Doctor insights on:
Best Chronic Myelogenous Leukemia Treatment
High deductible. Limited coverage of outpatient care. Would really help to know what tests, evaluations are required to diagnose chronic myelogenous leukemia and follow it after treatment.?
Nccn.org: Awful predicament. CML is one of the success stories with the new therapies, but proper follow up is important to assure optimal long term survival on the new oral agents. There are good patient assistance programs to assist with your medications. Review the web address above and CML page with your doc to plan the needed tests. ...Read more
Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Multiple: There are medications called tyrosine kinase inhibitors. They block this enzyme and treat the leukemia. There are currently three on the market, imatinib, nilotinib and dasatinib. Other treatments include bone marrow transplant but rarely done now because these medications are available. Hope this helps. ...Read moreSee 1 more doctor answer
I live in a college town with many healers who use Asian treatments. Will they work on chronic myelogenous leukemia?
Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. ...Read more
CML: CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case. ...Read moreSee 1 more doctor answer
Difficult situation: This has happened to many women taking Imatinib (Gleevec) for CML. Most women have had a normal baby, others aborted the baby with help from a Gynecologist. I believe it is safe to carry the baby to term but there is some risk the drugs can harm the bay but it is not proven. So if you want to keep the baby then you should take this risk, but be closely monitored by a CML expert. First 3 months are ...Read more
By oncologist: This is a somewhat indolent form of leukemia which responds to treatment and can be carried for many years without major illenss. You could only have known about this if you had a bone marrow and blood test from your oncologist whose recommendations i would continue to follow. ...Read moreSee 2 more doctor answers
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