Doctor insights on:
What are the possible causes of both ITP & Bernard-Soulier Syndrome in a person? What effect, if any, do they have together? Thanks for your input.
Platelet troubles: Bernard-Soulier features a small number of large platelets, lifelong and without autimmunity being a factor. In ITP, the immune system destroys platelets and those that remain are often quite large. It's possible that you have only one of these, as both feature a diminished number of platelets and increased platelet size. Get a review by a good up-to-date hematologist. ...Read more
Thrombocytopenia: DIC-disseminated intravascular coagulation is thought to destroy platelets as they are trapped or damaged by fibrin strands within the vessels. BSS is associated with an intrinsic glycoprotein defect in the platelets themselves that results in decreased survival and poor function. ...Read more