Doctor insights on:
Bilateral Breast Cancer Prognosis
Yes: Breast cancer can be stage 0 non-invasive. Stage1, stage 2, stage 3 and stage 4. Each of the stages has a variety if statistical possible outcomes and results. Also depends on cell type, hormone receptors, dna of the tumor, response to treatments and radiation, underlying health factors, etc. Too complicated to discuss here. The oncologist can be more specific for the patient's specific situation. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Need more info...: All else being equal, women with triple negative breast cancer have a worse prognosis than those who are receptor-positive; however, prognosis is highly correlated with the size of the cancer and the presence of cancer within the axillary lymph nodes. Furthermore, some women are more responsive to chemo than others, which will affect prognosis. ...Read more
Curable!: Stage 3 means the tumor is large and/or the cancer has spread to many lymph nodes. It can still be cured with a combination of surgery, chemotherapy and radiation therapy. The risk of cancer returning depends on many factors-- age, # of involved lymph nodes, and whether the cancer has hormone receptors or her2. About 50% of stage 3 breast cancer patients are cured. Have hope! ...Read more
Both: These tumors are on average more aggressive than their HER-negative counterparts, but also respond to herceptin (trastuzumab) which is very effective. ...Read more
Which is easier to cure a breast cancer who is a pr/er positive and her2 negative or er/pr negative and her2 positive? Who has longer prognosis?
In general, er+ has better prognostic features. However, the entire picture has to be evaluated (tumor size, lymph node involvement, distant spread) in order to determine prognosis for you.
A big factor is individual biology. Tumors are different in different people, different ages and even ethnicities. Focus on following your prescribed treatment regimen and thinking positive. ...Read more
Depends: Lymph nodes are one aspect of evaluation for stage and treatment of breast cancer. It depends on size of breast cancer itself, number of lymph nodes involved, hormone status of the tumor, and dna testing can also help identify breast cancer risks. If the lymph node involvement is small, then there is little additioanl risk to the patient. There are many factors involved in assessing breast cancer. ...Read more
It is not very usual: To have two cancers at once' more likly the breast cancer is the cause of the liver lesion (s). Ifthere is doubt, a biopsy can be done to verify cell type and establish appropriate treatment, including presence of er/pr/her-2-neu - cell surface marker suggesting treatment. Liver metastasis can respond, but classically less responsive to hormones, and not having as favorable outcome to therapy. ...Read more
Very good: I am sorry to hear about your diagnosis. The most recent us data reports a 5-yr survival rate of 81% for stage iia and 74% for stage iib breast ca. However, keep in mind these #s do not take into account the age and/or health of the patient, the specific tumor markers, nor the most current rx options. I am certain that your oncologist can give you much more information about your specific cancer. ...Read more
Receptors: This really depends on whether the tumor displays the estrogen, progesterone, and her-2 receptors. You can find this on your pathology report or you can ask your oncologist. The positive nodes is a worse prognosis than if 0 nodes were involved, but the prognosis can still be decent based on the receptor status that I mentioned. ...Read more
Someone I know had breast cancer about 3 years ago. Within the past year, the cancer spread to the spine and liver. What is the prognosis?
Varies: This depends on her response to treatment and her overall health. The average 5 year overall survival for someone with stage IV breast cancer is 15%. ...Read more
What happens if my friend has breast cancer and results of a biopsy of her thyroid shows cancer, what's her prognosis?
Probably separate: Hi. The breast cancer and thyroid cancer are probably unrelated. I've never seen breast cancer metastasize to thyroid. Thyroid cancer generally has a high cure rate. It's not fair she's had these cancers but life isn't fair. I bet the thyroid cancer with treatment will go well. I hope the breast cancer is in remission. She might outlive us all! :-) ...Read more
What is the prognosis, if my wife had breast cancer and it has now mets to the brain and she has 8 modules and several lesions?
Breast cancer patients with brain metastases have a strong tendency to do better than the average patient with brain metastases.
So you should treat it aggressively, but delicately, with fractionated whole brain radiation (i would give 40 gy/20 treatments for metastases from breast cancer) and salvage radiosurgery or surgery to any lesions that grow. ...Read more
This depends: The answer depends on many factors. How old is the persone, what other medical problems do they have, when did the breast cancer first occur, what other sites are involved, what are the characteristics of the cancer (estrogen, Progesterone receptors, her2/neu status) and what prior treatments were administered are some of the issues that factor into an answer. ...Read more
Treatable, NotCurable: The term "prognosis" is like an on/off switch and does not take into account disease control and quality of life. After all, diabetes is incurable but doesn't have the same connotation as cancer. Many breast ca patients with bony mets respond very well to rx and can live for years with this. It is best to focus on response to rx rather than cure. ...Read more
Can you tell me if my friend has breast cancer and results of a biopsy of her thyroid shows cancer, what's her prognosis?
When given 3 to 6 months prognosis, because of metastic breast cancer that has returned 3 times now to brain, what will the body/disease do as result?
It depends: The degree of control of the brain tumor is important. Although it has returned, the question is whether all avenues such as surgery, gamma knife or both have been used to control the brain tumors. With respect to the rest of the body, imaging/staging studies should be done to see how extensive the breast cancer is. That is, has it gone to the liver or lung or bone? That would make a big difference. ...Read more
My wife has stage for breast cancer that has now mets to the brain, the oncologist has said prognosis is 3 to 6 months. How have they determined thi?
Stats: Terribly sorry about your young wife. Brain metastases have a poor prognosis and are usually fatal. That number they gave you is just a statistical average that may or may not apply to her. Depends on many factors. No person can know how long any of us has to live. Be with her and make her as happy and comfortable as possible whether she lives a day or a hundred years. God bless both. ...Read more
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C, lumpectomy, rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. And at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
32 yo, breast cancer stage 1b, double mastectomy, micrometastasis in one lymph node. TCH treatment, followed by radiation. Prognosis thoughts????
Prognosis is good!: I would need more information to be definitive but with a small primary tumor (stage 1) and only micrometastasis in one node, your prognosis should be relatively good. Since you received TCH, it is obvious that you had her2 positive breast cancer so your prognosis is less favorable than had her2 not been positive. However, 5 year survival in excess of 85% is shown in recent studies with TCH. ...Read more
With metastic breast cancer (skeleton/no organ) moving into the csf, what is the prognosis? How much time is likely if it stays out of brain?
It depends: When metastatic breast cancer spreads to the csf, this is carcinomatous meningitis. The diagnosis is made by spinal tap analysis of CSF and by mri. Prognosis is dependent on the molecular markers on the breast cancer, the overall status of the metastatic disease (ie. How widespread) and the response to the chemotherapy. Treatment of the CSF is with intrathecal chemotherapy. ...Read more
Need prognosis for woman 75, stage 4 breast cancer, mets to (hip/knee bone): otherwise VERY healthful. Refuses treatment. Planning long RV trip soon!
Can't preduct: She should go on her trip and enjoy herself. There are lots of different kinds of breast cancer and even tumors of the same kind and at the same stage can kill in a short time or stay quiescent for years. Cherish every day you have together. ...Read more
My husband has breast cancer and now it's in spleen lung bones and heart muscle. What would be his prognosis? He is 50 years old
Twin sister has breast cancer. Says she has ductal AND lobular cancer. Surgery, chemo, radiation And hormone therapy after. Prognosis for this type?
Prognosis is Stage-b: The prognosis of breast Cancer is dependent on stage of her Cancer at the time of diagnosis. Most breast cancers are stage-1 or 2 and patients do very well, living near normal lives. Check in case she had stage-3 cancer....which does carry risk for recurrence in the future. I think she will do well over the next 5-10 years but needs to remain under surveillance as there is always some unpredictabi ...Read more
Yes: A woman with breast cancer in one breast is at a slightly higher rush of having it in the opposite breast. In some cancers, the risk is much higher. Biopsies should be able to confirm for you that any lump is benign. See your MD ...Read more
Bilateral nipple discharge with stimulation, cytology was negative, no lump or mass seen on u/s.Is this accurate test for breast cancer?
Sort of: Cytology is not a great test to rule out cancer in the case of nipple discharge. Ultrasound is a good test but also doesn't rule out cancer. However bilateral discharge, only with stimulation, is extremely unlikely to represent cancer, especially at your age. Unilateral, spontaneous discharge is more concerning, as is bloody nipple discharge. ...Read more
Axillary adenopathy: It would be very unlikely that breast CA would cause symmetrical and bilateral lymphnode swelling. Sounds much more likely to be an infectious/viral process. ...Read more
Is breast cancer risk increased with suspicious bilateral microcalcification clusters and large thickened nodule w/neg. Us? How much?
Walk B4 U Run: Breast microcalcifications are very common, some of which may be associated with cancer. Radiologists will deem those suspicious enough to warrant biopsy as "birads 4 or 5". If so, the next step is to have a (nonsurgical) biopsy for definitive diagnosis. A nodule seen on mammography but not on ultrasound will also be categorized as above. Your next step is to speak w/the dr. Who ordered the mamm. ...Read more
Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more