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Doctor insights on: Benicar Hct

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Dr. George Mathew
134 doctors shared insights

Olmesartan (Definition)

Olmesartan is an angiotensin II blocker which is a kind of blood ...Read more


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Dear MD, Pharma: How long it takes for Benicar/HCT to be completely out of your system. How long it continue to control BP after you stop it. ?

Dear MD, Pharma: How long it takes for Benicar/HCT to be completely out of your system. How long it continue to control BP after you stop it.
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Variable: This a two drug combination the half live for Benicar (olmesartan) is 13 hr & hctz half live is variable 5.6-14.7 hr. That means that have the dose is metabolized on that time. Several days until it is completely eliminated ...Read more

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Benicar/hct drug info sheet shows little differences in antihypertensive effect between dosages 40/12.5=16/10 while 20/12.5 =17/8. Would 20/12.5 be ok?

Benicar/hct drug info sheet shows little differences in antihypertensive effect between dosages 40/12.5=16/10 while 20/12.5 =17/8. Would 20/12.5 be ok?

Response: Your BP goal should be <140/90. If you have heart disease, diabetes or kidney disease then it should be <130/80. Please go by response and use the smallest dose required to achieve the goals. Lifestyle modification with achieving ideal body weight, increasing exercise, watching salt intake, dash diet and moderation in alcohol intake will help decrease BP and minimize medication usage. ...Read more

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Taking Benicar/HCT , and concern about FDA ROADMAP trial study that it increased risk of cardiovascular death. How safe is it and how widely used?

Taking Benicar/HCT , and concern about FDA ROADMAP trial study that  it  increased risk of cardiovascular death. How safe is it and how widely used?

Still safe and used: Benicar (olmesartan) w/ and w/out HCT sells at 8.3 million Rxs/year, and it's in the Top 40 most prescribed. (See Medscape art. #829246.) The most recent info from the FDA was in June 2014; it reported it "found no clear evidence of increased cardiovascular risks." The increased deaths in ROADMAP came mostly in those with the lowest BP. It may be too aggressive BP control rather than the drug is the danger. ...Read more

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I am currently taking benicar-hct 40 12.5. Due to change in insurance I can't afford to fill prescriptions. Can I change to Benicar (olmesartan) w/OTc water pill?

I am currently taking benicar-hct 40 12.5.  Due to change in insurance I can't afford to fill prescriptions. Can I change to Benicar (olmesartan) w/OTc water pill?

Follow close w/ doc: This is probably reasonable however I would recommend your be evaluated more frequently with your doctor until you both are sure this change is reasonable, ...Read more

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What is the peak time and half-life of amlodipine, pravachol, (pravastatin) and benicar/hct medicines respectively. Thanks for the help in advance.

What is the peak time and half-life of amlodipine, pravachol, (pravastatin)  and benicar/hct medicines respectively. Thanks for the help in advance.

LookOnline & Empower: Search engines, esp google, can rapidly find these answers for you (& me), e.g. Search "amlodipine t½" & go to nih, fda or edu websites. Keep in mind that chemical t½ life & physiologic t½ life may be very different, data is only a small group average & there are many variables. Also keep in mind that your primary medical decision maker (primary physician, if you will) is always you, no one else. ...Read more

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Medlineplus site has warning: spironolactone has caused tumors in laboratory animals. How safe is it. Also can you use with bb bystolic (nebivolol) &benicar/hct?

Medlineplus site has warning: spironolactone has caused tumors in laboratory animals. How safe is it. Also can you use with bb bystolic (nebivolol) &benicar/hct?

Very safe: Spironolactone has been in use for decades, so i would not worry about the animal data. The drug is safe in people and that is all that matters. You can use it in any fashion as per your doctor recommendations. ...Read more

Dr. George Mathew
129 doctors shared insights

Benicar (Definition)

Benicar is an angiotensin II blocker which is a kind of blood ...Read more