Top
10
Doctor insights on: Beta 2 Microglobulin Serum

Share
1

1
What does a test result for beta 2 microglobulin of 2.47 mean?

What does a test result for beta 2 microglobulin of 2.47 mean?

B2M: It means that b2m is high. The normal range is <0.2. It is not a diagnostic test. It is done to follow the disease and prognosis for mm, leukemia, cancer, and kidney function. It is done with other diagnostic modalities. Good luck. ...Read more

Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more


2

2
What does a high beta-2 microglobulin indicate?

What does a high beta-2 microglobulin indicate?

Disease activity: Beta 2 microglobulin is not diagnostic of a given disease but is usually an indicator of disease severity, e.g., multiple myeloma, lymphoma and some inflammatory conditions. See this site for more info. http://emedicine.medscape.com/article/2086864-overview#aw2aab6b2 ...Read more

3

3
What are normal beta 2 microglobulin levels in a healthy individual?

What are normal beta 2 microglobulin levels in a healthy individual?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, You may consult this site for information on this topic. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9234 ...Read more

5

5
My recent blood test INR 1.12 APTT ratio 1.16 Beta-2 Microglobulin 1.50mg/L are they ok?

My recent blood test
INR 1.12
APTT ratio 1.16
Beta-2 Microglobulin 1.50mg/L
are they ok?

It depends: Yes these values are all within normal limits, but depending upon the issues of what these tests were performed for that could either be a good thing or a bad thing or possibly indifferent. ...Read more

See 4 more doctor answers
7

7
Beta 2 microglobulin is 1.5 ,is it normal?have not been diagnosed with any myeloid malignancy(not been tested) but Immature grans is 0.6, normal CBC

Beta 2 microglobulin is 1.5 ,is it  normal?have not been diagnosed with any myeloid malignancy(not been tested) but Immature grans is 0.6, normal CBC

I must caution you: ...that, without knowing the units associated with these values, I can't be certain that yours are normal. That said, a granulocyte count of less than 2% and beta 2 microglobulin of less than 16 mcg/dl are both normal values. However, as always, history, physical exam & other lab tests must be taken into consideration when interpreting test results. Best wishes. Dr. Anne ...Read more

8

8
Can there be different opinion on beta 2 microglobulin and bone marrow biopsy regarding detection on multiple myeloma?

Can there be different opinion on beta 2 
microglobulin and bone marrow biopsy regarding detection on multiple myeloma?

Beta 2 Microglobulin: Is a way of following myeloma response to therapy. The problem is that it can be elevated in other conditions- including benign ones. I've seen it very high in patients with kidney dysfunction. So the leel could be different than the bone marrow, which is the only real way to prove multiple myeloma. ...Read more

See 1 more doctor answer
9

9
Specimen of clotted blood Results-- B2 Microglobulin=3.10 mg/l (Normal - 0.81 to 2.19 mg/l)?

Specimen of clotted blood
Results-- B2 Microglobulin=3.10 mg/l (Normal - 0.81 to 2.19 mg/l)?

B2 microglobulin: ..can be elevated in many diseases, but is usually used to estimate prognosis & monitor progress in patients with multiple myeloma. A level less than 4 MICROGRAMS (not milligrams) is associated with a good prognosis. However, without having any clinical information about you, I can't say much more than that. ...Read more

10

10
My beta2 microglobulin is 2.47. What does that mean?

My beta2 microglobulin is 2.47.  What does that mean?

Lab data: Without clinical correlation it may mean nothing. Beta 2 microglobulin in patients on hemodialysis can aggregate into amyloid fibers in joint spaces, (dialysis-related amyloidosis). It is also elevated in patients with multiple myeloma or lymphoma but is not diagnostic of these disease. It may account for secondary amyloidosis. As an isolated finding there is no telling what it means. ...Read more

11

11
After 6 cycles of rchop 21 and 30gy of igrt for stage 1 grade 3 nhl, beta2-microglobulin is 2600 ng/ml. Is this high level a cause of concern?

After 6 cycles of rchop 21 and 30gy of igrt for stage 1 grade 3 nhl, beta2-microglobulin is 2600 ng/ml. Is this high level a cause of concern?

B2M is a nonspecific: Marker of cell turnover. The value would be hard to interpret if ordered during or shortly after cancer therapy. It has prognostic importance as a baseline (prior to treatment). ...Read more

12

12
Axilary & supraclavicular lymph nodes swollen both underarm, neck node not swollen beta2-microglobulin 2.21h, poss sarc dx, no infection, cancer issue?

Might need biopsy: You have significant lymphadenopathy which could be the result of an infection or could be related to a malignancy. Most primary care docs will treat with antibiotics and then refer for a biopsy if no improvement within a couple weeks. If a biopsy is needed it can often be done by an interventional radiologist (needle biopsy) and then sent to a pathologist for evaluation. ...Read more

13

13
Serum free light chains increased ratio normal. lambda immunofixation with 4% m spike in beta 2 region in urine only. recommended next step 4 anemia?

Serum free light chains increased ratio normal. lambda immunofixation with 4% m spike in beta 2 region in urine only.  recommended next step 4 anemia?

Spike in UPEP: If you have an abnormal M spike on your urine protein electrophoresis (UPEP), that suggests there is some abnormal cells making excess gamma globulin ( a monoclonal gammopathy). A next step would normally include a bone marrow aspirate and biopsy - this reveals what the abnormality of the blood forming cells causing this is. ...Read more

14

14
Hcg beta serum is below 1.2 what does it mean?

Hcg beta serum is below 1.2 what does it mean?

Not pregnant: Nearly all labs measuring HCG will have a cut off of 2 or 5 (depending on the lab) as representing a negative. Thus 1.2 is negative by nearly all standards. If one is worried, you can always repeat the test, but most labs report HCG as < 2 or < 5. Hope that helps. ...Read more

16

16
What is the best time to take a Quantitative Serum Beta HCG test?

What is the best time to take a Quantitative Serum Beta HCG test?

3 wks after sex: There is no need to rush. A pregnancy test gives a reliable result 3 weeks after sex (3 wks after when conception might have occurred), or 1 week after missing a period. If done sooner, a positive result is likely real, but a negative result may be due to testing too soon, and thus lead to a repeat test. If a woman gets her normal regular period, then she is not pregnant, and a test isn't needed. ...Read more

17

17
Under which circumstances will a "normal" E.Coli gain on its activity? Is a positive serum beta glucuronidase test related to such activity? TY.

Under which circumstances will a "normal" E.Coli gain on its activity? Is a positive serum beta glucuronidase test related to such activity? TY.

Hard to say/depends: This likely depends on what is considered "normal" about the E. coli and it's activity. E. coli is part of the normal "gut" flora. It's when certain other forms of E. coli like the O157:H7 strain get in the digestive tract that issues occur. So it's hard to say how activity would be affected unless abnormal E. coli get in there. The Bgluc test is homologous to the E. coli Bgalact enzyme. ...Read more

18

18
Severe insomnia since last two to three months.. I got my blood tests done and my serum ferritin came out to be v low around 5..Are they related?

Insomnia : Low ferritin levels indicate that you are at a higher risk of having iron deficiency anemia. Although there is no link between iron deficiency and insomnia there is a relationship between restless leg syndrome and low iron levels. In restless leg syndrome patients feel a need to move their legs when in bed keeping them from sleeping. Check with your doctor to see if replacing iron is necessary. ...Read more

See 1 more doctor answer
19

19
I have Hepatitus A from last two weeks. Today the level of Serum Bilirubin is 7.5 mg/dl, Alkaline phophatase 366U/L, SGPT(ALT) 178U/L. Suggest me plz?

I have Hepatitus A from last two weeks.  Today the level of Serum Bilirubin is 7.5 mg/dl, Alkaline phophatase 366U/L, SGPT(ALT) 178U/L. Suggest me plz?

Depends on trend: Relevance of these numbers depends on the trend. If they are decreasing, that is good. It can take several weeks in many cases for the ALT to return to normal. ...Read more

See 1 more doctor answer