Doctor insights on:
Beta Thalassemia Connected To Kidney Disease
Yes: Beta thalassemia disease is prevented if beta thal carriers do not have children with one another (if they have children together, some children will be normal, some carriers, and some have disease). The other, less desirable way, is to test fetuses during pregnancy and abort the fetuses who have beta thal major. ...Read more
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
Can a female with Hb H disease marry someone with beta thalassemia trait? What are the possible results in terms of genetics percentages?
Sure: Anybody can marry anybody. Since HgbH disease involves the alpha genes and beta thal minor involves the beta genes, I would not be concerned. However, you might do well to be certain that neither partner carries the other person's trait as well masked by what's already diagnosed. Sit down with a competent clinical geneticist. ...Read more
Bit of a stretch but: OK....I can understand why your doctor would say that because CKD can in fact cause peripheral neuropathies which is the likely mechanism behind the tinnitus. But it's certainly not anywhere close to the most common symptoms. Has your doctor looked at other causes such as medications, infection, and of course the most common cause, hearing loss....Huh? HEARING LOSS! ...Read more
Genetic disorder: Http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/pmc3237252/ "the disorder is characterized by marked clinical variability, ranging from a mild and asymptomatic anaemia to a life-threatening disorder requiring transfusions from infancy. "...."careful tailoring of treatment is required for each patient, and that therapeutic approaches should be re-assessed over-time." not curable. Look at website-. ...Read more
No: The normal parent will give his or her normal gene to their baby. That means the baby will have one abnormal and one normal gene, meaning the baby would be a "carrier" of one bad gene and not suffer the actual disease. The only way the baby would end up with 2 abnormal genes is if the gene from the normal parent got altered by a new mutation... Which is unlikely to happen. ...Read more
I've beta thalassemia minor and my husband have e trait. Is it necessary to test our baby? Is there any chances to get disease of our baby?
Not likely: Unless your infant is showing signs of anemia, you may do an hemoglobin electrophoresis at any time after several months of life. Fetal hemoglobin (normal) is usually present in decreasing amounts until around 18 months. Once the electrophoresis is done, you will know your baby's hemoglobin type. Discuss with your doctor. ...Read more
Epilepsy and e beta thalassemia are related? Is Epilepsy occurred for thalassemia? If someone have both diseases then what will be the effect?
How do we know which baby will be suffered from hgb e/beta thal disease? Any chances about my 1st baby? Bcoz we are e trait and beta thalassemia couple
It's random: Each time you conceive a child, a random assortment of genes from each parent goes into making up junior's genome. This is basic biology but still often needs to be reviewed. It's good for folks with any thal variant to take enough folate, (folic acid) but you should be taking that iron if and only if you are actually iron deficient or clearly need to supplement. Glad you're learning and proactive. Good luck. ...Read more
Ct scan showed Small vessel Ischemia. Cardioglogist quadruppled beta blocker after EKG. How does the ischemia effect my Kidney disease (stage 4)?
Vessels in both:
Without an actual exam, I can't give specific medical advice on your particular health.
Same things affect vessels EVERYWHERE. So, while strokes, or heart attacks don't hit the kidney. The same bad vessels are in all organs. Hi BP, diabetes, and cholesterol all clog vessels everywhere and affect all the organs (heart, brain, kidney). Treatable.
such bad heart disease, no blood gets to kidney. ...Read more
Probably not: According to the literature, beta thalassemia is not known to cause seizures. Ask your doctor to be sure. For information, visit http://www. Uptodate. Com/contents/thalassemia-the-basics. ...Read more
My baby've hb e/beta thalassemia & seizure disorder. Doctor said no medicine need for seizure. Proper transfusion will solve the seizure. Pls advice.
Vague: Kidney failure is notorious for causing very vague nebulous symptoms sometimes like, fatigue, insomnia, nausea, decreased appetite, metallic taste in the mouth, etc. I have a more comprehensive list on my blog at http://www. Kidneydoctorbradenton. Org/2013/04/what-are-signs-and-symptoms-of-ckd. Html. ...Read more
Indirectly: Garlic tends to lower body cholesterol and inflammation, thus blood flow to kidneys may improve slightly by keeping arteries to kidneys somewhat cleaner. May also reduce any inflammatory swelling in kidneys as in pyelonephritis. Otherwise, in itself does not dieectly treat kidney disease. ...Read more
Heavy Metals: The extent of kidney damage caused by heavy metals depends on the dose, route and duration of exposure. Cadmium (Cd), mercury (Hg), lead (Pb), platinum (Pt), and Chromium (Cr) and they can cause heavy metal nephropathy and the severity could range from tubular dysfunction to renal failure/death. ...Read more
Asymptomatic: It depends on the cause of the kidney disease. Some may present with swelling of the legs, face, others with blood tinged urine, however most often, early kidney disease are asymptomatic. Protein in the urine is one of the earliset signs of kidney disease followed by increase in serum creatinine on blood tests. If you suspect, please see your doctor to get the blood and urine tests. ...Read more
None: No known herbs for kidney disease. Based on your baseline kidney function anything such as a mega dose of vitamin C or a large dose of Mg or phosphate containing laxative could be dangerous for remaining kidney health. There is an increase incidence of Chinese herbal nephropathy. Before using anything checks your kidney function and check with your doctor. ...Read more
Blood and urine: Urinalysis with tests for protein, glucose, blood, bilirubin, pH and specific gravity, blood tests for na, k, cl, creatinine, urea, bicarbonate (sodium bicarbonate) are a good starting point. Many other tests may be needed depending on these chemistry tests as well as hematology and urine microscopy, ultrasound and serologic testing. ...Read more
No herbs: There is no sufficient evidence by research studies to recommend any herbs to prevent or cure kidney disease. However there are studies showing herbs can cause kidney disease. It is best to show the herbal supplements to your doctor to advise you. In my opinion, no herbal product is safe as there are no safety studies with many of the herbal products. ...Read more
See below: Mpgn is short for membranoproliferative glomerulonephritis.This is a pattern of kidney injury seen on kidney biopsy. High blood pressure, swelling of legs all whole body and loss of kidney function with more symptoms like anorexia, nausea depending on stage of kidney function loss. ...Read more
Tylenol (acetaminophen): If you have kidney disease, nsaids like alleve and Advil can further worsen your kidney disease or increase your blood pressure. Therefore these medicines should be avoided in patients with ckd. If you have pain, tylenol (acetaminophen) would be your safest option. ...Read more
There are many: The list is as long as your arm. In general kidney disease is something your were born with-congenital, or was acquired later in life. Hypertension and diabetes are the two systemic diseases that most affect the kidneys. Infections, stones, obstructions, trauma, and inflammations--glomerulonephritis are also common causes of kidney disease. ...Read more
Serum Creatinine: The serum creatinine is used to estimate kidney function. This information is present on all labs identified as the eGFR. Normal is >90, Stage 1 >90 with urine protein present, Stage 2 60-90, Stage 3 30-59, Stage 4 15-29, Stage 5 <15, Stage 6 on dialysis. The eGFR is an estimate and the real function is generally +/- 50% of the number. Example eGFR 30 could really be anywhere from 15-45. ...Read more
Often no syptoms: Most often it is asymptomatic.Symptoms depends on the cause of kidney and severity of kidney disease. Common symptoms are leg and facial swelling, fatigue, changes in appetite, shortness of breath etc. Docs often want to diagnose chronic kidney disaese in early reversible stages before symptoms develop. Please consult your doc ...Read more