Doctor insights on:
Berger Disease Drugs
How many people are suffering from IgA nephropathy disease in Canada? (%) Thank you for your time. :)
Hard to tell: There are some incidence reports for several countries, but didn't see a report for Canada. Canada may be in the low end of the range of about 15-40 new cases per million people per year. That would be ~525 new cases per year, for Canada's 35 million people. The prevalence number is the number of total living patients with it, not just the annual new cases (Ministry of Health may know the number). ...Read more
I've had IgA nephropathy, are there methods to self-medicate, and is this disease serious or really incurable?
Fishoil, fishoil: So far no other options to self medicate. It is usually incurable. Some people do better spontaneously or with fishoil. Others do worse and may need dialysis in the future and/or transplant. People tend to ignore f/u since there is no proven treatment. F/u will save you bad surprises also new treatments may develop.Blood pressure is ideal. Aggressive salt restriction under 2000mg/day if high bp. ...Read moreSee 1 more doctor answer
My 9 yr old son has strep throat and a kidney disease called IgA nephropathy it's a kidney disorder started when he was 5. Kidney biopsy ?
Confusing question: Although some strep strains can cause kidney problems, early treatment usually avoids them. If the kid has a pre-existing kidney problem, the need for a biopsy is best determined by the docs who know him best. A recent strep infection would not require such an invasive procedure, but a significant change in kidney function might. ...Read moreSee 1 more doctor answer
Does a six-month regimen of prednisone (for IGA nephropathy) risk damage to hips/joints? Husband is having hip pain after a month on the drug.
Prednisone effect: One of the major side effects of Prednisone is bone loss. The importance of it depends on the underlying bone health/condition of the individual. We generally acquire a bone density scan before starting long term steroid therapy and if we find signs of underlying osteoporosis we treat it at the same time (with Calcium, Vitamin D analogs, and Bisphosphonates). Your husband probably need one now! ...Read more
Blood in the urine: Iga nephropathy usually does not present with any noticable symptoms. However when you see your doctor, the doctor may notice blood in your urine. Also the doctor may notice protein in your urine. In some occassions, you may develop swelling in your feet. ...Read moreSee 1 more doctor answer
Proteinuria IgAN: Good question. Conventional approach is to commence an ACE Inhibitor and then titrate the dose upward slowly while measuring urine protein. Goal is to reduce proteinuria by at least 50%. Your BP program may require modification. Prednisone is also occasionally used for a flare of IgAN. ...Read moreSee 4 more doctor answers
Low-protein & salt: Nephropathy, kidney disease, regardless of cause, generally dictates a diet lower in protein and in sodium (table salt). The degree of restriction depends on the degree of current kidney compromise, the expectation of future damage, & the presence of other contributory risk factors like diabetes or hypertension. ...Read more
Sussceptibility: Iga nephropathy is a one of the most common glomerulonephritis ie a type of kidney disease in the world.The cause is not completely clear.Its a form of immunoglobulin ie a protein normally made in all of us, which gets deposited in the filter of the kidney, ie glomerulus and causes damage as it is slightly altered in those individuals. ...Read moreSee 1 more doctor answer
Low antigen diet: Patients with IgAN have an immune problem. An Italian study by Ferri reported a marked reduction in proteinuria in IgAN patients put on a strict low-antigen diet (a diet free of foods likely to cause immune response- http://www.ncbi.nlm.nih.gov/pubmed/8302454). Such diets are low in wheat, soy, food preservatives, and food coloring. Contact Claudio Ferri Univ L'Aquila Coppito, Italy for more info ...Read more
Supportive care: Igan can cause sig back/flank pain. This may be unrelated to severity of disease (you may have severe pain but normal kidney function); treatment is challenging. Narcotics are addictive and will make you sleepy; nsaids(like ibuprofen) are toxic to kidney; tyelenol is safe but may not help. Try exercise/yoga/acupuncture/gabapentin/tricyclic anti-depressants. ...Read more
What are the chances that my kidneys will fail at some point because of my HSP and IgA nephropathy? Many thanks
My brother's cre level is 15 after d. He is in sta 5 of IgA nephropathy.His blood goup is o-neg what would u suggest in this case.Hard to find a donor?
Not short.: Iga nephropathy sometimes resolves spontaneously. Many cases have stable disease i.e. With no deterioration for long years. Severe cases however, will develop end-stage renal disease and require dialysis. They will be eligible for transplant that can be repeated if needed. Each transplant could give on the average 90%+ of 10-15 years renal graft survival. ...Read more
Kidney disease: In nephrotic syndrome the kidney excretes large amounts of protein. It can be caused by autoimmune diseases, but also by certain heavy metals, outdated medications and genetic diseases. Iga nephropathy is an autoimmune disease, actually glomerulonephritis that can lead to renal failure. It is frequently associated with a vasculitic rash, typically on legs and buttock (henoch-schoenlein purpura). ...Read more