal liver tests can occur when someone passes a gallstone. There could be many reasons other than that, however, and no further testing is necessary as long as the labs have returned to normal. Good luck. ...Read more
Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more
Don't Rx lab value: Try to get into one of the studies of the new protocols that are likely to be curative. If this happens, your cirrhosis is likely to regress. Your physician can guide you. ...Read more
See below: Increased indirect bilirubin caused by overproduction of bilirubin (breakdown product of red blood cells), reduced bilirubin uptake, or impaired bilirubin conjugation. Many causes, but in absence of other symptoms and a history of elevated bili in past this is likely a benign genetic disorder. However, there are other potential causes and you should see your doc to make sure. ...Read more
Total bilirubin- 4.5 direct bilirubin- 0.3. Is this ok? Liver functioning all normal other than that
Gilbert's syndrome: Yes. This is very consistent with gilbert's. In the us, approximately 3-7% of the population has gilbert's. Typically patients with gilbert's will have a total bilirubin <6 (like you). It can fluctuate and worsen during times of illness, stress or dehydration. It will not negatively affect your health. ...Read more
Cmp completely normal but total bilirubin 4.0 and direct bili- 0.9. It's always high and seems to be creeping up. Is this ok? I have no gall stones.
Gilbert's syndrome: You likely have gilbert's syndrome, which is the most common hereditary cause of increased unconjugated (indirect) bilirubin due to reduced activity of the enzyme glucuronyltransferase. It is found in 5-10% of people and normally has no serious consequences. Mild jaundice may appear under conditions of exertion, stress, fasting, and infections, but the condition is usually asymptomatic. ...Read more
I went for a AST test and was 201.60 and ALT was 126.60 GGT was 483.60 serum direct bilirubin 4.70 please help?
Need more info: Elevations in these markers can mean many things. But it points to your liver or an obstruction of your bile pathways. The causes could range from hepatitis, alcohol, cirrhosis, gallstones, or other things. You should discuss this with your doctor. Other tests like alkaline phosphatase and ultrasounds would be helpful. Also a history of pain, infection, how long have these tests been be helpful. ...Read more
How can I tell if my gallbladder has gangrene? Only functioning 15%. I'm constipated, have jaundice, low grade fevers. Ttl bilirubin- 4.5.
You need medical att: Do not put off going to md. ...Read more
N ER last night for jaundice! Liver came back perfectly normal. No elevations but total bilirubin-4.5. Found out gallbladder is only functioning 15%?
Need more info: There are lots of things that can produce bili 4.5. Need to know if this was direct or indirect and the other results of studies. I suspect you had a ct. I wonder if the gb issue is peripheral. ...Read more
Ttl. Bilirubin 4.5. Direct 0.9 and yellowing of eyes! Liver functioning normal. Neg for hepatitis. Gallbladder ultrasound norm. Gilbert's disease?
Your description is classic for diagnosing gilbert's. Given how many repeated questions you have written questioning this diagnosis, you could spend $400 to get the gene responsible for gilbert's sequenced to verify the diagnosis. See:
http://dnatesting. Uchicago. Edu/tests/65. ...Read more
Sgpt 950 alkaline phosphatase 298 total bilirubin 5.5 direct bilirubin 4.4 kindly answer cause obstructive jaundice or hepatitis?
Liver functions: Both are possible. Need to also exclude alcohol abuse. If you do not drink excessive alcohol the check with your physician (for liver scan, CT etc.) ...Read more
Cirohsis, bilirubin 4.2, heart EF 20-25%, brain stroke, left side weak, BP is very low, stable with saline sol. Pulse fluctuating. Pl advice?
Severe illness: This is multiorgan failure, and the outlook is not great, but the only way to assess this is to be the doctor in charge of managing the patient. In addition to determining the therapy there should be discussions on end of life decision making. Hope this was helpful. ...Read more
Hscrp 9.56 mg/l, ESR 36, eosinophils 0.46, total chlstrol 218, LDL 146, ratio 4.64 bilirubin 4, sgpt 127, sgot 79 gamma 33, vit d 6.8. Fatty liver?
Depends: Your liver studies are elevated, indicating there may be something going on with the liver. Your lipids are also high and this can predispose to fatty liver. However, other factors like viral hepatitis, alcohol, or certain medications can also raise the liver markers. You should follow up with your doctor or a specialist since imaging studies and/or liver biopsy may be necessary for diagnosis, . ...Read more
Age 36, no alcohol. Bilirubin 4 sgpt 127 sgot 79 liver size 14.5cm. Diffuse fatty liver. No biliary dilatation. Common duct 2mm. Confirm fatty liver?
Can gilbert's also present with mildly elevated direct bilirubin (0.4-0.7). with elevated total (1.4-2.2) Mostly indirect still some direct elevation?
Not from Gilbert's: Gilbert's syndrome causes a deficiency in the enzyme that converts indirect bilirubin to direct bilirubin. In other words, the only issue is that indirect bilirubin is converted to direct bilirubin more slowly. People with Gilbert's are not unhealthy from it and are not considered to have a "disease." If direct bilirubin is elevated, something else is going on. ...Read more
My bilirubin 1.4 I don't drink. What can cause it? Is it considered concerning? The rest of blood is Normal, I retake the blood on couple of weeks.
Gilbert's?: If this is mostly indirect / unconjugated bilirubin, you may be one of the 1-2% of folks with Gilbert's non-disease. It's not worth a workup though it can be done. If you've noticed in the past that the whites of your eyes turn slightly yellow if you go a few days without eating, consider the diagnosis clinched. Your physician should be familiar with this. Best wishes. ...Read more
Likely unrelated: Based on the limited information, unlikely related. If vitamin d level is severely low and one has gilbert syndrome, it can stress the body and bilirubin can be high. Would need to know if this is direct or indirect bilirubin (not just total). Needs further evaluation and follow-up at 4.5. ...Read more
My total bilirubin is 36.7Umol/L, directive bilirubin is 4.4umol/L. I also did liver testing which shows I have no hepatitis B. Give me some adivce.
See a specialist: You should see a hepatologist and gastroenterologist for to coordinate and plan your ongoing care. ...Read more
A 15 year old boy's total bilirubin is 0.8 and direct bilirubin 0.4. The total bilirubin is in range but direct bilirubin is slightly out of our lab range [0-0.3]. What might be the possible causes?
Meaningless: Difference. No clinical correlation.Get a more detailed answer ›
Hepatitis: This elevated enzyme is consistent with hepatitis. Has your physician checked for hepatitis A, B, or C or mononucleosis? A liver and gallbladder ultrasound are other tests that could be done. I'm not familiar with the medications you listed. A gastroenterologist is best qualified to evaluate and advise you. I assume alcohol or other toxins are not a factor. ...Read more
My wife is 29 week pregnant and she get jaundiced (Bilirubin-0.4 mg/dl) and eatching also. Can it effect my unborn baby? What precautions to be taken?
Any symptoms?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, do you have any symptoms? Why was the test done? Both values are higher than normal, but it would require more information for a meaningful answer. ...Read more
Hx of rectal ca sp LAR, CEA 4m interval rise from <0.5 to 2.4, Bilirubin 0.4, alkaline phosphatase 46, ALT 46, but high AST 79. What's the cause?
Viral jaundice, now normal bilirubin from 4 mnths n norml lft frm 2 mnths had alcohol n slight pain in right abdomen, how much time shud I avoid it?
Viral jaundice normal bilirubin from 4 mnths normal lft 2 mnths, had alcohol nd slight pain in right abdomen shud I continue daily use of alcohol?
NO!: You had a significant injury / insult to your liver and want the "ok" to continue daily assault on it with alcohol? No. Particuarly when having pain? No. Daily alcohol by most persons exceeds the "one-a-day" that might be healthy, so no. Let your liver heal--takes about 2x as long as time ill (so about 8 months), then small quantiy, infrequent alcohol may be ok. ...Read more