Top
10
Doctor insights on: Beta 2 Glycoprotein 1 Ab Ig A, Ig M, And Ig G

Share
1

1
Beta-2 glycoprotein i ab, IgM 48 high. What does this mean?

Beta-2 glycoprotein i ab, IgM 48 high. What does this mean?

Blood Clots too much: Beta-2 glycoprotein 1 antibody tests are used to help find the cause of unexplained blood clots (thrombotic episodes) or recurrent miscarriages. Also used to diagnose antiphospholipid syndrome (APS), or to detect the autoantibodies in someone with another autoimmune disorder. Sometimes may be ordered with cardiolipin antibody and lupus anticoagulant testing. IgG, IgM or IgA may be elevated. ...Read more

2

2
Is aps possible if beta-2 glycoprotein , lupus anticoagulant and cardiolipin-ig-(g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?

Is aps possible if beta-2 glycoprotein , lupus anticoagulant and cardiolipin-ig-(g/m/a)are >0.2. Is test to be repeated in 1-2yrs if once negative?

No: It is highly unlikely that you have apa syndrome if the tests are negative. The test values can vary from time to time and may even be negative on rare occasions. However, if you have symptoms and the tests are negative at that time then you need to find another cause. ...Read more

3

3
Do you rule out aps if anticardiolipin antibody and beta 2 glycoprotein (both IgG and igm) are often elevated but in borderline and weakly positive range?

Do you rule out aps if anticardiolipin antibody and beta 2 glycoprotein (both IgG and igm) are often elevated but in borderline and weakly positive range?

See below: There are certain criteria that must be met in order for one to have aps. One of which is that one must have some type of thrombotic event. Antibodies alone do not make the diagnosis. Without knowing full details regarding your case, it is difficult to say whether you do or not. ...Read more

See 2 more doctor answers
5

5
Does anticardiolipin IgM (115ug/l) x 3 have any significance when it is rasied on its own? LA Positive but beta glycoprotein & other antibodies neg

Does anticardiolipin IgM (115ug/l) x 3 have any significance when it is rasied on its own?  LA Positive but beta glycoprotein & other antibodies neg

Higher future risk: The cause of an elevated aCL without other diseases is unknown. That said, 50% of people with + lupus anticoagulant have or will have SLE. Presumably, manifestations require the aCL plus another problem - infection, one of a number of drugs, pregnancy, BC pills, etc. The significance is the higher than normal risk in the face of future immunological injury ...Read more

6

6
What is the definition or description of: antibodies to b2 glycoprotein i present?

What is the definition or description of: antibodies to b2 glycoprotein i present?

Lupus erythomatosis.: Antibodies to beta 2- glycoprotein 1 is found in lupus disease, and in a condition called primary antiphospholipid antibody syndrome. This could be of igm or igg class. The relevance of the presence of these antibodies in these conditions in clinical practice is not very clear. The antibody can promote thrombosis. ...Read more

See 1 more doctor answer
7

7
Can you take spironolactone + Lipitor (atorvastatin) ? spironolactone will increase the level or effect of Lipitor (atorvastatin) by P-glycoprotein (MDR1) efflux transporter. ?

Can you take spironolactone + Lipitor (atorvastatin) ?
spironolactone will increase the level or effect of Lipitor (atorvastatin) by P-glycoprotein (MDR1) efflux transporter. ?

Take together: Two common drug information references fail to support this information. One describes a small, more theoretical interaction that may result in an increase in spironolactone activity (but not atorvastatin), but these two medications are commonly used together without adverse effect. ...Read more

See 1 more doctor answer
8

8
How often are glycoprotein inhibitors used prior to surgery for patients needing to be off plavix (clopidogrel) prior to surgery? Is it a good option? I had 2 de stents oct 2012. Need to remove tumor in abdomen.

How often are glycoprotein inhibitors used prior to surgery for patients needing to be off plavix (clopidogrel) prior to surgery? Is it a good option? I had 2 de stents oct 2012. Need to remove tumor in abdomen.

GPIIb/IIIa use: Gpiib/iiia inhibitors are indicated for unstable angina, heart attack and stent placement and not for all different kind of surgery. Having abdomen tumor make you high risk of bleeding. Need physician supervision to monitor platelets, pt, inr, act, aptt if it is used. You already have de stents. May want to discuss about Lovenox (enoxaparin) with short half life. Your doctor has to observe you closely. Good luck. ...Read more

See 1 more doctor answer
9

9
Please tell me, could a person with a myelin associated glycoprotein antibody, IgM have multiple sclerosis?

Please tell me, could a person with a myelin associated glycoprotein antibody, IgM have multiple sclerosis?

Possible comorbidity: The mag levels do not help confirm multiple sclerosis or even seem to correlate with this disorder, and typically, point toward problems with the peripheral nervous system. You could have ms and another condition, and a neurologist might help with both. Suggest you discuss your test and seek correlations if any. ...Read more