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Doctor insights on: Bevacizumab

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Using avastin (bevacizumab) for macula degeneration treatment?

Using avastin (bevacizumab) for macula degeneration treatment?

Avastin (bevacizumab): Avastin (bevacizumab) is a drug that is commonly used in the treatment of wet macular degeneration and other eye conditions involving leakage of fluid from blood vessels in the retina. ...Read more

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I need some information about the mechanism of avastin (bevacizumab) on the body..

I need some information about the mechanism of avastin (bevacizumab) on the body..

Stops angiogenesis : Avastin (bevacizumab), and was the first commercially available angiogenesis inhibitor. Its main action is the inhibition of the function of a natural protein called vascular endothelial growth factor (vegf) that stimulates new blood vessel formation. Because most malignant tumors are highly dependant on angiogenesis to obtain a blood supply and nutrients Avastin can stop or delay growth. ...Read more

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Does avastin (bevacizumab) reduce male fertility?

Does avastin (bevacizumab) reduce male fertility?

No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but i don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www.Gene.Com/gene/products/information/pdf/avastin-prescribing.Pdf. ...Read more

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Which is more effective: Avastin (bevacizumab) or Erbitux?

Which is more effective: Avastin (bevacizumab)  or Erbitux?

Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more

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Is cytoxan (cyclophosphamide) chemotherapy?

Is cytoxan (cyclophosphamide) chemotherapy?

Yes.: Generic name of Cytoxan is cyclophosphamide. It is a drug commonly used to treat a variety of cancers, but may also be used to treat some autoimmune disorders, such as lupus. ...Read more

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How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

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Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more

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Does avastin (bevacizumab) reduce male fertility?

No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but i don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www.Gene.Com/gene/products/information/pdf/avastin-prescribing.Pdf. ...Read more

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How does avastin (bevacizumab) affect male fertility?

How does avastin (bevacizumab) affect male fertility?

It doesn't (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but i don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www.Gene.Com/gene/products/information/pdf/avastin-prescribing.Pdf. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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How does avastin (bevacizumab) for eye complication treatment work?

How does avastin (bevacizumab) for eye complication treatment work?

Anti VEGF: Avastin (bevacizumab) is a medication (originally for cancer) that helps prevent new blood vessel growth by inhibiting a certain blood vessel growth factor. Thus it is commonly used in the eye now to prevent neovascularization and swelling associated with abnormal new leaky blood vessels. ...Read more

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Does Taxol (paclitaxel) stabilize microtubules?

Does Taxol (paclitaxel) stabilize microtubules?

Taxol (paclitaxel): Yes. You can read about this "Insights into the mechanism of microtubule stabilization by Taxol" See: http://www.pnas.org/content/103/27/10166.full ...Read more

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49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?

49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?

It varies according : Patients with stage 4 lung cancer have an average survival of 12 months but there is a wide range from 9 months to 18 months. Some patients can live for 2-5 years but that is rare and only happens if their tumor shows a great response to chemotherapy. ...Read more

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Does avastin (bevacizumab) for hemi retinal vein occlusion work well?

Does avastin (bevacizumab) for hemi retinal vein occlusion work well?

Yes: It work well for retinal edema of the macula caused by retinal vein occlusions (central, hemi, and branch). Speak to your retinal specialist about this. ...Read more

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Can avastin (bevacizumab) cause an increase of tumor markers?

Can avastin (bevacizumab) cause an increase of tumor markers?

Bevasizumab or: Avastin (bevacizumab) vies with vascular endothelial growth factor. It's action interferes with development or growth of blood vessels needed by tumors. Causes incresed blood pressure and bleeding as leading toxicity. No obvious reason that it should influence tumor markers. ...Read more

Dr. Liawaty Ho Dr. Ho
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Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Dr. Liawaty Ho Dr. Ho
8 doctors agreed:
Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you. ...Read more

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Is it safe or beneficial to take prolensa a day prior and the day of an Avastin (bevacizumab) shot for macular degeneration?

Is it safe or beneficial to take prolensa a day prior and the day of  an Avastin (bevacizumab) shot for macular degeneration?

Bromfenac: Prolensa (. Bromfrnac,Xibrom) is a NSAID. It is used to reduce pain and inflammation following eye surgery. I prefer to have patients start a day prior to procedure and continue after the procedure as needed twice daily. Usually for two weeks but could be longer. Taking it on the day of the procedure is also recommended. ...Read more

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Does avastin (bevacizumab) for hemi retinal vein occlusion work well?

Yes: It work well for retinal edema of the macula caused by retinal vein occlusions (central, hemi, and branch). Speak to your retinal specialist about this. ...Read more