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Doctor insights on: Bevacizumab Medication

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Will avastin (bevacizumab) increase survival significantly for metastic colon cancer with liver mets? Is it a risky drug

Will avastin (bevacizumab) increase survival significantly for metastic colon cancer with liver mets? Is it a risky drug

Slight benefit: Bevacizumab (Avastin (bevacizumab)) is one of those drugs that is extremely expensive and often has limited benefit. Patients with metastatic colon cancer who received Avastin (bevacizumab) plus chemotherapy lived 1-2 months longer on average than those receiving chemo only. Because it has marginal benefit but costs ~$30, 000 the U.K. Health Service won't pay for it. It can cause skin rash, bleeding or wound healing problems. ...Read more

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Who should not use Bevacizumab injections?

Bevacizumab: None noted in Drugs. Com. See: http://www. Drugs. Com/pro/avastin. Html ...Read more

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How long is a woman usually on cytozen and avastin (bevacizumab)?

How long is a woman usually on cytozen and avastin (bevacizumab)?

Medication use: Avastin (bevacizumab) is a biologic used to interfere with new blood vessel growth in various tumors. It is not time-limited or sex-limited to females. The other drug is an Ayurvedic medicine and I can't comment on its use. ...Read more

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Can you have surgery while taking Avastin (bevacizumab)?

Can you have surgery while taking Avastin (bevacizumab)?

Avoid it, if it is p: Avastin (bevacizumab) causes interference in wound healing. So it is best to stop Avastin (bevacizumab) if you need to undergo surgery. It takes 4 to 6 weeks for the Avastin (bevacizumab) effects to go away after the last dose used. Then it is safer to do surgery. Your oncologist as well as your surgeon can/will guide you in this regard, if you have not already been told about it. ...Read more

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What affect does avastin (bevacizumab) have on fertility?

What affect does avastin (bevacizumab) have on fertility?

Possible menopause: Avastin (bevacizumab) is used to treat certain advanced cancers. It may cause ovarian failure (induced menopause), up to 34 percent of women in one study. However, this will reverse in 1/5 of women once Avastin is stopped. ...Read more

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I need some information about the mechanism of avastin (bevacizumab) on the body..

I need some information about the mechanism of avastin (bevacizumab) on the body..

Stops angiogenesis: Avastin (bevacizumab), and was the first commercially available angiogenesis inhibitor. Its main action is the inhibition of the function of a natural protein called vascular endothelial growth factor (vegf) that stimulates new blood vessel formation. Because most malignant tumors are highly dependant on angiogenesis to obtain a blood supply and nutrients Avastin can stop or delay growth. ...Read more

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What is the success of avastin (bevacizumab) for treating glioblastoma? Does it work?

What is the success of avastin (bevacizumab) for treating glioblastoma? Does it work?

Marginal: It is primarily being used to treat recurrent malignant gliomas. The latest results with its use as a frontline treatment for malignant glioma show no real benefit over the current conventional regimen using radiation therapy and chemotherapy with temodar (temozolomide). ...Read more

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My sister was diagnosed with atypical meningiomanow taking avastin (bevacizumab) what is her survival rate?

My sister was diagnosed with atypical meningiomanow taking avastin (bevacizumab) what is her survival rate?

Good: Meningiomas are usually benign tumors with excellent prognosis. Symptoms depends on the location of tumor. Atypical meningioma is more concerning and it is in a spectrum (worse than benign but better than malignant meningioma). The idea is to see the rate of growth, slow it if possible. If progressing, surgery, radiosurgery, or traditional radiation or combination of above are possible options. ...Read more

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Does avastin (bevacizumab) reduce male fertility?

Does avastin (bevacizumab) reduce male fertility?

No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here:

http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf. ...Read more

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How does avastin (bevacizumab) affect male fertility?

How does avastin (bevacizumab) affect male fertility?

It doesn't (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here:
http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf. ...Read more

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Do you know are avastin (bevacizumab) and Xeloda the same?

Do you know are avastin (bevacizumab) and Xeloda the same?

Different: Xeloda is oral chemotherapy while Avastin (bevacizumab) is a monoclonal antibody targeting vascular growth factor. Bevacizumab (avastin) is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor. It also helps with chemo by allowing entry into tumor microvascular structures while Xeloda helps to inhibit DNA synthesis ...Read more

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Which is more effective: Avastin (bevacizumab) or Erbitux?

Which is more effective: Avastin (bevacizumab) or Erbitux?

Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more

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Can avastin (bevacizumab) cause an increase of tumor markers?

Can avastin (bevacizumab) cause an increase of tumor markers?

Bevasizumab or: Avastin (bevacizumab) vies with vascular endothelial growth factor. It's action interferes with development or growth of blood vessels needed by tumors. Causes incresed blood pressure and bleeding as leading toxicity. No obvious reason that it should influence tumor markers. ...Read more

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What effect does avastin (bevacizumab) have on male fertility?

What effect does avastin (bevacizumab) have on male fertility?

Unsure: Avastin (bevacizumab) has shown to be deterimental to female reporuductive potential with up to 30-35% have serious complications (ovarian failure). To my knowledge there are no studies on men. Any chemotherapy has the potential risk of causing fertility issues in the future. You may want to consider freezing sperm with a sperm bank or your local reproductive endocrinologist. Also talk to your oncologist. ...Read more

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I have a history of atypical meningiomas, 2 of 4 were surgically removed & radiated, being treated now with avastin (bevacizumab).Need feedbk on the effectiveness?

I have a history of atypical meningiomas, 2 of 4 were surgically removed & radiated, being treated now with avastin (bevacizumab).Need feedbk on the effectiveness?

Malignant meningioma: Malignant meningiomas produce high levels of vascular endothelial growth factor (vegf)- this is what supports the use of avastin (bevacizumab).No clear data about the effectiveness of avastin (bevacizumab)-however a phase ii study on this topic is ongoing. At this time, the effectiveness is shown only on case reports as this one, published on clinical journal : http://annonc. Oxfordjournals. Org/content/21/12/2445.Full. D/w md. ...Read more

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What are your thoughts on avastin (bevacizumab) for ovarian cancer?

What are your thoughts on avastin (bevacizumab) for ovarian cancer?

Get the facts: You need a good relationship with at least two very ethical oncologists. You'll spend a huge amount of your or someone else's money for a treatment that makes the cancer stay smaller but probably doesn't prolong life and puts you at risk for death from massive hemorrhage. In the process, you will be adding to scientific knowledge. Informed consent rules; you decide. ...Read more

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Using avastin (bevacizumab) for macula degeneration treatment?

Using avastin (bevacizumab) for macula degeneration treatment?

Avastin (bevacizumab): Avastin (bevacizumab) is a drug that is commonly used in the treatment of wet macular degeneration and other eye conditions involving leakage of fluid from blood vessels in the retina. ...Read more

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How effective are Bevacizumab injections for treating lung cancer?

How effective are Bevacizumab injections for treating lung cancer?

Beneficial: Bevacizumab injections have been used to treat Glioblastoma, Metastatic Colorectal Cancer, Non–Small Cell Lung Cancer (NSCLC) & Metastatic Kidney Cancer (mRCC). SEE: http://www. Avastin. Com/patient ...Read more

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How is avastin (bevacizumab) affecting my blood glucose level?

How is avastin (bevacizumab) affecting my blood glucose level?

No direct relation: Avastin (bevacizumab)'s main function is to inhibit blood vessel formation. Due to importance of blood vessel formation in wound healing, it can cause potential complications after surgery. Avastin (bevacizumab) can also increase protein leakage from the kidneys, increase blood pressure, or risk of clots or bleeding. Avastin (bevacizumab) is used in treatment of certain cancers and certain eye conditions. It is an antibody; not chemo. ...Read more

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Does medicare cover avastin (bevacizumab) injections for degeneration of the macula?

Does medicare cover avastin (bevacizumab) injections for degeneration of the macula?

Yes: Medicare does cover this treatment as it is considered medically necessary. ...Read more

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Does avastin (bevacizumab) for hemi retinal vein occlusion work well?

Does avastin (bevacizumab) for hemi retinal vein occlusion work well?

Yes: It work well for retinal edema of the macula caused by retinal vein occlusions (central, hemi, and branch). Speak to your retinal specialist about this. ...Read more

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Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more

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How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

Better than chemo: Combining bevacizumab (BV)—a recombinant, humanized mAb targeting VEGF with irinotecan, fluorouracil (FU), and leucovorin (LV; IFL) has increased survival of patients with metastatic colorectal Ca compared with IFL It appears necessary to use combination therapy in treatment and has supported the concept that the use of immunochemotherapy improves results over chemo alone. ...Read more

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What can I do if my father is asked to take avastin (bevacizumab) injection for retina damage/ nerves block. Is it safe?

What can I do if my father is asked to take avastin (bevacizumab) injection for retina damage/ nerves block. Is it safe?

Safer than blindness: If Avastin (bevacizumab) has been advised, it is likely because of the presence of blinding disorder such as macular degeneration. Although there is risk with drugs injected into the eye, the risk of blindness from not treating is substantially higher. Discuss your concern with his ophthalmologist. ...Read more

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Is it safe or beneficial to take prolensa a day prior and the day of an Avastin (bevacizumab) shot for macular degeneration?

Is it safe or beneficial to take prolensa a day prior and the day of an Avastin (bevacizumab) shot for macular degeneration?

Bromfenac: Prolensa (. Bromfrnac, Xibrom) is a NSAID. It is used to reduce pain and inflammation following eye surgery.
I prefer to have patients start a day prior to procedure and continue after the procedure as needed twice daily. Usually for two weeks but could be longer. Taking it on the day of the procedure is also recommended. ...Read more

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Are there any meningioma clinical trials/studies available? I have had 2 of 4 tumors removed. On avastin (bevacizumab) infusions now. 48 yr old/ black/female

Yes: There are clinical trials for meningioma. Please read here:
http://clinicaltrials. Gov/ct2/results? Term=meningioma&search=search

discuss with your doctor if you are a candidate for trial. ...Read more

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Tx is bi-weekly with fu5 + avastin (bevacizumab). Cea is reliable, tested at start of tx. Cea drops significantly with neulasta/neopogen tx following chemo. Why?

Tx is bi-weekly with fu5 + avastin (bevacizumab). Cea is reliable, tested at start of tx. Cea drops significantly with neulasta/neopogen tx following chemo. Why?

Unclear question: Cea dropping is due to chemotherapy. It is a good sign, indicates chemo is working. Neupogen/neulasta are given to increase white cell counts. These are probably unnecessary if you are only taking f-5-fu based chemo. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years (some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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On Eribulin & Avastin (bevacizumab). Coughing like crazy, dry cough not in lungs. Tried Syrup with Codeine, 100 mg Tesalon Perles. Is there anything else I can try?

On Eribulin & Avastin (bevacizumab). Coughing like crazy, dry cough not in lungs. Tried Syrup with Codeine, 100 mg Tesalon Perles. Is there anything else I can try?

Steam Inhalation: Steam provides moist air and as well as loosen congestion and remove irritants from the throat and lungs. 3-4 times per day is recommended. ...Read more

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How does avastin (bevacizumab) for eye complication treatment work?

How does avastin (bevacizumab) for eye complication treatment work?

Anti VEGF: Avastin (bevacizumab) is a medication (originally for cancer) that helps prevent new blood vessel growth by inhibiting a certain blood vessel growth factor. Thus it is commonly used in the eye now to prevent neovascularization and swelling associated with abnormal new leaky blood vessels. ...Read more

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How can the shot of avastin (bevacizumab) in eye complication treatment work?

How can the shot of avastin (bevacizumab) in eye complication treatment work?

Anti-VEGF: Avastin (bevacizumab) is a chemically modified antibody that inactivates all forms of vascular endothelial growth factor, vegf. Vegf are chemical signals that cause blood vessels to leak lead in grow where they don't belong. Injecting Avastin (bevacizumab) to the eye helps to treat blinding conditions such as macular degeneration, diabetes, vein occlusions, retinopathy of prematurity & swelling from inflammation. ...Read more

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How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

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