Doctor insights on:
Best Jejunal Cancer Program
Best institution for experimental protocol to add to nexavar (sorafenib) for metastatic HCC - 34 yo Asian male, s/p omental resection?
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Surgery, chemo: Depending on the stage, an operation is usually necessary to remove the diseased portion of the colon along with its nearby lymph nodes. Then, depending on if the cancer has spread to those lymph nodes impacts whether you will also need chemotherapy. If the cancer has already spread beyond the colon, sometimes you start with chemo. ...Read moreSee 2 more doctor answers
Kras braf tests are: Molecular testing of colon mets tissue for gene mutations of those two loci predict patients who will or will not respond to precision anti tumor (epidermal growth factor receptor protein) antibodies. These were FDA okd and clinically proven in hundreds of tested and treated patients to be beneficial in survival. Oncologists versed with and pathologists who process these tumor tissues shld help U. ...Read more
Lifestyle choices: Cigarette smoking, promiscuous unprotected sex, and low fiber diet or positve family history are simple answers for your listed afflictions, respectively. Screening tests for lung cancer (CT chest), and colon cancer (colonoscopy) are available. Check the American Cancer Society website to determine if you fit the appropriate category to have these exams. ...Read more
Experts, might someone recommend nexavar (sorafenib) for a stage 4 inactive neuroendocrine pancreatic cancer patient?
Possibly: Stage 4 indicates that you have net at a site distant from the pancreas or regional lymph node, likely the liver. Not clear what you mean by"inactive", whether you mean it is stable or not secreting any substance. In any case, sorafenib (nexavar) is being tested in metastatic net in clinical trials (http://clinicaltrials.Gov/ct2/show/nct00131911) & (http://www.Ncbi.Nlm.Nih.Gov/pubmed/23475104). ...Read moreSee 1 more doctor answer
Chemo: Stage 4 colon Ca best handled by assuring that the primary is removed so other sites of spread don't appear. Systemic chemo then used for primary control but if lesions are in one area such as liver or lung, those sites approached if lesions small and resectable. If liver lesions get numerous then chemo embolization or Yt microspheres used. Thorascopic resection employed with some lung lesions. ...Read more
Well: Well, Across the board, Stage IV colon cancer is not a good thing to have. Statistically, the main survival with chemotherapy is about 2-3 years unfortunately. I have patients that are alive and relatively well on palliative chemotherapy after many more years. Every case is different and many options exists depending upon where the metastasis is located at. Usually Chemotherapy is the main treatme ...Read more
Possibly: Removal of liver metastases can sometimes be helpful for patients with colon cancer. A remarkable amount of cancer can be removed usually after there has been some response to chemotherapy. If surgery is not recommended alternatives such as radioembolization, chemoembolization, radiosurgery, or rfa or cryoablation may be considered. Get with an experienced team to determine the best course! ...Read moreSee 5 more doctor answers
So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more
jejunum is the largest segment of small intestine situated between duodenum and ileum. While malignancies of bowel are most commonly found in the colon, the most frequent tumors of SB were GIST (36%) followed by lymphomas (24%) and adenocarcinomas (18%). Metastasis to lumen of small bowel also found in rare situations arising from primaries of ...Read more
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