Top
40
Doctor insights on: Beta Globulin Range

Share
1

1
What is the implication of elevated Beta Globulin?

What is the implication of elevated Beta Globulin?

Nothing by itself: Trivial elevations seen on serum protein electrophoresis reflect normal human variability. Very high transferrin in iron deficiency can raise beta globulin into a spike. Rare IgA monoclonal gammopathies can make a spike here. Otherwise, ignore it. ...Read more

2

2
What condition presents w/:wbc4.82 rbc3.57 hgb11.3 hct33.4, rdw-cv11.6, mpv8.4, neutro40.3%, lympho11.2%sedrate33, rf12, beta-globulin 1.3, a/g ratio 0.9?

What condition presents w/:wbc4.82 rbc3.57 hgb11.3 hct33.4, rdw-cv11.6, mpv8.4, neutro40.3%, lympho11.2%sedrate33, rf12, beta-globulin 1.3, a/g ratio 0.9?

Out of Context: I am sorry but you cannot just give us a report of the blood cells without any history or context and except a specific diagnosis. There are thousands or possibilities or variables at play here. ...Read more

4

4
What condition presents w/:wbc4.82 rbc3.57 hgb11.3 hct33.4, rdw-cv11.6, mpv8.4, neutro40.3%, lympho11.2%, mono0.54%, eosino2.5%, baso0.6%, sedrate 33, CRP 0.2, rf 12, beta-globulin 1.3, a/g 0.9&hi folate (folic acid)?

What condition presents w/:wbc4.82 rbc3.57 hgb11.3 hct33.4, rdw-cv11.6, mpv8.4, neutro40.3%, lympho11.2%, mono0.54%, eosino2.5%, baso0.6%, sedrate 33, CRP 0.2, rf 12, beta-globulin 1.3, a/g 0.9&hi folate (folic acid)?

Asking 4 impossible: This is not in any way how medicine works. Please read the first response and reply with some context of symptoms or why these tests were run. There are a thousand possibilities. ...Read more

5

5
What can cause elevated alkaline phosphatase, beta globulin, TIBC, Compliment 3 +4, C-react. Protein and low ferritin, MCV, MCG and iron saturation?

What can cause elevated alkaline phosphatase, beta globulin, TIBC, Compliment 3 +4, C-react. Protein and low ferritin, MCV, MCG and iron saturation?

Low iron: Elevated alk phos is seen with liver and bone disorder. Iron deficiency is suspected, but chronic inflammation may cause most of the lab abnormalities. A hematologist could shed some light on these varied lab abnormalities. Collaboration with a rheumatologist would also be helpful to identify a chronic inflammatory process. ...Read more

7

7
Why would an immunologist put me on bactrim (sulfamethoxazole and trimethoprim) for a whole year? Should I take probiotic with them? I am 53 years old and have low beta globulin.

Why would an immunologist put me on bactrim (sulfamethoxazole and trimethoprim) for a whole year? Should I take probiotic with them? I am 53 years old and have low beta globulin.

Bactrim (sulfamethoxazole and trimethoprim): Bactrim (sulfamethoxazole and trimethoprim) has been used for prevention of urinary tract infections. This approach is being used less these days for several reasons. Treatment for a whole year seems surprising even if your immunoglobulins (gamma globulin) are low. If you have had lots of certain infections maybe he want to prevent more. But the likelihood of getting resistance is high with chronic use of most antibiotics. Bactrim (sulfamethoxazole and trimethoprim) has been used and proven beneficial for prevention of pneumocystis pneumonia. Many immunologists might use antibiotic at the first sign of infection. Ask him/her what the evidence is for this therapy, its pros and cons. Nothing wrong with taking a probiotic with this. ...Read more

8

8
Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?

Complicated: When I was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more

10

10
Hi I got results back from testing and was surprised to find something wasn't in range. With my A1c at 6.2 and globulin at 3.7. What do you advise?

Hi I got results back from testing and was surprised to find something wasn't in range. With my A1c at 6.2 and globulin at 3.7. What do you advise?

Normal ranges: These tests are close to the normal range cut-offs, so since by definition a small percentage of normal people will still have test values outside the 'normal' range, you may have nothing to worry about. Typically borderline abnormal tests lead to follow-up testing to verify, and then to more serious investigation for disease. If you feel well, repeat testing in a few months may be appropriate. ...Read more

11

11
Globulin was in range. I changed my diet for the good to fix alt. Which worked and in 1 week the g went to 1.6. Army won't sign me if it won't go norm?

Globulin was in range. I changed my diet for the good to fix alt. Which worked and in 1 week the g went to 1.6. Army won't sign me if it won't go norm?

Complex case: Without evaluating you, it's very difficult to say. Depends on the cause of increased ALT, and what you did with your diet. If cause was excessive alcohol, then abstaining should be all that it takes, and returning a healthy protein diet may be sufficient to restore your normal globulin levels. ...Read more

12

12
Is beta-2-micro globulin typically elevated in lymphoma patients?

Is beta-2-micro globulin typically elevated in lymphoma patients?

A prognositic factor: Levels are incorporated into staging system for multiple myeloma. Higher levels in 75% cases can correlated with higher tumor burden. ...Read more

13

13
Beta-1 globulin 5.5 g/l and beta-2 globulin 4.9 g/l. My doc couldn't explain these results to me?

Dr needs to answer: The doctor that orders a test should have a good reason for ordering it and should understand how to interpret the results. Sounds like communication between you and your doctor could improve. These results won't mean anything to someone who doesn't know why it was ordered and doesn't have the rest of your medical and information. Tell your doctor you still have questions. ...Read more

14

14
Cretanine level is 1.27 (range is 1.25) & globulin is 3.7 (range is 3.5).Am diabetic for many years. What does it show. Any med to reduce. Is it to worry?

Cretanine level is 1.27 (range is 1.25) & globulin is 3.7 (range is 3.5).Am diabetic for many years. What does it show. Any med to reduce. Is it to worry?

Likely mild renal in: PT HAS RENAL INSUFFICIENCY. NEEDS FURTHER EVALUATION OF RENAL STATUS, IE CHECK UFINE FOR MICROALBUMINURIA, eGFR. PT WOULD BENEFIT FROM ACEI IE LISINOPRIL. IF PT IS ON METFORMIN NEEDS TO STOP MED. MAY WORSEN RENAL STATUS. ...Read more

15

15
What does it mean when protein syrum Beta 2 Globulin are high with beta gamma bridging?

What does it mean when protein syrum Beta 2 Globulin are high with beta gamma bridging?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the pattern could be due to liver disease, chronic inflammation in the intestine or neoplastic proliferation of plasma cells. Discuss it with the doctor who ordered the test. ...Read more

16

16
Protein & globulin have gone down each time a little in last two bloodwork still normal range but should I be concerned?

Protein & globulin have gone down each time a little in last two bloodwork still normal range but should I be concerned?

Bloodwork: Hi, greetings from skokie. As long as your blood work is in the normal range, I wouldn't worry. ...Read more

17

17
Female: protein total serum is 8.3, and range is 6.1 - 8.1. Globulin is 3.8, and range is 1.9 - 3.7. Should I be worried?

Female: protein total serum is 8.3, and range is 6.1 - 8.1. Globulin is 3.8, and range is 1.9 - 3.7. Should I be worried?

Probably not.: This small variation from normal is probably non-specific and not pathologic. Your doctor may want to repeat those tests in 2-3 months, and if the abnormality is more prominent, get a protein electrophoresis. ...Read more

18

18
What is the normal range for urine albumin/globulin ratio?

What is the normal range for urine albumin/globulin ratio?

No such thing: Serum Albumin globulin ratio may be used, but it is better to look at individual levels of each protein rather than ratios. There is no valid reason to look for Albumin globulin ratio in urine. ...Read more

19

19
Can a simple infection cause gamma globulin levels to decrease below normal range? (0.37 when normal is 0.7-1.6)?

Can a simple infection cause gamma globulin levels to decrease below normal range? (0.37 when normal is 0.7-1.6)?

No: Very unlikely, unless the patient is already immune compromised, main causes for this low level would be diseases/disorders leading to loss of protein from gut/kidneys or malnutrition. Low level of immunoglobulins has other causes though, lymphocytes problems, either T cells or B lymphocytes, that lead to immunodeficiency states, wish you wellness ...Read more

20

20
Direct bilirubin is 0.3 (rangeis 0-0.2), globulin-3.6 (range is 2.3-3.5) a/g ratio is 1.19 (range-120-2). Cbc is normal. Plz advise

Direct bilirubin is 0.3 (rangeis 0-0.2), globulin-3.6 (range is 2.3-3.5) a/g ratio is 1.19 (range-120-2). Cbc is normal. Plz advise

Get with your doctor: The only concern I have here is the slight elevation in direct bilirubin. I'm also going to assume it's new; some folks always run it at this level because of their biology. It won't hurt you but may be a warning, most likely that some medication giving you cholestasis. ...Read more

21

21
I recently received blood results showing gamma globulin levels of 0.37 when normal range is 0.7-1.6. Is it possible that this is a one-time thing?

I recently received blood results showing gamma globulin levels of 0.37 when normal range is 0.7-1.6. Is it possible that this is a one-time thing?

Maybe: Reference ranges are set so that several percent of healthy folks fall outside on either side. This may just be you. It is no danger. Stop worrying. If this continues or you are very curious, you can get the various types quantitated. Some folks run way-low on one of the three major types. Usually they still do okay. ...Read more

22

22
Y albumin 3.9 and the normal range for albumin is 4.8 at my lab so it mean that globulin level is high so could it be high because multiple meanloma?

Not likely: You can not tell that you have increased globulin by Albumin alone, you will need a total protein to see that.

18 year olds very very very rarely have myeloma. This Albumin is not so low, check both labs again and stop worrying. ...Read more

23

23
Gamma globulin level in test is 22.6%, results page they gave says this is higher than normal, normal range is listed as 11.1-18.8%. Concerned Myeloma?

Gamma globulin level in test is 22.6%, results page they gave says this is higher than normal, normal range is listed as 11.1-18.8%. Concerned Myeloma?

Means nothing: Reference ranges are set so that several percent of healthy folks fall outside on either end. This has actually happened to me as well. At age 27 you do not have myeloma, and even myeloma patients usually suppress the other gamma globulins. ...Read more

24

24
Hi, blood test results back and my globulin levels are 37g/l and believe this is above range- what can it mean? My albumin levels are 38g/l

Hi, blood test results back and my globulin levels are 37g/l and believe this is above range- what can it mean? My albumin levels are 38g/l

Insufficient info: There are many components in the fraction called globulin and you need serum protein electrophoresis and may be immunofixation to resolve the identity of the protein that is increased. ...Read more

27

27
Albumin 3.9 globulin 4.2 could this means multiple myeloma! Other blood test were within normal range?

Albumin 3.9 globulin 4.2 could this means multiple myeloma! Other blood test were within normal range?

Stop worrying: If you're otherwise feeling well, the chances of this being myeloma are remote. Reference ranges are set so that several percent of healthies fall outside on either end. ...Read more

28

28
Is 1.7 globulin level (ref range 1.9-3.7) a reason to be concerned? Total protein is 6.3 and albumin 4.6 are normal.

Not by itself: Much more important than the value itself, which is borderline low would be 1. The reason for why you had the test, symptoms versus regular checkup and 2. The trend, is there a previous value to compare with? Otherwise would not worry. Best would be to contact the physician who ordered the test. ...Read more

29

29
Albumin PEP 3.7, Alpha-1-Globulins: 0.3 (0.1-0.4), 
 Alpha-2: 0.9 (0.6-1.2), 
 Beta: 1.6 (0.7-1.3), Gamma 1.2 (0.6-1.7). Is it ok that my Beta is high?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, serum protein electrophoresis result gives more information by visual inspection and some times a follow-up test may be done depending on the pattern. Okay or not depends on what component of beta is high. Visit this site: http://www. Aafp. Org/afp/2005/0101/p105.html ...Read more

30

30
I want a hematologist opinion please why Wud there be a m spike when proteins albumin globulins ag ratio are in good ranges pls kindly let me knw? Plsl

SPEP: A monoclonal (M) protein "spike" can occur with a normal albumin and normal immunoglobulin (Ig, eg IgA, IgG, IgM) levels. A monoclonal gammopathy of undetermined significance (MGUS) can be further evaluated for smoldering multiple myeloma (SMM) or symptomatic MM with additional tests. MM patients may have CRAB findings - hyperCalcemia, Renal (kidney) insufficiency, Anemia, and Bone problems. ...Read more

31

31
I am a hepb carrier. My liver panel is as follows: pt high 9.1 (range 6.4-8.2), globulin high 4.9 (2.2-4.2), ag ratio low 0.9 (1.0-2.5) and everything else is normal. Do I need to worry?

I am a hepb carrier. My liver panel is as follows: pt high 9.1 (range 6.4-8.2), globulin high 4.9 (2.2-4.2), ag ratio low 0.9 (1.0-2.5) and everything else is normal. Do I need to worry?

See below: Low a/g ratio reflects liver disease. Elevated pt indicates blood takes longer time to clot; so u r at greater risk of prolonged bleeding or easy bruising. Doc handling your case may recommend vitamin k supplement or prescribe vitamin k to prevent bleeding from minor injuries. ...Read more

32

32
My blood work, my cmp is 8.8, globulin 4.7, A/G ratio 0.9, and my beta hCG is less than 5. im a 46 yr. Old female. Is this normal?

My blood work, my cmp is 8.8, globulin 4.7, A/G ratio 0.9, and my beta hCG is less than 5. im a 46 yr. Old female. Is this normal?

Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you have not provided complete data. CMP has more than 10 component tests. It would be prudent to discuss the results with your doctor. ...Read more

33

33
I want a hematologist opinion pls tel me why n how is there a m spike when protein albumin globulin ag ratio all are in good range?

See explanation: An M spike describes a monoclone (single type) of immunoglobulin. (Ig) If the rest of the normal globulins are low, but there is an excess of one type of Ig, then the ratio of albumin to (total) globuline can still be normal despite presence of an M spike. ...Read more

34

34
What could be the cause of a low calcium level of 8.2? Albumin 4.6, Globulin 1.8, BUN 16, Vit D 38. Sodium slightly elevated but all else in range

What could be the cause of a low calcium level of 8.2? Albumin 4.6, Globulin 1.8, BUN 16, Vit D 38. Sodium slightly elevated but all else in range

Calcium: What is your ionized calcium level? Why skin biopsy? And what other medications are you taking ie for depression and anxiety? Answer to all these can help us find answer to your query. ...Read more

35

35
Globulin Test Tot Protein 8.4, albumin 3.5, Alpha 1 0.3, Alpha 2 0.6, Beta 1.6, Gamma 2.3, m spike not observed, Tot Glob 4.9, A/G 0.7. Any concerns?

Globulin Test Tot Protein 8.4, albumin 3.5, Alpha 1 0.3, Alpha 2 0.6, Beta 1.6, Gamma 2.3, m spike not observed, Tot Glob 4.9, A/G 0.7. Any concerns?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, elevated gamma globulins suggest chronic inflammation and it needs to be investigated. You may consult this site and discuss the matter with your doctor.
https://www. Nlm. Nih. Gov/medlineplus/ency/article/003544.htm ...Read more

36

36
Blood tests shows high gamma globulin & high igg. Ifx shows no monoclonal protein & free light chains are within normal range. What does this mean?

Blood tests shows high gamma globulin & high igg. Ifx shows no monoclonal protein & free light chains are within normal range. What does this mean?

It might be a benign: Many benign processed can cause hypergammaglobulinemia, which are benign elevations without a para -protein or m-spike on serum protein electrophoresis (spe)> it all depends on how high is the gammaglobulin level and making sure the liver functions are ok and there is no chronic inflammation (like rheumatoid arthritis, sarcoidosis etc) going on inside the body. ...Read more

37

37
A cmp blood test says albumin/globulin ratio is 2.6 (says normal range is 1-2.1). What is this ratio, and what do results mean? Should I be concerned?

A cmp blood test says albumin/globulin ratio is 2.6 (says normal range is 1-2.1). What is this ratio, and what do results mean? Should I be concerned?

I wouldn't worry: High albumin doesn't occur except in dehydration which also raises globulin, so your total globulin is a bit low overall. Chances are you're one of the folks who makes less in the way of antibodies than other folks, at least right now. This level's no danger to you. These investigations are seldom productive and if you feel well, I'd simply be thankful for good health and keep an eye on it. ...Read more

38

38
Labs show serum albumin 3.9 (ref. Range 3.5-5.5)and globulin at 1.9 range (1.5-4.5) but says total serum protein low at 5.8 range (6.0-8.5) what gives?

Probably nothing.: Total protein consists of the sum of the globulin proteins and albumin. Since the individual values for globulin and Albumin are normal, it is questionable that there is anything wrong. This may just be normal for you. ...Read more

39

39
Hepc, cirohsis, last 2 reports, alt/ast/bilirubin/globulin etc abnormal, new rep. All within range. Except globulin n albumin do we consider improvement?

Hepc, cirohsis, last 2 reports, alt/ast/bilirubin/globulin etc abnormal, new rep. All within range. Except globulin n albumin do we consider improvement?

Yes: With improvement or normalization of the liver function tests, one can assume the level of infection of the liver is lower - better. Continue an optimal diet that will provide better resistance.
Sources for that: www. Drmcdougall. Com; "food for life"; "eat right, live longer"; and "eat to live". ...Read more

40

40
Albumin 2.79g/dl, globulin 4.38 g/dl, a/g ratio is 0.64 g/dl. Rest of the liver function bllod test within range. Have hep c n cirohsis. Advice?

Albumin 2.79g/dl, globulin 4.38 g/dl, a/g ratio is 0.64 g/dl. Rest of the liver function bllod test within range. Have hep c n cirohsis. Advice?

Hepatologist: Your test results show lack of acute inflammation in the liver, but the presence of hepatitis c that has already caused cirrhosis and decreased liver function means your management and possible treatments should be managed by an expert - a hepatologist or infectious disease specialist. ...Read more