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Doctor insights on: Bence Jones Protein In Urine

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Is bence jones protein different from regular protein in urine?

Is bence jones protein different from regular protein in urine?

Yes: Usually, Albumin or a mix of proteins are the stuff in "proteinuria". Bence-jones is immunoglobulin light chains and is much more worrisome. It also often doesn't show on the urine dipsticks that are the usual screen for proteinuria. ...Read more

Urine (Definition)

Urine is the product of the kidneys, which is produced to eliminate the waste products of metabolism, manage body fluid balance, &maintain acid-base balance. The blood is first filtered by the kidneys, and the composition of the resulting fluid is then altered depending on the body's needs. It is composed of mostly water, and breakdown products from blood cells impart ...Read more


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KL FLC chains to rule out light chain myeloma? No m spike in serum or 24-hr urine, but lambda bence jones in spot urine but md didnt order urine ifa?

KL FLC chains to rule out light chain myeloma? No m spike in serum or 24-hr urine, but lambda bence jones in spot urine but md didnt order urine ifa?

Does not add up: How do you know it was lambda bence jones in urine without a urine IFA? This issue is not suitable for this forum as a diagnosis of myeloma requires results of other tests as well, e.g., bone X-ray, bone marrow examination, serum calcium and beta 2 microglobulin levels etc. It would be prudent to discuss the matter with a hematologist. ...Read more

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Protine in urine?

Protine in urine?

Discuss with MD: You need to discuss further workup with your physician. Protein in urine can be caused by several things but the main causes are hypertension and diabetes. ...Read more

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Blood protein and leukocytes in urine?

Blood protein and leukocytes in urine?

Possible infection: Leukocytes can mean infection; protein in the urine is not normal - see your internist for a urinalysis, culture and full evaluation. ...Read more

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Urine results showed 100 mg/dL Protein in urine, Moderate Blood, Total Protein/Creatinine Ratio, Urine 319.7, Red Blood Cells, Urine 4-10, SEC many.

Urine results showed 100 mg/dL Protein in urine, Moderate Blood, Total Protein/Creatinine Ratio, Urine 319.7, Red Blood Cells, Urine 4-10, SEC many.

Sounds like you: had a urine test for infection? Results look like you may have a mild UTI, though some of the numbers do not match up with the test acronym. Make sure you drink plenty of water and take antibiotics given with food. If you have pain on urination, the healthcare provider can give you some medicine to numb that area up for a couple of days. ...Read more

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Kappa light chain in upep. Elevated k/l chains in serum but ratio normal. Wbc, rbc in urine with 2g/d protein. More/which workup/specialist needed?

Kappa light chain in upep. Elevated k/l chains in serum but ratio normal. Wbc, rbc in urine with 2g/d protein. More/which workup/specialist needed?

Nephrologist: You need a nephrologist to follow up on those tests, but your doctor or the doctor who ordered those tests can direct you better, wish you wellness ...Read more

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Rule out light chain myeloma without biopsy or amyloidsis with fat biopsy? Spot urine lambda bence jones, no m spike in serum or urine. Next 24hr ufe?

Rule out light chain myeloma without biopsy or amyloidsis with fat biopsy? Spot urine lambda bence jones, no m spike in serum or urine. Next 24hr ufe?

Urine light chains: hello~ thats an impossible question for me to answer here. My brain will overheat if I have to do that in 421 words. Be kind to us. Please go and see an Oncologist or a smart general internist and he will answer or even manage your case. Remember that not all light chains in the urine means myeloma. See an expert and have him explain the difference between MGUS and myeloma.thanks ...Read more

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Protein and lecocytes in urine test. Why? Alcohol related?

Protein and lecocytes in urine test. Why? Alcohol related?

Not alcohol: Protein can be seen in first void in morning, concentrated urine, or with kidney injury. Leukocytes are a marker of infection. Both should be rechecked when well-hydrated by your dr. Good luck! ...Read more

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Range of creatinine excretion in random urine sample in CKD patient?

Difficult to answer.: Cr varies depending on a host of factors and how you might be measuring and the degree of ckd. Typical production of cr is about 16mg/kg/day in females and about 20% more in males due to larger muscle mass. If the kidneys are at steady state excretion equal s production. ...Read more

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Read that Bence Jones Protein can sometimes appear in 24 hr urine and be missed/normal in serum Free Light Chain Assay? Normal SPEP but no UPEP done..

Read that Bence Jones Protein can sometimes appear in 24 hr urine and be missed/normal in serum Free Light Chain Assay? Normal SPEP but no UPEP done..

No consensus: The serum free light chain assay is newer and is supposed to detect free light chains in serum even before they are detectable in urine. The old protocol was with plasma electrophoresis and urine protein immunofixation. It all depends now on the hematologist's confidence level in the new test. ...Read more

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High BUN level with Trace Protein in Urinalysis . indication of what ?

High BUN level with Trace Protein in Urinalysis .  indication of what ?

Kidney issues: You will need a renal ultrasound, workup, possible CT scan and a 24 hr urine evaluation to rule out intrinsic kidney disease. ...Read more

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How elevated is 30mg/dl of protein in a urine test?

How elevated is 30mg/dl of protein in a urine test?

ANY LEVEL OF: Protein in the urine raises concerns. The more the worse of course. See your doctor please. ...Read more

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Random sample: urine protein 31mg/l urine albumin 5.00mg/l urine creatinine 3.894mmol/l urine albumin creatinine:ratio 1.3mg/mmol is this normal?

Random sample: urine protein 31mg/l urine albumin 5.00mg/l urine creatinine 3.894mmol/l urine albumin creatinine:ratio 1.3mg/mmol is this normal?

Is this a test?: Slight variation in the reports from different laboratories does exist. So, please refer to the attached normal range for interpretation. I'm sure there is such information for you to reconcile. If any doubt, talk and confirm with the attending doctor. Best ... ...Read more

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Could 175g of protein elevate bun in blood 29 and elevated bun in urine 32?

Could 175g of protein elevate bun in blood 29 and elevated bun in urine 32?

YES: Excessive protein intake results in elevated BUN levels in blood and urine. If you are concerned about your kidney function than limit protein intake for a week and recheck Renal Panel. Thanks ...Read more

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My urine has large urine amorphous sediment, small urine calcium oxalate crystals, small bacteria, small mucus , trace protein and sp grav 1.030?

My urine has large urine amorphous sediment, small urine calcium oxalate crystals, small bacteria, small mucus , trace protein and sp grav 1.030?

Sounds normal: All these are common and normal. Your urine is quite concentrated, probably due to limited fluid intake before it was collected; this probably explains the trace protein, which is the only thing mentioned that might be considered slightly abnormal. Discuss with your doctor, but I see no cause for worry. ...Read more

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Consulting for protein trace in urine. ?

Consulting for protein trace in urine. ?

What level?: It depends on much protein is in your urine - it is normal to have transient or small amounts. High amount of proteinuria can manifest as froth or "bubbles" in the urine. Also a 24 hr collection of >3.5 g per 24 hours needs an evaluation. ...Read more

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Slight foamy urine.spot urine test-protein 5mg/dl,creatinine 37mg/dl,albumin 2 mg/litre.Is it normal or proteinuria ?

Proteinuria: We generally calculate the urine protein to creatinine ratio and as long as the ratio is below 300 mg/g it is considered not significant (yours is only 135mg/g) so your proteinuria is not significant. But the Albumin level you mentioned, is it serum (blood) Albumin level? If yes, it is very low and unlikely! Please verify your Albumin level and it's source (blood or urine) . ...Read more

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Dr. Lawrence Kessler
98 doctors shared insights

Protein In Urine (Definition)

Protein is an expensive commodity for the body. The kidneys are entrusted to return protein back to the body during filtering, and not lose it to the urine. Losses > 150mg/day are indicative of a problem with the filtration mechanism of the kidney. A nephrologist should be consulted ...Read more


Protein (Definition)

Proteins are large molecules made up of a smaller class of molecules called amino acids. Proteins play an enormous role in the function of our bodies including enzymes, messengers, replicating dna, ...Read more