Doctor insights on:
Best Subacute Cutaneous Lupus Treatment
No sun, some Rx: Sun protection, topical steroids. If no better in 2-4 weeks, cortisone injections into the lesions or topical calcineurin inhibitors. If still no better in 2-4 more weeks, oral hydroxychloroquine, an anti-malarial medication. There are even further treatment for refractory cases but the above usually works. ...Read more
Skin is the largest and one of most complex organs of body. 3 layers: epidermis (outer), dermis (main part) and subcutaneous layers covers entire body, contains many specialized cells, maintains body temp, gathers sensory info from the outer world, has extremely important immune functions. It can give crucial clues as to what is internal. Dermatology and plastic surgery are ...Read more
Tests for cutan lupu: Extractable nuclear antigen known as ena, also known as antiro/la antibodies are aalways positive in patients with subacute cutaneous lupus and skin biopsy may be diagnostic.Direct immunoflorescence test may show positive antibody deposition along the basement membrane. ...Read more
Rash: There are different types of subacute cutaneous lupus (scle) - a characteristic form has lesions that may have an annular configuration, with raised red borders and central clearing. A second type of scle has psoriasis-like lesions with red scaly patches on the arms, shoulders, neck, and trunk and fewer patches on the face. This rash is characteristically made worse by sunshine - photosensitive. ...Read more
Subacute cutaneous lupus: This is an autoimmune disease which is exacerbated by sun exposure. It includes a rash on sun exposed areas such as the face, chest, and arms. It may be seen in Inc. his and in adults. It is often associated with abnormal immunology studies such as an SSA and SSB autoantibodies. The treatment differs versus on the severity of the skin lesions and includes both topical and oral medications. ...Read more
Biopsy, blood test: Rashes are not always easy to diagnose. Simple acne or severe plaque psoriasis may not require further tests to diagnose the condition. In scle, the rash may require a biopsy which is the very best test. Blood tests may reveal a positive antinuclear antibody (ANA) and a positive ssa antibody. ...Read more
How do the rashes associated with annular lichen planus and subacute cutaneous lupus differ in appearance?
Are there any OTC treatments to reduce the scarring to the face from cutaneous lupus? Insurance won't cover dermatologist. Taking plaquenil (hydroxychloroquine) to treat.
Many!: Many options, depending on severity and your current treatment. Pulsing IV steroids at high dose, cellcept, (mycophenolate mofetil) benlysta, azothioprine, cyclophosphamide, azothioprine, Methotrexate are all options, alone or in combination. Your treatment should be coordinated by someone in rheumatology and/or nephrology! ...Read more
Skin sarcoidosis!: Lupus perneo is a manifestation of sarcoidosis, usually seen in chronic disease. Intra-lesional steroid injections can help, as can systemic therapy. Sarcoidosis is an autoimmune disease that can affect many organs, but more common and serious, the lungs. This disease needs rheumatologic management. The new tnf-alpha inhibotrs seem to work quite well, although this is off-label use! ...Read more
What is lichenoid lupus erythematosus? How is it different from discoid lupus erythematosus? Best course of treatment that does not involve oral meds?
Oral agents best: Lichenoid lupus refers to a specific type if rash sometimes photosensitive, which is oftern red and raised. It occurs between the dermis and epidermis under the microscope. Discoid may also start as a red area but will cause atrophy and scarring. The best treatment is usually the oral agent plaquenil (hydroxychloroquine). Other options include sunscreen, moisturizers and topical steroids if the areas are small. ...Read more
Probably yes: There is no reason why Lisinopril cannot be used to treat high blood pressure in patients diagnosed with lupus nephritis. In fact, it may be the drug of choice in lupus patients who are also spilling protein in their urine. It may be need to be used with some caution in those patients with more advanced cases of lupus-related kidney disease as it may contribute to high levels of potassium. ...Read more
S L E : Systemic lupus erythematosus is an auto immune disease, that can affect skin, joints, kodneys, brain, and other organs.Auto immune means bodys immune system mistakenly attacks healthy tissues it is treated with steroids and non steroidal anti inflammatory meds, avoid sun and wear protective clothing. Cytotoxic drugs if you do not respond to cortico steroids cytotoxics have side effects need to be monit. ...Read moreSee 1 more doctor answer
Not usually: It will most often resolve on its own. ...Read more
Autoantibodies: Lupus nephritis is produced when autoantibodies cause inflammation of the kidney glomeruli and tubules. It is one of the organs affected by lupus Often a biopsy needed to determine severity and prognosis-class I,II,III, IV, V, and VI, with six being the most severe. Treatment includes corticosteroid, azothioprin, cyclophosamide, mycophenelate mofetil,cyclosporin. dialysis. Remission can occur. ...Read more
Why don't men want to go to doctors? My husband has discoid lupus, and I feel I have to drag him in to be seen. What will happen to him without treatment?
This is an autoimmune disease which is exacerbated by sun exposure. It includes a rash on sun exposed areas such as the face, chest, and arms. It may be seen in Inc. his and in adults. It is often associated with abnormal immunology studies such as an SSA and SSB autoantibodies. The treatment differs versus on the severity of the skin lesions and includes both ...Read more
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