Doctor insights on:
Beta Thalassemia Trait
Can a female with Hb H disease marry someone with beta thalassemia trait? What are the possible results in terms of genetics percentages?
Sure: Anybody can marry anybody. Since HgbH disease involves the alpha genes and beta thal minor involves the beta genes, I would not be concerned. However, you might do well to be certain that neither partner carries the other person's trait as well masked by what's already diagnosed. Sit down with a competent clinical geneticist. ...Read more
Yes, but unlikely: A person with beta thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more difficult time making hemoglobin (to make new red blood cells), he may not wish to be a blood donor. ...Read moreSee 1 more doctor answer
I hv beta thalassemia trait. Lived with terrible lethargy all my life. Anyway I can overcome this problem?
Need more info: What is your hemoglobin level? Beta thalassemia trait usually does not cause severe enough anemia to result in lethargy. It is likely that there is some other explanation for your symptoms. It would be prudent to consult a doctor for an evaluation and to exclude depression. ...Read more
My 6 yo had appt w/ hematology. Results show elevated ldh, elevated retic and increased hgb F. Is this consistent with beta thalassemia trait?
I'm 16, have PCOS,had long periods last month,recently got diagnosed microcytic hypochromic anemia & beta thalassemia trait. Are these all related?
I am in 8 weeks pregnancy and i have thalassemia minor and my husband have Beta thalassemia trait.So is there any problem in my pregnancy.
Depends what type u: depends on what kind of thallasemia minor you have,alpha or beta.If you have thallasemia beta minor,that makes you carrier of the bea thallasemia gene Thallasemia trait is same as thalassemia minor,carries gene for beta thallasemia You both have to tested if not already done, discuss with your Obstetrician about the outcome. If both carriers 1/4 chance of baby with Thallasemia,1/4normal,2/4 normal ...Read more
If anemic, no: The red cross won't let people who are anemic donate blood. People are checked for anemia at their screening for blood donation, and if your hemoglobin is less than 12.5 they will not allow you to donate blood. Not everyone with beta thalassemia trait is anemic, so there is a chance that you may pass the screening. However, if you know that you often have a low hemoglobin, expect to be turned away. ...Read moreSee 1 more doctor answer
Genetic disorder: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3237252/ "the disorder is characterized by marked clinical variability, ranging from a mild and asymptomatic anaemia to a life-threatening disorder requiring transfusions from infancy. "...."careful tailoring of treatment is required for each patient, and that therapeutic approaches should be re-assessed over-time." not curable..Look at website-. ...Read more
What will be the result of our current and future baby bcoz my husband have e trait and i've beta thalassemia minor.
See below: 25 % (1 in 4) chance with each pregnancy of having a child with HGB e/beta thal disease. It is a lifelong illness that can result in serious health problems. Possible outcomes with pregnancy: 25 % chance of having child w/hgb e trait 25 % chance of having child w/beta thal minor/trait 25 % chance of having child hemoglobin e/beta thal disease 25 % chance of having child w/o trait/disease. ...Read more
I have thalassemia minor (beta thalassemia) and my fiance also has traits of beta thalassemia... Can we have normal children?
Find out: Your fiance needs to be tested as well and you both need to sit down with a genetic counselor in any case. It's not just "can we have normal children?" the real question, "do we want to knowingly run the risk of 1 out of 4 of each of our children being born with a god-awful case of beta-thal major? What are our options? Are they acceptable to us?" this is a very grave matter. ...Read more
My husband have e trait and I have beta thalassemia minor and we have 1 child.What will be the result of our current and future baby?
I've beta thalassemia minor and my husband have e trait. Is it necessary to test our baby? Is there any chances to get disease of our baby?
Not likely: Unless your infant is showing signs of anemia, you may do an hemoglobin electrophoresis at any time after several months of life. Fetal hemoglobin (normal) is usually present in decreasing amounts until around 18 months. Once the electrophoresis is done, you will know your baby's hemoglobin type. Discuss with your doctor. ...Read moreSee 1 more doctor answer
My husband have e trait and i've beta thalassemia minor and we have 1 child.After which month we will test our baby?Now she have passed 3 months.
How do we know which baby will be suffered from hgb e/beta thal disease? Any chances about my 1st baby?Bcoz we are e trait and beta thalassemia couple
It's random: Each time you conceive a child, a random assortment of genes from each parent goes into making up junior's genome. This is basic biology but still often needs to be reviewed. It's good for folks with any thal variant to take enough folate, (folic acid) but you should be taking that iron if and only if you are actually iron deficient or clearly need to supplement. Glad you're learning and proactive. Good luck. ...Read more
I have thalassemia minor beta trait. I am married to my 1st cousin. He doesn't have any trait of thal. What are the chances for us having normal kids?
Is there any danger to get 2nd time pregnency? Bcoz i've beta thalassemia minor and my husband have e trait.
Likely no: It sounds like you've educated yourself on your condition beta thallesemia minor. Plenty of women have successful pregnancies with this condition all the time. I wasn't sure what you meant when you said your husband has e trait? If you have any questions, consult a perinatologist. They are the best doctors for managing high-risk pregnancy. ...Read more
After conceive is it possible to know is my baby affected or carrier by thalassemia? Bcoz i've beta thalassemia minor and my husband have e trait.
Possible: More information is needed about your and your husband's genetic make up to know if the baby will inherit it, but to answer "possible or not" i will say "possible" until further data is presented. ...Read more
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